Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Stefania Rigacci"'
Autor:
Elisabetta Borchi, Valentina Bargelli, Valentina Guidotti, Andrea Berti, Massimo Stefani, Chiara Nediani, Stefania Rigacci
Publikováno v:
Redox Biology, Vol 2, Iss C, Pp 114-122 (2014)
The presence of amyloid aggregates of human islet amyloid polypeptide (hIAPP), a hallmark of type 2 diabetes, contributes to pancreatic β-cell impairment, where oxidative stress plays a key role. A contribution of NADPH oxidase to reactive oxygen sp
Externí odkaz:
https://doaj.org/article/41bc3ec42b2a44ebae2180cd5499a64a
Autor:
Massimo Stefani, Stefania Rigacci
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 6, Pp 12411-12457 (2013)
Amyloid aggregation is a hallmark of several degenerative diseases affecting the brain or peripheral tissues, whose intermediates (oligomers, protofibrils) and final mature fibrils display different toxicity. Consequently, compounds counteracting amy
Externí odkaz:
https://doaj.org/article/b88fa19e3b0c4a2fb40cd1dfe8af4abc
Autor:
Cristina Grossi, Stefania Rigacci, Stefano Ambrosini, Teresa Ed Dami, Ilaria Luccarini, Chiara Traini, Paola Failli, Andrea Berti, Fiorella Casamenti, Massimo Stefani
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71702 (2013)
The claimed beneficial effects of the Mediterranean diet include prevention of several age-related dysfunctions including neurodegenerative diseases and Alzheimer-like pathology. These effects have been related to the protection against cognitive dec
Externí odkaz:
https://doaj.org/article/ee980c16a30c4ec89cf36b9cbb5a6035
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58893 (2013)
The presence of amyloid aggregates of the 42 amino acid peptide of amyloid beta (Aβ42) in the brain is the characteristic feature of Alzheimer's disease (AD). Amyloid beta (Aβ deposition is also found in muscle fibers of individuals affected by inc
Externí odkaz:
https://doaj.org/article/5431920070fe44bc9b0233ceb5ae9a19
Autor:
Stefania Rigacci, Massimo Stefani
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 6, p 843 (2016)
The increasing interest in the Mediterranean diet hinges on its healthy and anti-ageing properties. The composition of fatty acids, vitamins and polyphenols in olive oil, a key component of this diet, is considered a key feature of its healthy proper
Externí odkaz:
https://doaj.org/article/aa6fe9204f18406e9382bee5fc310231
Autor:
Monica Bucciantini, Moufida Saidani Tounsi, Manuela Leri, Borhane Mahjoub, El Akrem Hayouni, Massimo Stefani, Zohra Dhouafli, Stefania Rigacci, Wissem Aidi Wannes
Publikováno v:
Industrial Crops and Products. 111:823-833
The aggregation and deposition of misfolded β-amyloid peptide (Aβ42) is a consistent pathological hallmark of Alzheimer Disease (AD). Mounting pieces of evidence indicate that the auto-assembly of As42 into toxic oligomers and fibrillar aggregates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b099034bb7d72b24e53edc3386d9669f
https://doi.org/10.1016/j.indcrop.2017.11.045
https://doi.org/10.1016/j.indcrop.2017.11.045
Autor:
Ilaria Luccarini, Giancarlo la Marca, Massimo Stefani, Fiorella Casamenti, Anna Maria Pugliese, Elisabetta Coppi, Stefania Rigacci, Cristina Grossi, Daniela Pantano, Andrea Berti, Teresa Ed Dami
Publikováno v:
Neurobiology of Aging. 36:648-663
Amyloid-ß (Aß) fragments, oligomeric Aß aggregates, and pyroglutamylated-Aß peptides, as well as epigenetic mechanisms and autophagy dysfunction all appear to contribute in various ways to Alzheimer's disease progression. We previously showed tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55d53df317fca5eedbb4285ebe4702d9
https://doi.org/10.1016/j.neurobiolaging.2014.08.029
https://doi.org/10.1016/j.neurobiolaging.2014.08.029
Autor:
SE. Anderson, Carmem Luiza Sartorio, Claire Wilson, Jenny James, Daniel Johnson, Roberto Papait, Daniel Bromage, R.M. Krams, Caterina Miceli, Sandra Donnini, Erika Terzuoli, Federica Finetti, Marina Ziche, Stefania Rigacci, Valentina Bargelli, Carla Giordano, Laura Raimondi, Chiara Nediani, R.M. Pedrigi, Z. Kis, Jack Pickard, Xavier Rossello, Niall Burke, Oliver Ziff, Derek Yellon, Sean Davidson, Christina Pagiatakis, Francesca Rusconi, Pierluigi Carullo, Simone Serio, Gianluigi Condorelli, S Deckx, M. Rienks, P. Carai, E. Van Deel, J. Van Der Velden, K.R. Sipido, S Heymans, A. Papageorgiou, Jonathan Humphries, Ann Canfield, Martin Humphries, Gloria Bertoli, Davide Lazzeroni, Ornella Rimoldi, Alessandra Esposito, Giovanni Peretto, Anna Damascelli, Francesco De Cobelli, Ottavio Alfieri, Paolo Guido Camici, GL. Smith, RC. Myles
Publikováno v:
Cardiovascular Research. 111:S117-S119
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cea8cb4da56ba564ded80af975b70e0
https://doi.org/10.1093/cvr/cvw143
https://doi.org/10.1093/cvr/cvw143
Autor:
Massimo Stefani, Stefania Rigacci
Publikováno v:
Expert Review of Neurotherapeutics. 15:41-52
A common molecular feature of amyloid neurodegenerative diseases is the unfolding/misfolding of specific proteins/peptides which consequently become prone to aggregate into toxic assemblies and deposits that are the key histopathological trait of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15c276d033b9fcbb9c7e7d3b02f30a8a
https://doi.org/10.1586/14737175.2015.986101
https://doi.org/10.1586/14737175.2015.986101
Autor:
Massimo Stefani, Stefania Rigacci
Publikováno v:
BioFactors. 40:482-493
Mediterranean and Asian diets are currently considered as the most healthy traditional feeding habits effective against risk of age-associated, particularly cardiovascular and neurodegenerative, diseases. A common feature of these two regimens is the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0042840238e6427613f2ecb3f6a53d1e
https://doi.org/10.1002/biof.1171
https://doi.org/10.1002/biof.1171