Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Stefania Bonatti"'
Autor:
Pier Alberto Benedetti, Stefania Bonatti, Fabio Morandi, Roberto Barale, Marcella Simili, Angelo Abbondandolo, Renata Del Carratore, Paola Menichini
Publikováno v:
Environmental and Molecular Mutagenesis. 46:164-173
Rapamycin induces chromosome malsegregation in mammalian cell lines and yeast. Previous studies indicate that the function impaired in ataxia-telangiectasia (A-T) patients is necessary for both the growth inhibition and the chromosome malsegregation
Autor:
G. Margarino, Stefania Bonatti, Paola Mereu, Valeria Delfino, Angelo Abbondandolo, Barbara Garzoglio, Gianluigi Casartelli, Marco Scala
Publikováno v:
Mutagenesis. 17:73-77
No single biomarker can predict the risk for malignant transformation of precancerous lesions of the head and neck. Micronucleus frequency, nuclear p53 accumulation and mitotic index were determined in proliferating basal cells using paraffin-embedde
Autor:
Franco Merlo, Marcella De Ferrari, Federico Valerio, Stefania Bonatti, Angelo Abbondandolo, Vincenzo Fontana, Elena Gallerani, Claudia Bolognesi
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 394:37-44
Traffic police workers, as a population exposed to urban atmosphere, were compared with a control population exposed to indoor air pollution levels. Sister chromatid exchanges (SCEs) as a biomarker of effect were measured in peripheral blood lymphocy
Autor:
Paolo Degan, Angelo Abbondandolo, Stefania Bonatti, Marco Peluso, Roberta Rabboni, Elena Gallerani, Claudia Bolognesi, Paola Roggieri
Publikováno v:
Journal of Agricultural and Food Chemistry. 45:1957-1962
Glyphosate (N-phosphonomethylglycine) is an effective herbicide acting on the synthesis of aromatic amino acids in plants. The genotoxic potential of this herbicide has been studied: the results available in the open literature reveal a weak activity
Autor:
Louis de Saint-Georges, Simona Pigullo, Paola Pellerano, Marcella Simili, Gaia Tavosanis, Stefania Bonatti, Laura Ottaggio
Publikováno v:
Mutagenesis. 12:313-319
N-6 dimethylaminopurine (6DMAP) has been shown to induce aberrant mitosis in different cell types including Chinese hamster fibroblasts (CHEF/18), The mechanism of action and the cellular targets, however, are still not clear, We showed previously th
Autor:
Stefano Bonassi, Stefania Bonatti, C. Sbrana, Angelo Abbondandolo, D. Gargano, L. Lastrucci, G. Angotzi, M. De Ferrari, L. Miligi, M. Artuso
Publikováno v:
Scopus-Elsevier
Earlier studies have produced evidence for an association between work-related styrene exposure and cytogenetic damage, while more recent studies have failed to show such an association. In the present study, chromosome aberrations (CA) and sister ch
Autor:
Giuseppe Arena, Angelo Abbondandolo, Paola Pellerano, Zita Cavalieri, Stefania Bonatti, Mattia Rocco, Klaus Sailer, Silvia Viaggi, Anna Aprile
Publikováno v:
Environmental and Molecular Mutagenesis. 26:226-233
It has been reported that exogenous alkylated purines, such as O6-methylguanine (O6meG), induce aneuploidy in mammalian cells. It is shown here that the aneugenic effect of O6meG, evidenced by its ability to induce micronuclei in rodent cells, is dep
Autor:
M. Simili, Laura Ottaggio, Simonetta Bozzo, Mariangela Miele, Francesca Moro, Angelo Abbondandolo, Stefania Bonatti
Publikováno v:
Carcinogenesis. 16:2435-2440
To answer the question whether the level of p53 expression also reflects the status of a cell, with reference to transformation and genome stability, we have examined, by immunocytochemistry, the presence of p53 protein in a number of cell types incl
Publikováno v:
Environmental and Molecular Mutagenesis. 21:349-356
N,N-Dimethylaniline (DMA, CAS No. 121-69-7) and N,N-dimethyl-p-toluidine (DMPT, CAS No. 99-97-8) belong to the N-dialkylaminoaromatics, a chemical class structurally alerting to DNA reactivity. Their applications may be industrial (dye and pesticide
Autor:
Silvana Simi, R. Del Carratore, L. Hauri, M. Campagna, Marcella Simili, Pascale Beffy, Stefania Bonatti
Publikováno v:
Mutagenesis. 18(5)
It has been shown that the ethylating agent diethylsulphate (DES) induces centromere-containing micronuclei with kinetics suggesting that molecules other than DNA could be targets. In quiescent Chinese hamster fibroblasts CHEF/18, O 6 -alkylated base