Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Stefania Giacomello"'
Autor:
Lindsay A. Rutter, Matthew J. MacKay, Henry Cope, Nathaniel J. Szewczyk, JangKeun Kim, Eliah Overbey, Braden T. Tierney, Masafumi Muratani, Ben Lamm, Daniela Bezdan, Amber M. Paul, Michael A. Schmidt, George M. Church, Stefania Giacomello, Christopher E. Mason
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Common and rare alleles are now being annotated across millions of human genomes, and omics technologies are increasingly being used to develop health and treatment recommendations. However, these alleles have not yet been systematically cha
Externí odkaz:
https://doaj.org/article/432fef0373e34d608e1135e3084c96bc
Autor:
Lindsay A. Rutter, Henry Cope, Matthew J. MacKay, Raúl Herranz, Saswati Das, Sergey A. Ponomarev, Sylvain V. Costes, Amber M. Paul, Richard Barker, Deanne M. Taylor, Daniela Bezdan, Nathaniel J. Szewczyk, Masafumi Muratani, Christopher E. Mason, Stefania Giacomello
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Future multi-year crewed planetary missions will motivate advances in aerospace nutrition and telehealth. On Earth, the Human Cell Atlas project aims to spatially map all cell types in the human body. Here, we propose that a parallel Human C
Externí odkaz:
https://doaj.org/article/8437acf351cc4701911db4f7597c176b
Autor:
Yuvarani Masarapu, Egle Cekanaviciute, Zaneta Andrusivova, Jakub O. Westholm, Åsa Björklund, Robin Fallegger, Pau Badia-i-Mompel, Valery Boyko, Shubha Vasisht, Amanda Saravia-Butler, Samrawit Gebre, Enikő Lázár, Marta Graziano, Solène Frapard, Robert G. Hinshaw, Olaf Bergmann, Deanne M. Taylor, Douglas C. Wallace, Christer Sylvén, Konstantinos Meletis, Julio Saez-Rodriguez, Jonathan M. Galazka, Sylvain V. Costes, Stefania Giacomello
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Impairment of the central nervous system (CNS) poses a significant health risk for astronauts during long-duration space missions. In this study, we employed an innovative approach by integrating single-cell multiomics (transcriptomics and c
Externí odkaz:
https://doaj.org/article/e005e5c2fdd54d54a58a469fc7aa1cbf
Autor:
Hailey Sounart, Enikő Lázár, Yuvarani Masarapu, Jian Wu, Tibor Várkonyi, Tibor Glasz, András Kiss, Erik Borgström, Andrew Hill, Sefanit Rezene, Soham Gupta, Aleksandra Jurek, Anezka Niesnerová, Henrik Druid, Olaf Bergmann, Stefania Giacomello
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-28 (2023)
Abstract Technologies to study localized host–pathogen interactions are urgently needed. Here, we present a spatial transcriptomics approach to simultaneously capture host and pathogen transcriptome-wide spatial gene expression information from hum
Externí odkaz:
https://doaj.org/article/40ebc38f0ce841148f8dd664380d350a
Autor:
Hailey Sounart, Denis Voronin, Yuvarani Masarapu, Matthew Chung, Sami Saarenpää, Elodie Ghedin, Stefania Giacomello
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Several important human infectious diseases are caused by microscale-sized parasitic nematodes like filarial worms. Filarial worms have their own spatial tissue organization; to uncover this tissue structure, we need methods that can spatial
Externí odkaz:
https://doaj.org/article/c7fcc5fe57174f9cbfea6f78e053c549
Autor:
Vesna Grujčić, Sami Saarenpää, John Sundh, Bengt Sennblad, Benjamin Norgren, Meike Latz, Stefania Giacomello, Rachel A Foster, Anders F Andersson
Publikováno v:
PLoS ONE, Vol 19, Iss 1, p e0296672 (2024)
Single-cell transcriptomics has the potential to provide novel insights into poorly studied microbial eukaryotes. Although several such technologies are available and benchmarked on mammalian cells, few have been tested on protists. Here, we applied
Externí odkaz:
https://doaj.org/article/060865f271f340c1ba9c4f9913e88455
Autor:
Aránzazu Manzano, Silvio Weging, Daniela Bezdan, Joseph Borg, Thomas Cahill, Eugénie Carnero-Diaz, Henry Cope, Colleen S. Deane, Timothy Etheridge, Stefania Giacomello, Gary Hardiman, Natalie Leys, Pedro Madrigal, Felice Mastroleo, F. Javier Medina, Jakub Mieczkowski, Manuel A. Fernandez-Rojo, Keith Siew, Nathaniel J. Szewczyk, Stephen B. Walsh, Willian A. da Silveira, Raúl Herranz
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107289- (2023)
Summary: Following on from the NASA twins’ study, there has been a tremendous interest in the use of omics techniques in spaceflight. Individual space agencies, NASA’s GeneLab, JAXA's ibSLS, and the ESA-funded Space Omics Topical Team and the Int
Externí odkaz:
https://doaj.org/article/3031f2fe08944d85a84de26b43157091
Autor:
Christer Sylvén, Eva Wärdell, Agneta Månsson-Broberg, Eugenio Cingolani, Konstantinos Ampatzis, Ludvig Larsson, Åsa Björklund, Stefania Giacomello
Publikováno v:
iScience, Vol 26, Iss 1, Pp 105857- (2023)
Summary: Cardiomyocytes play key roles during cardiogenesis, but have poorly understood features, especially in prenatal stages. Here, we characterized human prenatal cardiomyocytes, 6.5–7 weeks post-conception, by integrating single-cell RNA seque
Externí odkaz:
https://doaj.org/article/777de29688124b63abc1e0d72dc36412
Autor:
Weipang Chang, Andrea Pedroni, Reinhard W. Köster, Stefania Giacomello, Konstantinos Ampatzis
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Purkinje cells are critically involved in processing the cerebellar functions by shaping and coordinating commands that they receive. Here, we demonstrate experimentally that in the adult zebrafish valvular part of the cerebellum, the Purkin
Externí odkaz:
https://doaj.org/article/40ae9461efb646e9bb8852178b005b29
Publikováno v:
iScience, Vol 25, Iss 9, Pp 104868- (2022)
In a broadening and more competitive space exploration landscape, playing at scale is necessary to obtain results. European researchers share their lessons learned on growing a research program where omics techniques can feed new knowledge, both fund
Externí odkaz:
https://doaj.org/article/bc277f68abaf41a2b1e19ccf6afca2a4