Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Stefania Saccoccio"'
Autor:
Stefania Saccoccio, Sergio Valente, Stefano Tomassi, Enzo Agostinelli, Antonello Mai, G. Tempera
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2011, 54 (23), pp.8228-32. ⟨10.1021/jm201011x⟩
Journal of Medicinal Chemistry, American Chemical Society, 2011, 54 (23), pp.8228-32. ⟨10.1021/jm201011x⟩
Monoamine oxidases (MAOs) are involved in various psychiatric and neurodegenerative disorders; hence, MAO inhibitors are useful agents in the therapy of Parkinson's disease, Alzheimer's dementia, and depression syndrome. Herein we report a novel seri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e74b872a3f56d89c91996bd1915bcde6
https://doi.org/10.1021/jm201011x
https://doi.org/10.1021/jm201011x
Autor:
Antonio Toninello, Silvia Grancara, Vito Di Noto, Pamela Martinis, Lisa Dalla Via, Stefania Saccoccio, Valentina Battaglia, Marcantonio Bragadin, Maria Angelica Grillo, Enzo Agostinelli
Publikováno v:
Amino Acids. 42:761-768
Agmatine, a divalent diamine with two positive charges at physiological pH, is transported into the matrix of liver mitochondria by an energy-dependent mechanism, the driving force of which is the electrical membrane potential. Its binding to mitocho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8d5c4a065140faeca7a7efecda00460
https://doi.org/10.1007/s00726-011-0992-1
https://doi.org/10.1007/s00726-011-0992-1
Autor:
Stefania Saccoccio, Antonio Toninello, Silvia Grancara, Enzo Agostinelli, Valentina Battaglia, Joseph Satriano
Publikováno v:
Amino Acids. 38:431-437
The arginine metabolite agmatine is able to protect brain mitochondria against the drop in energy capacity by the Ca(2+)-dependent induction of permeability transition (MPT) in rat brain mitochondria. At normal levels, the amine maintains the respira
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dd0956e6bd8b5763a79c8f5ddd7d4af
https://doi.org/10.1007/s00726-009-0402-0
https://doi.org/10.1007/s00726-009-0402-0
Autor:
Valentina Battaglia, Stefania Saccoccio, Alessandra Cona, Rodolfo Federico, G. Tempera, Nikenza Viceconte, Antonio Toninello, Enzo Agostinelli, Paraskevi Tavladoraki
Publikováno v:
Amino Acids
Amino Acids, Springer Verlag, 2012, 42 (2-3), pp.411-26. ⟨10.1007/s00726-011-1012-1⟩
Amino Acids, Springer Verlag, 2012, 42 (2-3), pp.411-26. ⟨10.1007/s00726-011-1012-1⟩
International audience; Metabolism of polyamines spermidine and spermine, and their diamine precursor, putrescine, has been a target for antineoplastic therapy since these naturally occurring alkyl amines were found essential for normal mammalian cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7313c60c002fcfa6056df2d5eb33d634
http://hdl.handle.net/11573/434522
http://hdl.handle.net/11573/434522
Autor:
G. Tempera, Silvia Grancara, Stefania Saccoccio, Enzo Agostinelli, Antonio Toninello, Valentina Battaglia, Nikenza Viceconte, Roberto Stevanato
The polyamines spermine, spermidine and putrescine are ubiquitous cell components. These molecules are substrates of a class of enzymes that includes monoamine oxidases, diamine oxidases, polyamine oxidases and copper-containing amine oxidases. Amine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b4eeee6bf36bdb9de637b32203f1cb7
http://hdl.handle.net/11573/74864
http://hdl.handle.net/11573/74864
Autor:
Mariana Nalli, Ana Batista-de-Carvalho, Stefania Saccoccio, Giorgio Ortar, Eris Bidollari, Enrico Morera, Enzo Agostinelli, G. Tempera, Nikenza Viceconte
Publikováno v:
BMC Proceedings
Polyamines are necessary for cell proliferation and are detected at higher concentrations in most tumor tissues. Bovine serum amine oxidase (BSAO) can generate in situ cytotoxic products such as H2O2 and aldehydes from oxidation of polyamines, as a n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ae656eeed3f2d4fecb14867641fbed
http://europepmc.org/articles/PMC3255028
http://europepmc.org/articles/PMC3255028
Autor:
Sergio Valente, Stefano Tomassi, Giampiero Tempera, Stefania Saccoccio, Enzo Agostinelli, Antonello Mai
Publikováno v:
Journal of Medicinal Chemistry; Dec2011, Vol. 54 Issue 23, p8228-8232, 5p