Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Stefania Demuro"'
Autor:
Thibault Alle, Carmine Varricchio, Yuemang Yao, Bobby Lucero, Goodwell Nzou, Stefania Demuro, Megan Muench, Khoa D. Vuong, Killian Oukoloff, Anne-Sophie Cornec, Karol R. Francisco, Conor R. Caffrey, Virginia M.-Y. Lee, Amos B. Smith, Andrea Brancale, Kurt R. Brunden, Carlo Ballatore
Publikováno v:
Journal of medicinal chemistry, vol 66, iss 1
Microtubule (MT)-stabilizing 1,2,4-triazolo[1,5-a]pyrimidines (TPDs) hold promise as candidate therapeutics for Alzheimer's disease (AD) and other neurodegenerative conditions. However, depending on the choice of substituents around the TPD core, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eec72b970204417d9dd0cef026d13404
https://escholarship.org/uc/item/7zv2q880
https://escholarship.org/uc/item/7zv2q880
Autor:
Thibault, Alle, Carmine, Varricchio, Yuemang, Yao, Bobby, Lucero, Goodwell, Nzou, Stefania, Demuro, Megan, Muench, Khoa D, Vuong, Killian, Oukoloff, Anne-Sophie, Cornec, Karol R, Francisco, Conor R, Caffrey, Virginia M-Y, Lee, Amos B, Smith, Andrea, Brancale, Kurt R, Brunden, Carlo, Ballatore
Publikováno v:
Journal of medicinal chemistry.
Microtubule (MT)-stabilizing 1,2,4-triazolo[1,5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9084db790eae44cc8b39f79dbfec7759
https://pubmed.ncbi.nlm.nih.gov/36534051
https://pubmed.ncbi.nlm.nih.gov/36534051
Autor:
Stefania Demuro, Conall Sauvey, Shailesh K. Tripathi, Rita M.C. Di Martino, Da Shi, Jose A. Ortega, Debora Russo, Beatrice Balboni, Barbara Giabbai, Paola Storici, Stefania Girotto, Ruben Abagyan, Andrea Cavalli
Publikováno v:
Eur J Med Chem
The human kinome plays a crucial role in several pathways. Its dysregulation has been linked to diverse central nervous system (CNS)-related disorders with a drastic impact on the aging population. Among them, tauopathies, such as Alzheimer’s Disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::425bd610d2cf2d6174d4e69b12c56eac
https://escholarship.org/uc/item/6cs1z9zk
https://escholarship.org/uc/item/6cs1z9zk
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 9098, p 9098 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 9098, p 9098 (2021)
Protein kinases (PKs) have been recognized as central nervous system (CNS)-disease-relevant targets due to their master regulatory role in different signal transduction cascades in the neuroscience space. Among them, GSK-3β, FYN, and DYRK1A play a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b02dae5812319f6ef1c2efe8f2bde410
http://europepmc.org/articles/PMC8396491
http://europepmc.org/articles/PMC8396491