Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Stefania, Meini"'
Autor:
Rose-Marie Catalioto, Claudio Valenti, Francesca Bellucci, Cecilia Cialdai, Maria Altamura, Laura Digilio, Andrea Ugo Enrico Pellacani, Stefania Meini
Publikováno v:
Heliyon, Vol 7, Iss 6, Pp e07314- (2021)
Achieving durable protective immunity following vaccination is dependent on many factors, including vaccine composition and antigen dose, and it has been investigated for various types of vaccines. Aim of the present study was to investigate the over
Externí odkaz:
https://doaj.org/article/b3af71dcfd1d4680b139018984c7ebff
Autor:
Stefania Meini, Cecilia Cialdai, Maria Altamura, Francesca Bellucci, Claudio Valenti, Andrea Ugo Enrico Pellacani, Laura Digilio, Rose-Marie Catalioto
Publikováno v:
Heliyon, Vol 7, Iss 6, Pp e07314-(2021)
Heliyon
Heliyon
Achieving durable protective immunity following vaccination is dependent on many factors, including vaccine composition and antigen dose, and it has been investigated for various types of vaccines. Aim of the present study was to investigate the over
Autor:
Erika Terzuoli, Stefania Meini, Paola Cucchi, Claudio Catalani, Cecilia Cialdai, Carlo Alberto Maggi, Antonio Giachetti, Marina Ziche, Sandra Donnini
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84358 (2014)
Bradykinin (BK) induces angiogenesis by promoting vessel permeability, growth and remodeling. This study aimed to demonstrate that the B2R antagonist, fasitibant, inhibits the BK pro-angiogenic effects.We assesed the ability of fasibitant to antagoni
Externí odkaz:
https://doaj.org/article/db8eba0e43004b1c94d91555623eca59
Autor:
Manuela Tramontana, Attilio Crea, C.A. Maggi, Paolo Santicioli, Francesca Bellucci, V D'Aranno, R Bugianesi, Stefania Meini, Lionel Bueno
Publikováno v:
British Journal of Pharmacology. 173:1329-1338
BACKGROUND AND PURPOSE The tachykinin NK2 receptor antagonist ibodutant is under Phase III clinical investigation to treat female patients with irritable bowel syndrome. The aim of this study was to investigate the NK2 receptor-related gender specifi
Autor:
Stefania Meini, Luigia Auriemma, Ettore Novellino, Diego Brancaccio, Pietro Campiglia, Carlo Alberto Maggi, Alfonso Carotenuto, Antonio Limatola, Isabel Gomez-Monterrey, Roberta d'Emmanuele di Villa Bianca, Francesco Merlino, Paolo Santicioli, Paolo Grieco
Publikováno v:
Journal of Peptide Science. 19:293-300
Urotensin II (U-II) is a disulfide bridged peptide hormone identified as the ligand of a G-protein-coupled receptor. Human U-II (H-Glu-Thr-Pro-Asp-c[Cys-Phe-Trp-Lys-Tyr-Cys]-Val-OH) has been described as the most potent vasoconstrictor compound ident
Autor:
Ali Munaim Yousif, Luigia Auriemma, Paolo Grieco, Paolo Santicioli, Daniela Marasco, Carlo Alberto Maggi, Stefania Meini, Isabel Gomez-Monterrey, Alfonso Carotenuto, Pietro Campiglia, Francesco Merlino, Antonio Limatola, Ettore Novellino
Publikováno v:
Journal of medicinal chemistry. 57(14)
We have optimized 1 (P5U) and urantide, two important ligands at the h-UT receptor, designing several analogues by the exchange of the Tyr9 residue with different unnatural aromatic amino acids. This study allowed us to discover novel ligands with im
Autor:
Linda Piras, Paolo Grieco, Pietro Campiglia, Carlo Alberto Maggi, Stefania Meini, Ettore Novellino, Alfonso Carotenuto, Isabel Gomez-Monterrey, Diego Brancaccio, Francesco Merlino, Ali Munaim Yousif, Paolo Santicioli
Publikováno v:
ORCID
Microsoft Academic Graph
Microsoft Academic Graph
Previous modifications of the peptide sequence of human urotensin-II (U-II) led to the identification of two well-known ligands: P5U and urantide. These derivatives are considered to be the most representative agonist and antagonist, respectively, at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d180e2fb8b04528fb6e232daad3de3fc
http://hdl.handle.net/11588/635978
http://hdl.handle.net/11588/635978
Autor:
Mauro Galeazzi, Laura Tinti, Claudio Catalani, Antonella Fioravanti, Claudio Valenti, C.A. Maggi, Stefania Meini, Paola Cucchi, Francesca Bellucci, S. Niccolini
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 385:777-786
This study investigates the effect of the selective and potent B2 receptor antagonist fasitibant (MEN16132) on the proinflammatory effect of bradykinin (BK) and its interaction with interleukin 1β (IL-1β) in human synoviocytes. PGE2 content was det
Autor:
C.A. Maggi, Laura Quartara, Paola Cucchi, Luigi Rotondaro, Sandro Giuliani, Alessandro Giolitti, Francesca Bellucci, Sabrina Zappitelli, Claudio Catalani, Stefania Meini
Publikováno v:
British Journal of Pharmacology. 162:1202-1212
BACKGROUND AND PURPOSE Icatibant is a well-known kinin B2 receptor antagonist currently used for angiooedema attacks. MEN16132 is a non-peptide B2 receptor antagonist, more potent and long lasting than icatibant in different models. Here we studied t