Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Stefania, Carobbio"'
Autor:
Abdulbasit Amin, Marina Badenes, Johanna Tüshaus, Érika de Carvalho, Emma Burbridge, Pedro Faísca, Květa Trávníčková, André Barros, Stefania Carobbio, Pedro M. Domingos, Antonio Vidal-Puig, Luís F. Moita, Sarah Maguire, Kvido Stříšovský, Francisco J. Ortega, José Manuel Fernández-Real, Stefan F. Lichtenthaler, Colin Adrain
Publikováno v:
Molecular Metabolism, Vol 73, Iss , Pp 101731- (2023)
Objective: The metalloprotease ADAM17 (also called TACE) plays fundamental roles in homeostasis by shedding key signaling molecules from the cell surface. Although its importance for the immune system and epithelial tissues is well-documented, little
Externí odkaz:
https://doaj.org/article/05555155e4744951844c5a7be30e9720
Autor:
Vanessa Pellegrinelli, Elizabeth Figueroa-Juárez, Isabella Samuelson, Mueez U-Din, Sonia Rodriguez-Fdez, Samuel Virtue, Jennifer Leggat, Cankut Çubuk, Vivian J. Peirce, Tarja Niemi, Mark Campbell, Sergio Rodriguez-Cuenca, Joaquin Dopazo Blázquez, Stefania Carobbio, Kirsi A. Virtanen, Antonio Vidal-Puig
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112640- (2023)
Summary: The relevance of extracellular matrix (ECM) remodeling is reported in white adipose tissue (AT) and obesity-related dysfunctions, but little is known about the importance of ECM remodeling in brown AT (BAT) function. Here, we show that a tim
Externí odkaz:
https://doaj.org/article/abc6d1bed4df4ab1bb326033123fcdff
Autor:
Moisés Castellá, Albert Blasco-Roset, Marion Peyrou, Aleix Gavaldà-Navarro, Joan Villarroya, Tania Quesada-López, Leyre Lorente-Poch, Juan Sancho, Florian Szymczak, Anthony Piron, Sonia Rodríguez-Fernández, Stefania Carobbio, Albert Goday, Pere Domingo, Antonio Vidal-Puig, Marta Giralt, Décio L. Eizirik, Francesc Villarroya, Rubén Cereijo
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106847- (2023)
Summary: Adipose tissue from pheochromocytoma patients acquires brown fat features, making it a valuable model for studying the mechanisms that control thermogenic adipose plasticity in humans. Transcriptomic analyses revealed a massive downregulatio
Externí odkaz:
https://doaj.org/article/28b4ea636229492aaaac613396fa4a6a
Autor:
Marina Badenes, Abdulbasit Amin, Ismael González-García, Inês Félix, Emma Burbridge, Miguel Cavadas, Francisco José Ortega, Érika de Carvalho, Pedro Faísca, Stefania Carobbio, Elsa Seixas, Dora Pedroso, Ana Neves-Costa, Luís F. Moita, José Manuel Fernández-Real, António Vidal-Puig, Ana Domingos, Miguel López, Colin Adrain
Publikováno v:
Molecular Metabolism, Vol 31, Iss , Pp 67-84 (2020)
Objective: Obesity is the result of positive energy balance. It can be caused by excessive energy consumption but also by decreased energy dissipation, which occurs under several conditions including when the development or activation of brown adipos
Externí odkaz:
https://doaj.org/article/f8f41233350747b288ea15f1198e92df
Autor:
Vian Azzu, Michele Vacca, Ioannis Kamzolas, Zoe Hall, Jack Leslie, Stefania Carobbio, Samuel Virtue, Susan E. Davies, Agnes Lukasik, Martin Dale, Mohammad Bohlooly-Y, Animesh Acharjee, Daniel Lindén, Guillaume Bidault, Evangelia Petsalaki, Julian L. Griffin, Fiona Oakley, Michael E.D. Allison, Antonio Vidal-Puig
Publikováno v:
Molecular Metabolism, Vol 48, Iss , Pp 101210- (2021)
Objective: Non-alcoholic fatty liver disease (NAFLD) is a silent pandemic associated with obesity and the metabolic syndrome, and also increases cardiovascular- and cirrhosis-related morbidity and mortality. A complete understanding of adaptive compe
Externí odkaz:
https://doaj.org/article/e22a0520a7ea4213a3c9346e79e25390
Autor:
Alba Sabaté-Pérez, Montserrat Romero, Paula Sànchez-Fernàndez-de-Landa, Stefania Carobbio, Michail Mouratidis, David Sala, Pablo Engel, Paula Martínez-Cristóbal, Josep A Villena, Sam Virtue, Antonio Vidal-Puig, Manuel Palacín, Xavier Testar, Antonio Zorzano
Publikováno v:
Autophagy. 19:904-925
Brown adipose tissue (BAT) thermogenesis affects energy balance, and thereby it has the potential to induce weight loss and to prevent obesity. Here, we document a macroautophagic/autophagic-dependent mechanism of peroxisome proliferator-activated re
Autor:
Stefania Carobbio, Antonio Vidal-Puig
Publikováno v:
Encyclopedia of Cell Biology ISBN: 9780128216248
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ecfe9b88f71c70a18f175bb109715b6
https://doi.org/10.1016/b978-0-12-821618-7.00091-2
https://doi.org/10.1016/b978-0-12-821618-7.00091-2
Autor:
Stefania Carobbio, Antonio Vidal-Puig
Publikováno v:
Thermogenic Fat ISBN: 9781071631669
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8575512ce0c7523297213cd7a934017
https://doi.org/10.1007/978-1-0716-3167-6_1
https://doi.org/10.1007/978-1-0716-3167-6_1
Autor:
Joycelyn Tan, Sam Virtue, Dougall M. Norris, Olivia J. Conway, Ming Yang, Christopher Gribben, Fatima Lugtu, Ioannis Kamzolas, James R. Krycer, Richard J. Mills, Conceição Pereira, Martin Dale, Amber S. Shun-Shion, Harry J. M. Baird, James A. Horscroft, Alice P. Sowton, Marcella Ma, Stefania Carobbio, Evangelia Petsalaki, Andrew J. Murray, David C. Gershlick, James E. Hudson, Ludovic Vallier, Kelsey H Fisher-Wellman, Christian Frezza, Antonio Vidal-Puig, Daniel J. Fazakerley
SUMMARYCell culture is generally considered to be hyperoxic. However, the importance of cellular oxygen consumption is often underappreciated, with rates of oxygen consumption often sufficient to cause hypoxia at cell monolayers. We initially focused
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fe7ad781bc0666a5a17fe82ad499dc9
https://doi.org/10.1101/2022.11.29.516437
https://doi.org/10.1101/2022.11.29.516437
Autor:
Padraic G. Fallon, Betania Mahler-Araujo, Martin Dale, Anne-Claire Guénantin, Guillaume Bidault, Aurelien Dugourd, Marcella Ma, Arthur Kaser, Stefania Carobbio, Jennifer Leggat, Julio Saez-Rodriguez, Helen E. Jolin, Andrew N J McKenzie, Kasparas Petkevicius, Brian Y H Lam, Samuel Virtue, Antonio Vidal-Puig
Publikováno v:
Nature Metabolism. 3:1150-1162
Macrophages exhibit a spectrum of activation states ranging from classical to alternative activation1. Alternatively, activated macrophages are involved in diverse pathophysiological processes such as confining tissue parasites2, improving insulin se