Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Stefanie, Dedeurwaerdere"'
Autor:
Liesbeth François, Alessia Romagnolo, Mark J. Luinenburg, Jasper J. Anink, Patrice Godard, Marek Rajman, Jonathan van Eyll, Angelika Mühlebner, Andrew Skelton, James D. Mills, Stefanie Dedeurwaerdere, Eleonora Aronica
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Epilepsy is a chronic and heterogenous disease characterized by recurrent unprovoked seizures, that are commonly resistant to antiseizure medications. This study applies a transcriptome network-based approach across epilepsies aiming to impr
Externí odkaz:
https://doaj.org/article/d55463fe03e3422294e40f44397850cb
Autor:
Isabeau Vermeulen, Natalia Rodriguez-Alvarez, Liesbeth François, Delphine Viot, Fariba Poosti, Eleonora Aronica, Stefanie Dedeurwaerdere, Patrick Barton, Berta Cillero-Pastor, Ron M.A. Heeren
Publikováno v:
Neurobiology of Disease, Vol 195, Iss , Pp 106491- (2024)
Focal cortical dysplasia (FCD) represents a group of diverse localized cortical lesions that are highly epileptogenic and occur due to abnormal brain development caused by genetic mutations, involving the mammalian target of rapamycin (mTOR). These s
Externí odkaz:
https://doaj.org/article/2723c89fd56e4ee1ab8e609121eff546
Autor:
Isabelle Niespodziany, Aurore Frey, Rodrigo Aguirre, Grégory Szczesny, Stefanie Dedeurwaerdere
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S617- (2023)
Externí odkaz:
https://doaj.org/article/7981d864e168467faf84dee70b76196f
Autor:
Peravina Thergarajan, Matthew R. Hudson, Irena Carmichael, Jérôme Clasadonte, Stefanie Dedeurwaerdere, Terence J. O'Brien, Nigel C. Jones, Idrish Ali
Publikováno v:
Neurobiology of Disease, Vol 168, Iss , Pp 105688- (2022)
Objective: Status epilepticus (SE) models in rodents are commonly used to research mesial temporal lobe epilepsy (mTLE) in translational epilepsy research. However, due to differences in susceptibility of mice strains to chemoconvulsants, developing
Externí odkaz:
https://doaj.org/article/abcb5420f3094f8bbe958023e5e92057
Autor:
Daniele Bertoglio, Elisabeth Jonckers, Idrish Ali, Marleen Verhoye, Annemie Van der Linden, Stefanie Dedeurwaerdere
Publikováno v:
Neurobiology of Disease, Vol 127, Iss , Pp 45-52 (2019)
Different types of brain injury, such as status epilepticus (SE), trauma, or stroke may initiate the process of epileptogenesis and lead to the development of temporal lobe epilepsy. Epileptogenesis is characterized by an initial latent period during
Externí odkaz:
https://doaj.org/article/76469d7f52564d65a1958d5e7c64cc16
Autor:
Daniele Bertoglio, Halima Amhaoul, Joery Goossens, Idrish Ali, Elisabeth Jonckers, Tom Bijnens, Matteo Siano, Leonie wyffels, Jeroen Verhaeghe, Annemie Van der Linden, Steven Staelens, Stefanie Dedeurwaerdere
Publikováno v:
NeuroImage: Clinical, Vol 31, Iss , Pp 102701- (2021)
Neuroinflammation is a key component of epileptogenesis, the process leading to acquired epilepsy. In recent years, with the development of non-invasive in vivo positron emission tomography (PET) imaging of translocator protein 18 kDa (TSPO), a marke
Externí odkaz:
https://doaj.org/article/a00c894885164fe5bc81f163bc88c743
Autor:
Sebastiaan Van De Vijver, Stephan Missault, Jeroen Van Soom, Pieter Van Der Veken, Koen Augustyns, Jurgen Joossens, Stefanie Dedeurwaerdere, Michele Giugliano
Publikováno v:
PeerJ, Vol 7, p e6796 (2019)
Neurons are embedded in an extracellular matrix (ECM), which functions both as a scaffold and as a regulator of neuronal function. The ECM is in turn dynamically altered through the action of serine proteases, which break down its constituents. This
Externí odkaz:
https://doaj.org/article/7fadd74250a346db96f04537f7b04515
Autor:
Ute Häussler, João Neres, Catherine Vandenplas, Caroline Eykens, Irena Kadiu, Carolin Schramm, Renaud Fleurance, Phil Stanley, Patrice Godard, Laurane de Mot, Jonathan van Eyll, Klaus-Peter Knobeloch, Carola A. Haas, Stefanie Dedeurwaerdere
Structural epilepsies display complex immune activation signatures; however, it is unclear which neuroinflammatory pathways drive disease pathobiology. Transcriptome studies of brain resections from mesial temporal lobe epilepsy (mTLE) patients revea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4335cefb20212e8fc9401815cd3fa9c1
https://doi.org/10.21203/rs.3.rs-2625841/v1
https://doi.org/10.21203/rs.3.rs-2625841/v1
Autor:
David C. Henshall, Alexis Arzimanoglou, Stefanie Dedeurwaerdere, Renzo Guerrini, Sergiusz Jozwiak, Merab Kokaia, Holger Lerche, Asla Pitkänen, Philippe Ryvlin, Michele Simonato, Sanjay M. Sisodiya
Publikováno v:
Epilepsy research. 189
Collaboration is essential to the conduct of basic, applied and clinical research and its translation into the technologies and treatments urgently needed to improve the lives of people living with brain diseases and the health professionals who care
Autor:
Daniele Bertoglio, Halima Amhaoul, Annemie Van Eetveldt, Ruben Houbrechts, Sebastiaan Van De Vijver, Idrish Ali, Stefanie Dedeurwaerdere
Publikováno v:
Frontiers in Neurology, Vol 8 (2017)
The aim of epilepsy models is to investigate disease ontogenesis and therapeutic interventions in a consistent and prospective manner. The kainic acid-induced status epilepticus (KASE) rat model is a widely used, well-validated model for temporal lob
Externí odkaz:
https://doaj.org/article/06e2af08c66346ceb477c4b4003f3559