Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Stefania Zimbone"'
Autor:
Stefania Zimbone, Valeria Romanucci, Armando Zarrelli, Maria Laura Giuffrida, Michele F. M. Sciacca, Valeria Lanza, Tiziana Campagna, Ludovica Maugeri, Salvatore Petralia, Grazia Maria Letizia Consoli, Giovanni Di Fabio, Danilo Milardi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract We investigate the therapeutic potential of Aloin A and Aloin B, two natural compounds derived from Aloe vera leaves, focusing on their neuroprotective and anticancer properties. The structural differences between these two epimers suggest t
Externí odkaz:
https://doaj.org/article/e7a371d732a4411d8c584e6af72d7013
Autor:
Andrea Magrì, Cristiana Lucia Rita Lipari, Pierpaolo Risiglione, Stefania Zimbone, Francesca Guarino, Antonella Caccamo, Angela Messina
Publikováno v:
Cell Death and Disease, Vol 14, Iss 2, Pp 1-10 (2023)
Abstract Mitochondrial dysfunction and the loss of mitophagy, aimed at recycling irreversibly damaged organelles, contribute to the onset of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease affecting spinal cord motor neurons. I
Externí odkaz:
https://doaj.org/article/e7e702e2f40c438eb047d99399d3e8d6
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 12456 (2023)
Heat shock protein 60 (Hsp60) is a member of the chaperonin family of heat shock proteins (HSPs), primarily found in the mitochondrial matrix. As a molecular chaperone, Hsp60 plays an essential role in mediating protein folding and assembly, and toge
Externí odkaz:
https://doaj.org/article/5de32e2ac82e45ae949e9706c70b0d5d
Autor:
Mariacristina Nicolosi, Francesco Bellia, Maria Laura Giuffrida, Stefania Zimbone, Valentina Oliveri, Graziella Vecchio
Publikováno v:
Results in Chemistry, Vol 3, Iss , Pp 100230- (2021)
Drugs that may regulate lipid metabolism and lower cholesterol, such as statins (drugs that reduce de novo cholesterol synthesis) or cyclodextrins (that promote cholesterol removal), are currently investigated as potential therapeutics for neuronal d
Externí odkaz:
https://doaj.org/article/5780f7be407d44f98a532a4621750f0e
Publikováno v:
Life, Vol 11, Iss 11, p 1256 (2021)
Brain-derived neurotrophic factor (BDNF) represents one of the most widely studied neurotrophins because of the many mechanisms in which it is involved. Among these, a growing body of evidence indicates BDNF as a pleiotropic signaling molecule and un
Externí odkaz:
https://doaj.org/article/635e84d7a21343ab9035c596acfaf436
Autor:
Andrea Magrì, Pierpaolo Risiglione, Antonella Caccamo, Beatrice Formicola, Marianna Flora Tomasello, Cristina Arrigoni, Stefania Zimbone, Francesca Guarino, Francesca Re, Angela Messina
Publikováno v:
Biomedicines, Vol 9, Iss 8, p 948 (2021)
Mutations in Cu/Zn Superoxide Dismutase (SOD1) gene represent one of the most common causes of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disorder that specifically affects motor neurons (MNs). The dismutase-active SOD1 G93A mutan
Externí odkaz:
https://doaj.org/article/cfcc818ebf574fc0873743fe267cd71b
Autor:
Patrizia Di Pietro, Stefania Zimbone, Giulia Grasso, Diego La Mendola, Damien Cossement, Rony Snyders, Cristina Satriano
Publikováno v:
Applied Sciences, Vol 11, Iss 14, p 6333 (2021)
In this work, nanobiohybrids of plasmonic gold nanoparticles (AuNP, anti-angiogenic) and a peptide mimicking the vascular endothelial growth factor (VEGF, pro-angiogenic) were assembled and scrutinized in terms of physicochemical characterization, in
Externí odkaz:
https://doaj.org/article/07b042e479e64de8ac0305c34a4e75ac
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 24, p 9343 (2020)
The antiangiogenic activity of the H/P domain of histidine–proline-rich glycoprotein is mediated by its binding with tropomyosin, a protein exposed on endothelial cell-surface during the angiogenic switch, in presence of zinc ions. Although it is k
Externí odkaz:
https://doaj.org/article/96ecf471d73b4f71b5f62b0d7e69dcec
Autor:
Stefania Zimbone, Anna M. Santoro, Diego La Mendola, Chiara Giacomelli, Maria L. Trincavelli, Marianna F. Tomasello, Danilo Milardi, Sara García-Viñuales, Michele F. M. Sciacca, Claudia Martini, Giulia Grasso
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 8, p 2866 (2020)
Copper plays an important role as a regulator in many pathologies involving the angiogenesis process. In cancerogenesis, tumor progression, and angiogenic diseases, copper homeostasis is altered. Although many details in the pathways involved are sti
Externí odkaz:
https://doaj.org/article/beb2ed258431484e9683920cf47b4f6a
Autor:
Stefania Zimbone, Maria Laura Giuffrida, Giuseppina Sabatino, Giuseppe Di Natale, Rita Tosto, Grazia M. L. Consoli, Danilo Milardi, Giuseppe Pappalardo, Michele F.M. Sciacca
Publikováno v:
ACS Chemical Neuroscience. 14:1126-1136
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb5f22a557fa8ad73ef90350a3bdda9c
https://doi.org/10.1021/acschemneuro.2c00720
https://doi.org/10.1021/acschemneuro.2c00720