Zobrazeno 1 - 10 of 870 pro vyhledávání: '"Stefanich E"'
1
Akademický článek
Sialic Acid Mediated Endothelial and Hepatic Uptake: A Mechanism based Mathematic Model Elucidating the Complex Pharmacokinetics and Pharmacodynamics of Efmarodocokin Alfa, a Variably Glycosylated Fusion Protein.
Autor: Tao X; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Sukumaran S; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA; Now at Janssen: Pharmaceutical Companies of Johnson & Johnson, 1125 Trenton-Harbourton Road, Titusville, NJ 08560, USA., Sperinde G; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Liu C; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Beardsley MI; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Day P; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Kalo M; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Ayewoh E; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Cai H; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Wang Y; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA; Now at Gilead Sciences, Inc, 333 Lakeside Drive. Foster City, CA 94404, USA., Jun I; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA; Now at University of Florida, Gainesville, FL 32611, USA., Hirst K; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Nguyen V; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Chung S; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Lee D; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Lekkerkerker A; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Stefanich E; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA. Electronic address: stefanich.eric@gene.com.
Publikováno v: Journal of pharmaceutical sciences [J Pharm Sci] 2024 Jul; Vol. 113 (7), pp. 1975-1986. Date of Electronic Publication: 2024 Mar 30.
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2
Akademický článek
Mini-PBPK-Based Population Model and Covariate Analysis to Assess the Complex Pharmacokinetics and Pharmacodynamics of RO7449135, an Anti-KLK5/KLK7 Bispecific Antibody in Cynomolgus Monkeys.
Autor: Cai H; Preclinical and Translational Pharmacokinetics and Pharmacodynamics, Genentech Inc., 1 DNA Way, South San Francisco, California, 94080, USA., Tao X; Preclinical and Translational Pharmacokinetics and Pharmacodynamics, Genentech Inc., 1 DNA Way, South San Francisco, California, 94080, USA., Shim J; BioAnalytical Sciences, Genentech Inc., 1 DNA Way, South San Francisco, California, 94080, USA., Bauer RN; OMNI Biomarker Development, Genentech Inc., 1 DNA Way, South San Francisco, California, 94080, USA., Bremer M; OMNI Biomarker Development, Genentech Inc., 1 DNA Way, South San Francisco, California, 94080, USA., Bu W; BioAnalytical Sciences, Genentech Inc., 1 DNA Way, South San Francisco, California, 94080, USA., LaMar J; BioAnalytical Sciences, Genentech Inc., 1 DNA Way, South San Francisco, California, 94080, USA., Basile R; BioAnalytical Sciences, Genentech Inc., 1 DNA Way, South San Francisco, California, 94080, USA., Dere E; Safety Assessment, Genentech Inc., 1 DNA Way, South San Francisco, California, 94080, USA., Nguyen T; Safety Assessment, Genentech Inc., 1 DNA Way, South San Francisco, California, 94080, USA., Laing S; Safety Assessment, Genentech Inc., 1 DNA Way, South San Francisco, California, 94080, USA., Chan P; Biochemical and Cellular Pharmacology, Genentech Inc., 1 DNA Way, South San Francisco, California, 94080, USA., Yi T; Discovery Immunology, Genentech Inc., 1 DNA Way, South San Francisco, California, 94080, USA., Koerber JT; Antibody Engineering, Genentech Inc., 1 DNA Way, South San Francisco, California, 94080, USA., Sperinde G; BioAnalytical Sciences, Genentech Inc., 1 DNA Way, South San Francisco, California, 94080, USA., Stefanich E; Preclinical and Translational Pharmacokinetics and Pharmacodynamics, Genentech Inc., 1 DNA Way, South San Francisco, California, 94080, USA. stefanich.eric@gene.com.
Publikováno v: The AAPS journal [AAPS J] 2023 Jun 23; Vol. 25 (4), pp. 64. Date of Electronic Publication: 2023 Jun 23.
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3
Akademický článek
First-In-Human Phase I Study of the OX40 Agonist MOXR0916 in Patients with Advanced Solid Tumors.
Autor: Kim TW; Asan Medical Center, University of Ulsan, Seoul, Korea., Burris HA; Sarah Cannon Research Institute, Nashville, Tennessee., de Miguel Luken MJ; START-CIOCC, Hosp. HM Sanchinarro, Madrid, Spain., Pishvaian MJ; Johns Hopkins University School of Medicine, Washington, DC., Bang YJ; Seoul National University College of Medicine, Seoul, Korea., Gordon M; HonorHealth Research Institute, Scottsdale, Arizona., Awada A; Jules Bordet Institute, Brussels, Belgium., Camidge DR; University of Colorado Anschutz Medical Campus, Aurora, Colorado., Hodi FS; Dana-Farber Cancer Institute, Boston, Massachusetts., McArthur GA; Sir Peter MacCallum Department of Oncology, University of Melbourne, Victoria, Australia., Miller WH; Jewish General Hospital and Segal Cancer Centre, McGill University, Montréal, Canada., Cervantes A; Biomedical Research Institute INCLIVA, University of Valencia, Valencia Spain., Chow LQ; University of Washington, Seattle, Washington., Lesokhin AM; Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Medical College, New York, New York., Rutten A; GasthuisZusters Antwerpen Sint-Augustinus, Antwerp, Belgium., Sznol M; Yale School of Medicine, New Haven, Connecticut., Rishipathak D; Genentech, Inc., South San Francisco, California., Chen SC; Genentech, Inc., South San Francisco, California., Stefanich E; Genentech, Inc., South San Francisco, California., Pourmohamad T; Genentech, Inc., South San Francisco, California., Anderson M; Genentech, Inc., South San Francisco, California., Kim J; Genentech, Inc., South San Francisco, California., Huseni M; Genentech, Inc., South San Francisco, California., Rhee I; Genentech, Inc., South San Francisco, California., Siu LL; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2022 Aug 15; Vol. 28 (16), pp. 3452-3463.
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4
Akademický článek
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5
Akademický článek
Effect of Integrin Blockade on Experimental Spondyloarthritis.
Autor: Yau, Enoch1 (AUTHOR) enoch.yau@alumni.utoronto.ca, Lim, Melissa1 (AUTHOR), Qaiyum, Zoya1 (AUTHOR), Boroojeni, Shaghayegh Foroozan1 (AUTHOR), Tang, Michael1 (AUTHOR), Pacheco, Addison1 (AUTHOR), Tavasolian, Fataneh1 (AUTHOR), Inman, Robert D.1,2 (AUTHOR) robert.inman@uhn.ca
Publikováno v: Biomolecules (2218-273X). Nov2024, Vol. 14 Issue 11, p1386. 15p.
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6
Akademický článek
An integrated approach for characterizing immunogenic responses toward a bispecific antibody.
Autor: Cohen S; Department of BioAnalytical Sciences, Genentech Inc, South San Francisco, CA, USA., Chung S; Department of BioAnalytical Sciences, Genentech Inc, South San Francisco, CA, USA., Spiess C; Department of Antibody Engineering, Genentech Inc, South San Francisco, CA, USA., Lundin V; Department of Protein Analytical Chemistry, Genentech Inc, South San Francisco, CA, USA., Stefanich E; Genentech Inc, South San Francisco, CA, USA., Laing ST; Department of Safety Assessment, Genentech Inc, South San Francisco, CA, USA., Clark V; Department of Safety Assessment, Genentech Inc, South San Francisco, CA, USA., Brumm J; Department of Biostatistics, Genentech Inc, South San Francisco, CA, USA., Zhou Y; Department of BioAnalytical Sciences, Genentech Inc, South San Francisco, CA, USA., Huang C; Department of BioAnalytical Sciences, Genentech Inc, South San Francisco, CA, USA., Guerrero J; Department of BioAnalytical Sciences, Genentech Inc, South San Francisco, CA, USA., Myneni S; Department of BioAnalytical Sciences, Genentech Inc, South San Francisco, CA, USA., Yadav R; Genentech Inc, South San Francisco, CA, USA., Siradze K; Department of BioAnalytical Sciences, Genentech Inc, South San Francisco, CA, USA., Peng K; Department of BioAnalytical Sciences, Genentech Inc, South San Francisco, CA, USA.
Publikováno v: MAbs [MAbs] 2021 Jan-Dec; Vol. 13 (1), pp. 1944017.
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7
Akademický článek
Mitigating the risk of cytokine release syndrome in a Phase I trial of CD20/CD3 bispecific antibody mosunetuzumab in NHL: impact of translational system modeling.
Autor: Hosseini I; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Gadkar K; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Stefanich E; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Li CC; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Sun LL; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Chu YW; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Ramanujan S; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA. ramanujan.saroja@gene.com.
Publikováno v: NPJ systems biology and applications [NPJ Syst Biol Appl] 2020 Aug 28; Vol. 6 (1), pp. 28. Date of Electronic Publication: 2020 Aug 28.
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9
Akademický článek
促血小板生成素调控慢性肝病患者血小板的作用及其 临床应用.
Autor: 皮赛男1 pisainan@sysush.com, 李亮2, 杨默2, 陈友鹏1 chenyoupeng@sysush.com
Publikováno v: Journal of New Medicine. Sep2024, Vol. 55 Issue 9, p745-750. 6p.
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