Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Stefania Pieroni"'
Autor:
Nicola Di-Iacovo, Simona Ferracchiato, Stefania Pieroni, Damiano Scopetti, Marilena Castelli, Danilo Piobbico, Luca Pierucci, Marco Gargaro, Davide Chiasserini, Giuseppe Servillo, Maria Agnese Della-Fazia
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4600 (2024)
TP53 mutations are prevalent in various cancers, yet the complexity of apoptotic pathway deregulation suggests the involvement of additional factors. HOPS/TMUB1 is known to extend the half-life of p53 under normal and stress conditions, implying a re
Externí odkaz:
https://doaj.org/article/f15a8450055041b096aa8f3ddc779a49
Autor:
Nicola Di-Iacovo, Stefania Pieroni, Danilo Piobbico, Marilena Castelli, Damiano Scopetti, Simona Ferracchiato, Maria Agnese Della-Fazia, Giuseppe Servillo
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1176 (2023)
The physiological importance of the liver is demonstrated by its unique and essential ability to regenerate following extensive injuries affecting its function. By regenerating, the liver reacts to hepatic damage and thus enables homeostasis to be re
Externí odkaz:
https://doaj.org/article/ed986642b37148c48fcd24ba9150fcd0
Autor:
Frank L. van de Veerdonk, Giorgia Renga, Marilena Pariano, Marina M. Bellet, Giuseppe Servillo, Francesca Fallarino, Antonella De Luca, Rossana G. Iannitti, Danilo Piobbico, Marco Gargaro, Giorgia Manni, Fiorella D’Onofrio, Claudia Stincardini, Luigi Sforna, Monica Borghi, Marilena Castelli, Stefania Pieroni, Vasileios Oikonomou, Valeria R. Villella, Matteo Puccetti, Stefano Giovagnoli, Roberta Galarini, Carolina Barola, Luigi Maiuri, Maria Agnese Della Fazia, Barbara Cellini, Vincenzo Nicola Talesa, Charles A. Dinarello, Claudio Costantini, Luigina Romani
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 2 (2022)
Autophagy selectively degrades aggregation-prone misfolded proteins caused by defective cellular proteostasis. However, the complexity of autophagy may prevent the full appreciation of how its modulation could be used as a therapeutic strategy in dis
Externí odkaz:
https://doaj.org/article/37bfe8f4acef4696892b52f446b0f266
Autor:
Michela Franchini, Stefania Pieroni, Francesca Denoth, Marco Scalese Urciuoli, Emanuela Colasante, Massimiliano Salvatori, Giada Anastasi, Cinzia Katia Frontignano, Elena Dogliotti, Sofia Vidali, Edgardo Montrucchio, Sabrina Molinaro, Tommaso Susini, Jacopo Nori Cucchiari
Publikováno v:
Cancers, Vol 14, Iss 23, p 5801 (2022)
Breast cancer (BC) has overtaken lung cancer as the most common cancer in the world and the projected incidence rates show a further increase. Early detection through population screening remains the cornerstone of BC control, but a progressive chang
Externí odkaz:
https://doaj.org/article/30eb1e1dcf704986a4e1127a67257612
Autor:
Stefania Pieroni, Marilena Castelli, Danilo Piobbico, Simona Ferracchiato, Damiano Scopetti, Nicola Di-Iacovo, Maria Agnese Della-Fazia, Giuseppe Servillo
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 14480 (2022)
A cancer outcome is a multifactorial event that comes from both exogenous injuries and an endogenous predisposing background. The healthy state is guaranteed by the fine-tuning of genes controlling cell proliferation, differentiation, and development
Externí odkaz:
https://doaj.org/article/9d4ccc7461164545aa18456d98b26a7c
Autor:
Simona Ferracchiato, Nicola Di-Iacovo, Damiano Scopetti, Danilo Piobbico, Marilena Castelli, Stefania Pieroni, Marco Gargaro, Giorgia Manni, Stefano Brancorsini, Maria Agnese Della-Fazia, Giuseppe Servillo
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13, p 7186 (2021)
HOPS is a ubiquitin-like protein implicated in many aspects of cellular function including the regulation of mitotic activity, proliferation, and cellular stress responses. In this study, we focused on the complex relationship between HOPS and the tu
Externí odkaz:
https://doaj.org/article/edf69071c86e48ec9c8702e3234ca0ed
Autor:
Marilena Pariano, Stefania Pieroni, Antonella De Luca, Rossana G. Iannitti, Monica Borghi, Matteo Puccetti, Stefano Giovagnoli, Giorgia Renga, Fiorella D’Onofrio, Marina M. Bellet, Claudia Stincardini, Maria Agnese Della-Fazia, Giuseppe Servillo, Frank L. van de Veerdonk, Claudio Costantini, Luigina Romani
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12, p 6531 (2021)
Inflammasomes are powerful cytosolic sensors of environmental stressors and are critical for triggering interleukin-1 (IL-1)-mediated inflammatory responses. However, dysregulation of inflammasome activation may lead to pathological conditions, and t
Externí odkaz:
https://doaj.org/article/f10bebaaca994d7398b3e7c72cdd8f0c
Autor:
Marina Maria Bellet, Claudia Stincardini, Claudio Costantini, Marco Gargaro, Stefania Pieroni, Marilena Castelli, Danilo Piobbico, Paolo Sassone-Corsi, Maria Agnese Della-Fazia, Luigina Romani, Giuseppe Servillo
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6, p 2974 (2021)
The circadian clock driven by the daily light–dark and temperature cycles of the environment regulates fundamental physiological processes and perturbations of these sophisticated mechanisms may result in pathological conditions, including cancer.
Externí odkaz:
https://doaj.org/article/258b7d2949f34c6f8ee5ac84a169db8f
Autor:
Michela Franchini, Stefania Pieroni, Arianna Cutilli, Michelangelo Caiolfa, Simone Naldoni, Sabrina Molinaro
Publikováno v:
Frontiers in Medicine, Vol 6 (2019)
Chronicity is the real challenge for public healthcare systems especially in relation to multi-morbidity. The growing demand for multidisciplinary care could be addressed by implementing integrated programs in the primary care field and facilitating
Externí odkaz:
https://doaj.org/article/b824a42a78674f6888184d1037e5548f
Publikováno v:
Frontiers in Public Health, Vol 6 (2018)
Modern medicine remains dependent on the accurate evaluation of a patient’s health state, recognizing that disease is a process that evolves over time and interacts with many factors unique to that patient. The CARPEDIEM project represents a concre
Externí odkaz:
https://doaj.org/article/4fe84fae2fdc49d9807c7ba48ee27a4b