Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Stefania Gastaldi"'
Autor:
Andrea Bertotti, Livio Trusolino, Paolo M. Comoglio, Maria Flavia Di Renzo, Enzo Medico, Timothy Perera, Lorenzo Capussotti, Mauro Salizzoni, Mauro Risio, Bruno Torchio, Ezio David, Alberto Pisacane, Francesca Maione, Federica Gonella, Gianluca Paraluppi, Dimitrios Siatis, Paolo Massucco, Andrea Muratore, Dario Ribero, Stefania Gastaldi, Davide Corà, Claudio Isella, Francesco Sassi, Davide Torti, Francesco Galimi
Purpose: We determined the gene copy numbers for MET, for its transcriptional activator MACC1 and for its ligand hepatocyte growth factor (HGF) in liver metastases from colorectal carcinoma (mCRC). We correlated copy numbers with mRNA levels and expl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ae8fe43d8411ecb5e2655e5a49b5cc4
https://doi.org/10.1158/1078-0432.c.6518392.v1
https://doi.org/10.1158/1078-0432.c.6518392.v1
Autor:
Andrea Bertotti, Livio Trusolino, Paolo M. Comoglio, Maria Flavia Di Renzo, Enzo Medico, Timothy Perera, Lorenzo Capussotti, Mauro Salizzoni, Mauro Risio, Bruno Torchio, Ezio David, Alberto Pisacane, Francesca Maione, Federica Gonella, Gianluca Paraluppi, Dimitrios Siatis, Paolo Massucco, Andrea Muratore, Dario Ribero, Stefania Gastaldi, Davide Corà, Claudio Isella, Francesco Sassi, Davide Torti, Francesco Galimi
Supplementary Table S1 from Genetic and Expression Analysis of MET, MACC1, and HGF in Metastatic Colorectal Cancer: Response to Met Inhibition in Patient Xenografts and Pathologic Correlations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45f70b318cf6655fba43d6f03c896652
https://doi.org/10.1158/1078-0432.22441309
https://doi.org/10.1158/1078-0432.22441309
Autor:
Andrea Bertotti, Livio Trusolino, Paolo M. Comoglio, Maria Flavia Di Renzo, Enzo Medico, Timothy Perera, Lorenzo Capussotti, Mauro Salizzoni, Mauro Risio, Bruno Torchio, Ezio David, Alberto Pisacane, Francesca Maione, Federica Gonella, Gianluca Paraluppi, Dimitrios Siatis, Paolo Massucco, Andrea Muratore, Dario Ribero, Stefania Gastaldi, Davide Corà, Claudio Isella, Francesco Sassi, Davide Torti, Francesco Galimi
Supplementary Figure S1 from Genetic and Expression Analysis of MET, MACC1, and HGF in Metastatic Colorectal Cancer: Response to Met Inhibition in Patient Xenografts and Pathologic Correlations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0604942eef589830ae837c64b185d602
https://doi.org/10.1158/1078-0432.22441315
https://doi.org/10.1158/1078-0432.22441315
Autor:
Andrea Bertotti, Livio Trusolino, Paolo M. Comoglio, Maria Flavia Di Renzo, Enzo Medico, Timothy Perera, Lorenzo Capussotti, Mauro Salizzoni, Mauro Risio, Bruno Torchio, Ezio David, Alberto Pisacane, Francesca Maione, Federica Gonella, Gianluca Paraluppi, Dimitrios Siatis, Paolo Massucco, Andrea Muratore, Dario Ribero, Stefania Gastaldi, Davide Corà, Claudio Isella, Francesco Sassi, Davide Torti, Francesco Galimi
Supplementary Materials and Methods from Genetic and Expression Analysis of MET, MACC1, and HGF in Metastatic Colorectal Cancer: Response to Met Inhibition in Patient Xenografts and Pathologic Correlations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1950c633af7626b8c1ac3e539d667791
https://doi.org/10.1158/1078-0432.22441312
https://doi.org/10.1158/1078-0432.22441312
Autor:
Maria Flavia Di Renzo, Mauro Salizzoni, Lorenzo Capussotti, Stefania Gastaldi, Enzo Medico, Livio Trusolino, Timothy Perera, Alberto Pisacane, Davide Corà, Davide Torti, Gianluca Paraluppi, Paolo Massucco, Dimitrios Siatis, Andrea Bertotti, Francesco Galimi, Francesca Maione, Mauro Risio, Claudio Isella, Dario Ribero, Ezio David, Federica Gonella, Bruno Torchio, Paolo M. Comoglio, Andrea Muratore, Francesco Sassi
Publikováno v:
Clinical Cancer Research. 17:3146-3156
Purpose: We determined the gene copy numbers for MET, for its transcriptional activator MACC1 and for its ligand hepatocyte growth factor (HGF) in liver metastases from colorectal carcinoma (mCRC). We correlated copy numbers with mRNA levels and expl
Publikováno v:
The American Journal of Pathology. 173:289-299
Intravascular hemolysis results in the release of massive amounts of hemoglobin and heme into plasma, where they are rapidly bound by haptoglobin and hemopexin, respectively. Data from haptoglobin and hemopexin knockout mice have shown that both prot
Autor:
Paolo M. Comoglio, Paolo Accornero, Francesco Sassi, Stefania Gastaldi, Davide Torti, Carla Boccaccio, Matthew J. Smalley, Francesco Galimi, Andrea Bertotti, Giorgia Migliardi, Gemma Molyneux, Timothy Perera, Livio Trusolino
Basal-like breast cancer is an aggressive subtype of mammary carcinoma. Despite expressing basal markers, typical of mammary stem cells, this tumor has been proposed to originate from luminal progenitors, which are downstream of stem cells along the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cf23fc5019f6b70e74dd405d8531e6f
http://hdl.handle.net/2318/102410
http://hdl.handle.net/2318/102410
Autor:
Francesco Galimi, Andrea Bertotti, Stefania Gastaldi, Livio Trusolino, Davide Torti, Timothy Perera, Paolo M. Comoglio, Francesco Sassi
Publikováno v:
International Journal of Cancer; Vol 130
International Journal of Cancer
International Journal of Cancer
The MET oncogene is amplified in a fraction of human gastric carcinoma cell lines, with consequent overexpression and constitutive activation of the corresponding protein product, the Met tyrosine kinase receptor. This genetically driven hyperactivat
Autor:
Luana Benedetti, Elisabetta Zardini, Diego Franciotta, Angelo Schenone, Gianluigi Mancardi, Chiara Briani, Alessandro Beronio, Stefania Gastaldi, Sven Jarius
Background Antimyelin-associated glycoprotein (MAG) polyneuropathy is a slowly progressive distal form of mixed motor-sensory polyneuropathy that is scarcely responsive to conventional immunosuppressive therapy. Rituximab, a B-cell depleting antibody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eae8f3594beb45b8bd07671f0fe2108d
http://hdl.handle.net/11577/2422587
http://hdl.handle.net/11577/2422587
Autor:
Stefania Gastaldi, Francesco Galimi, Andrea Bertotti, Livio Trusolino, Cecilia Bracco, Flavia Girolami, Enzo Medico, Davide Torti, Paul Elvin, Paolo M. Comoglio
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 16(15)
Purpose: We examined whether inhibition of Src tyrosine kinase, a downstream effector of the MET oncogene, can hinder the malignant properties of gastric tumors dependent on Met for growth and survival. Experimental Design: Sensitivity to Src inhibit