Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Stefan Zavala"'
Autor:
Sajel Patel, Sally Ou, Christopher Carreras, Peter J. Licari, Timothy Leaf, Scott Frykman, Lawrence Cadapan, Elaine Woo, Gary W. Ashley, John R. Carney, Mark A. Burlingame, Stefan Zavala
Publikováno v:
Journal of Biotechnology. 92:217-228
A method was developed for the large-scale bioconversion of novel 6-deoxyerythronolide B (6-dEB) analogs into erythromycin analogs. Erythromycin biosynthesis in Saccharopolyspora erythraea proceeds via the formation of a polyketide aglycone, 6-dEB, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b8afea1ad008ceaa79b68c8059b8f16
https://doi.org/10.1016/s0168-1656(01)00372-8
https://doi.org/10.1016/s0168-1656(01)00372-8
Publikováno v:
Journal of Industrial Microbiology & Biotechnology. 28:12-16
FK520, also called ascomycin, is an immunosuppressive agent produced by Streptomyces hygroscopicus. Engineering the polyketide synthase genes of the parent strain generated novel FK520 analogs with the potential for improved in vivo stability. By rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfe6c987365612f4106bd0a9ba493849
https://doi.org/10.1038/sj.jim.7000208
https://doi.org/10.1038/sj.jim.7000208
Autor:
Stefan Zavala, Lawrence Cadapan, Courtney M. Starks, Peter J. Licari, John R. Carney, Elaine J. Woo, Robert L. Arslanian
Publikováno v:
ChemInform. 33
Streptomyces platensis (strain NRRL 18993), a producer of dorrigocins, was shown to produce migrastatin, a cyclic congener of dorrigocin A previously reported from a different organism. Additionally a new compound isomeric to migrastatin, isomigrasta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13167b7935102ddb63db759db2cefc7a
https://doi.org/10.1002/chin.200233243
https://doi.org/10.1002/chin.200233243
Autor:
Lawrence Cadapan, Peter J. Licari, Stefan Zavala, Courtney M. Starks, Elaine J. Woo, Robert L. Arslanian, John R. Carney
Publikováno v:
The Journal of antibiotics. 55(2)
Streptomyces platensis (strain NRRL 18993), a producer of dorrigocins, was shown to produce migrastatin, a cyclic congener of dorrigocin A previously reported from a different organism. Additionally a new compound isomeric to migrastatin, isomigrasta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fed7f938884f8a6e5dc48acce75be7f9
https://pubmed.ncbi.nlm.nih.gov/12002995
https://pubmed.ncbi.nlm.nih.gov/12002995
Autor:
Robert L. Arslanian, Peter J. Licari, Stefan Zavala, P.L.C. Small, John R. Carney, Lawrence Cadapan
Publikováno v:
FEMS microbiology letters. 205(2)
Mycolactones are polyketide toxins produced by Mycobacterium ulcerans, the causative agent of the tropical skin disease known as Buruli ulcer. Development of novel therapeutic agents from mycolactones has been hindered by the difficulty of producing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1612ca870dfad73533c0e4e163873d5e
https://pubmed.ncbi.nlm.nih.gov/11750832
https://pubmed.ncbi.nlm.nih.gov/11750832