Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Stefaniak Emma Jayne"'
Autor:
Stephen Stokes, Patrick C. Mahon, Alan D. Robertson, Jalanie D’Alessandro, Paul Webb, Charles Parry, Lisa Baker, Natalia Matassova, Nicholas G. M. Davies, Sean McKenna, Andrew Massey, Rachel Parsons, Yikang Wang, Macias Alba, Paul Brough, Ben Davis, Michael Wood, Simon Bedford, Jonathan D. Moore, Christopher J. Northfield, Loic le Strat, Stephen D. Roughley, Daniel Maddox, Seema Chavda, James Brooke Murray, Allan E. Surgenor, Johannes W. G. Meissner, Terry Shaw, Heather Simmonite, Stefaniak Emma Jayne, Victoria Chell, Neil Whitehead, Kirsten Brown
Publikováno v:
Journal of medicinal chemistry. 60(6)
Libraries of nonpurified resorcinol amide derivatives were screened by surface plasmon resonance (SPR) to determine the binding dissociation constant (off-rate, kd) for compounds binding to the pyruvate dehydrogenase kinase (PDHK) enzyme. Parallel of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb5f231f5660155f00b4666296b0e799
https://pubmed.ncbi.nlm.nih.gov/28199108
https://pubmed.ncbi.nlm.nih.gov/28199108
Autor:
Sean McKenna, Andrew Massey, Lisa Baker, K Benwell, Heather Simmonite, Teresa Brooks, Michael Wood, Stephen Stokes, Nicolas Foloppe, Andrea Fiumana, Paul Webb, Stefaniak Emma Jayne, Christopher J. Northfield, Macias Alba, Zoe Daniels, Daniel Maddox, Helen Browne, Joanne Wayne, Christopher John Graham, Stuart C. Ray
Publikováno v:
Molecular Cancer Therapeutics. 17:B163-B163
On sustaining damage to their DNA, cells employ a sophisticated mechanism of detection and repair, termed the DNA damage response (DDR). As a critical component of the DDR and G2/M checkpoint, Chk1 kinase represents an attractive target for cancer th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4ad7ce30c29670a74658952948678e4
https://doi.org/10.1158/1535-7163.targ-17-b163
https://doi.org/10.1158/1535-7163.targ-17-b163