Zobrazeno 1 - 10
of 204
pro vyhledávání: '"Stefania, Mitola"'
Publikováno v:
Cells, Vol 13, Iss 16, p 1346 (2024)
Background: Recently, the substitution R1051Q in VEGFR2 has been described as a cancer-associated “gain of function” mutation. VEGFR2R1051Q phosphorylation is ligand-independent and enhances the activation of intracellular pathways and cell growt
Externí odkaz:
https://doaj.org/article/3eed6bccbdeb49e7a956c08d9041cf88
Autor:
Cosetta Ravelli, Michela Corsini, Anna Ventura, Mattia Domenichini, Elisabetta Grillo, Stefania Mitola
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0308231 (2024)
[This corrects the article DOI: 10.1371/journal.pone.0304172.].
Externí odkaz:
https://doaj.org/article/e0aaac8ddb4643dc845f65e3dc39a438
Autor:
Silvia Codenotti, Leonardo Sandrini, Delia Mandracchia, Luisa Lorenzi, Giovanni Corsetti, Maura Poli, Michela Asperti, Valentina Salvi, Daniela Bosisio, Eugenio Monti, Stefania Mitola, Luca Triggiani, Michele Guescini, Enrico Pozzo, Maurilio Sampaolesi, Stefano Gastaldello, Matteo Cassandri, Francesco Marampon, Alessandro Fanzani
Publikováno v:
Cancers, Vol 16, Iss 5, p 853 (2024)
Identifying the molecular mechanisms underlying radioresistance is a priority for the treatment of RMS, a myogenic tumor accounting for approximately 50% of all pediatric soft tissue sarcomas. We found that irradiation (IR) transiently increased phos
Externí odkaz:
https://doaj.org/article/a7f1ac91bda0420f8a0fc600fcc41b36
Akademický článek
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Publikováno v:
International Journal of Translational Medicine, Vol 1, Iss 3, Pp 163-174 (2021)
For many years the growth of solid tumors has been associated with their vascularization. The new vessels are needed to deliver oxygen and nutrients within the tumor mass. At the same time, these poorly stabilized vessels act as “Trojan horses” a
Externí odkaz:
https://doaj.org/article/29a9ddb2cd7a46c99fe578e9d09a028f
Autor:
Luca Mignani, Nicola Facchinello, Marco Varinelli, Elena Massardi, Natascia Tiso, Cosetta Ravelli, Stefania Mitola, Peter Schu, Eugenio Monti, Dario Finazzi, Giuseppe Borsani, Daniela Zizioli
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7108 (2023)
In vertebrates, two homologous heterotetrameric AP1 complexes regulate the intracellular protein sorting via vesicles. AP-1 complexes are ubiquitously expressed and are composed of four different subunits: γ, β1, μ1 and σ1. Two different complexe
Externí odkaz:
https://doaj.org/article/a4d583b476f24210bdd091760345bb72
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/6586dccdcf9440688471c1317f2c0538
Autor:
Francesco Ciccarese, Angela Grassi, Lorenza Pasqualini, Stefania Rosano, Alessio Noghero, Francesca Montenegro, Federico Bussolino, Barbara Di Camillo, Lorenzo Finesso, Gianna Maria Toffolo, Stefania Mitola, Stefano Indraccolo
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 3977-3986 (2020)
Interferon-α (IFN-α) comprises a family of 13 cytokines involved in the modulation of antiviral, immune, and anticancer responses by orchestrating a complex transcriptional network. The activation of IFN-α signaling pathway in endothelial cells re
Externí odkaz:
https://doaj.org/article/0e760e3a921c49da8c90407d15d0df2a
Autor:
Ravelli, Cosetta (AUTHOR), Corsini, Michela (AUTHOR), Ventura, Anna (AUTHOR), Domenichini, Mattia (AUTHOR), Grillo, Elisabetta (AUTHOR), Mitola, Stefania (AUTHOR)
Publikováno v:
PLoS ONE. 7/29/2024, Vol. 19 Issue 7, p1-1. 1p.
Autor:
Silvia Codenotti, Daniela Zizioli, Luca Mignani, Sara Rezzola, Giovanna Tabellini, Silvia Parolini, Arianna Giacomini, Michela Asperti, Maura Poli, Delia Mandracchia, Marika Vezzoli, Simona Bernardi, Domenico Russo, Stefania Mitola, Eugenio Monti, Luca Triggiani, Davide Tomasini, Stefano Gastaldello, Matteo Cassandri, Rossella Rota, Francesco Marampon, Alessandro Fanzani
Publikováno v:
Cells, Vol 11, Iss 18, p 2859 (2022)
In pediatric rhabdomyosarcoma (RMS), elevated Akt signaling is associated with increased malignancy. Here, we report that expression of a constitutively active, myristoylated form of Akt1 (myrAkt1) in human RMS RD cells led to hyperactivation of the
Externí odkaz:
https://doaj.org/article/53f88aa7bd2f418f81b3c269dfdb9607