Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Stefania Colarusso"'
Publikováno v:
European Journal of Organic Chemistry. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b58c76de64ac5bb7c1017bf67ebbd19
https://doi.org/10.1002/ejoc.202201274
https://doi.org/10.1002/ejoc.202201274
Autor:
Gregory L. Adams, Parul S. Pall, Steven M. Grauer, Xiaoping Zhou, Jeanine E. Ballard, Marissa Vavrek, Richard L. Kraus, Pierre Morissette, Nianyu Li, Stefania Colarusso, Elisabetta Bianchi, Anandan Palani, Rebecca Klein, Christopher T. John, Deping Wang, Matthew Tudor, Andrew F. Nolting, Mirlinda Biba, Timothy Nowak, Alexey A. Makarov, Mikhail Reibarkh, Alexei V. Buevich, Wendy Zhong, Erik L. Regalado, Xiao Wang, Qi Gao, Aurash Shahripour, Yuping Zhu, Daniele de Simone, Tommaso Frattarelli, Nicolo’ Maria Pasquini, Paola Magotti, Roberto Iaccarino, Yuxing Li, Kelli Solly, Keun-Joong Lee, Weixun Wang, Feifei Chen, Haoyu Zeng, Jixin Wang, Hilary Regan, Rupesh P. Amin, Christopher P. Regan, Christopher S. Burgey, Darrell A. Henze, Chengzao Sun, David M. Tellers
Publikováno v:
Journal of Medicinal Chemistry. 65:485-496
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ecd04283fe1d38ba43c9ca77818a20e
https://doi.org/10.1021/acs.jmedchem.1c01570
https://doi.org/10.1021/acs.jmedchem.1c01570
Autor:
Georg Kempf, Ignacio Munoz-Sanjuan, Alexandros Patsilinakos, Matteo Andreini, Stefania Colarusso, Vincenzo Summa, Jesus Maria Ontoria Ontoria, Federica Ferrigno, Paola Fezzardi, Steven J. Harper, Leticia Toledo Sherman, Stefan Steinbacher, Ilaria Biancofiore, Esther Torrente, Martin Augustin, Elisabetta Bianchi, Larry Park, Alberto Bresciani, Robert Pacifici, Celia Dominguez
Publikováno v:
ACS Med Chem Lett
[Image: see text] The NRF2-ARE pathway is an intrinsic mechanism of defense against oxidative stress. Inhibition of the interaction between NRF2 and its main negative regulator KEAP1 is an attractive strategy toward neuroprotective agents. We report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::697530dc3724a96d48064e27557ca038
https://doi.org/10.1021/acsmedchemlett.9b00594
https://doi.org/10.1021/acsmedchemlett.9b00594
Autor:
Barbara Attenni, Salvatore Avolio, Stefania Colarusso, Savina Malancona, Steven Harper, Sergio Altamura, Uwe Koch, Frank Narjes
Publikováno v:
ARKIVOC, Vol 2006, Iss 7, Pp 479-495 (2006)
Externí odkaz:
https://doaj.org/article/6fd050884f1a467ca80c8d6a6e846ba6
Autor:
Stefania Colarusso, Federica Ferrigno, Simona Ponzi, Francesca Pavone, Immacolata Conte, Luigi Abate, Elisa Beghetto, Antonino Missineo, Jerome Amaudrut, Alberto Bresciani, Giacomo Paonessa, Licia Tomei, Christian Montalbetti, Elisabetta Bianchi, Carlo Toniatti, Jesus M. Ontoria
Publikováno v:
Bioorganicmedicinal chemistry. 57
Zika virus (ZIKV) is a member of the Flaviviridae family that can cause neurological disorders and congenital malformations. The NS2B-NS3 viral serine protease is an attractive target for the development of new antiviral agents against ZIKV. We repor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0680820a0134a770bbd82b788e7dda5a
https://pubmed.ncbi.nlm.nih.gov/35123179
https://pubmed.ncbi.nlm.nih.gov/35123179
Autor:
Matteo Andreini, Stefan Steinbacher, Antonino Missineo, Georg Kempf, Ignacio Munoz-Sanjuan, Licia Tomei, Vincenzo Summa, Tommaso Frattarelli, D. De Simone, Mauro Cerretani, Leticia Toledo-Sherman, Celia Dominguez, Martin Augustin, Elisabetta Bianchi, Daniele Moretti, Sara Tambone, Stefania Colarusso, Larry Park, Alberto Bresciani
Publikováno v:
Bioorganic & Medicinal Chemistry. 28:115738
Inhibition of KEAP1-NRF2 protein-protein interaction is considered a promising strategy to selectively and effectively activate NRF2, a transcription factor which is involved in several pathologies such as Huntington's disease (HD). A library of line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::489702ad5ac860849caf323775f152eb
https://doi.org/10.1016/j.bmc.2020.115738
https://doi.org/10.1016/j.bmc.2020.115738
Autor:
Jörg Habermann, Stefania Colarusso, Immacolata Conte, Marcello Di Filippo, Caterina Ercolani, Maria Cecilia Palumbi, Maria del Rosario Rico Ferreira, Simone Zaramella, Angela C. Mackay, Frank Narjes, Ian Stansfield
Publikováno v:
Synlett. 2011:1527-1532
The development of a scalable chiral synthesis for the HCV NS5B inhibitor MK-3281 is being reported. Several alternative routes were explored and are being described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b1088cc8404a4ef3095848cb2384440
https://doi.org/10.1055/s-0030-1260790
https://doi.org/10.1055/s-0030-1260790
Autor:
Fabrizio Fiore, Maria del Rosario Rico Ferreira, Barbara Attenni, Savina Malancona, Simona Ponzi, Jesus Maria Ontoria Ontoria, Jose Ignacio Martin Hernando, Stefania Di Marco, Michael Rowley, Frank Narjes, Stefania Colarusso, Sue Ellen Vignetti, Fabio Bonelli, Uwe Koch, Jörg Habermann, Nadia Gennari
Publikováno v:
ChemMedChem. 4:1695-1713
Infections caused by the hepatitis C virus (HCV) are a significant world health problem for which novel therapies are in urgent demand. The NS5B polymerase of HCV is responsible for the replication of viral RNA and has been a prime target in the sear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f153469e7aabaa8dda229fceffb28510
https://doi.org/10.1002/cmdc.200900184
https://doi.org/10.1002/cmdc.200900184
Autor:
Salvatore Avolio, Steven J. Harper, Frank Narjes, Savina Malancona, Sergio Altamura, Uwe Koch, Barbara Attenni, Stefania Colarusso
Publikováno v:
ARKIVOC, Vol 2006, Iss 7, Pp 479-495 (2006)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43e562ed1c30ea1e87e0dfdc0a4df125
https://www.arkat-usa.org/arkivoc-journal/browse-arkivoc/ark.5550190.0007.733
https://www.arkat-usa.org/arkivoc-journal/browse-arkivoc/ark.5550190.0007.733
Autor:
Sergio Altamura, Uwe Koch, Stefania Colarusso, Immacolata Conte, Savina Malancona, Raffaele De Francesco, Barbara Pacini, Marcello Di Filippo, Barbara Attenni, Licia Tomei, Claudia Giomini, Ilario Incitti, Steven R. Thomas, Victor G. Matassa, Frank Narjes, Steven Harper
Publikováno v:
Journal of Medicinal Chemistry. 49:1693-1705
Infections caused by hepatitis C virus (HCV) are a significant world health problem for which novel therapies are in urgent demand. The polymerase of HCV is responsible for the replication of viral RNA. We recently disclosed dihydroxypyrimidine carbo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c73ecb399ce0128e894160dcd7937d36
https://doi.org/10.1021/jm051064t
https://doi.org/10.1021/jm051064t