Zobrazeno 1 - 10
of 585
pro vyhledávání: '"Stefan Werner"'
Autor:
Nishit Goradia, Stefan Werner, Edukondalu Mullapudi, Sarah Greimeier, Lina Bergmann, Andras Lang, Haydyn Mertens, Aleksandra Węglarz, Simon Sander, Grzegorz Chojnowski, Harriet Wikman, Oliver Ohlenschläger, Gunhild von Amsberg, Klaus Pantel, Matthias Wilmanns
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract While the elucidation of regulatory mechanisms of folded proteins is facilitated due to their amenability to high-resolution structural characterization, investigation of these mechanisms in disordered proteins is more challenging due to the
Externí odkaz:
https://doaj.org/article/5074a5174b144e20817298b0df93967f
Autor:
Svenja Schneegans, Jana Löptien, Angelika Mojzisch, Desirée Loreth, Oliver Kretz, Christoph Raschdorf, Annkathrin Hanssen, Antonia Gocke, Bente Siebels, Karthikeyan Gunasekaran, Yi Ding, Leticia Oliveira-Ferrer, Laura Brylka, Thorsten Schinke, Hartmut Schlüter, Ilkka Paatero, Hannah Voß, Stefan Werner, Klaus Pantel, Harriet Wikman
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-18 (2024)
Abstract Background Metastasis is the leading cause of cancer-related death in non-small cell lung cancer (NSCLC) patients. We previously showed that low HERC5 expression predicts early tumor dissemination and a dismal prognosis in NSCLC patients. He
Externí odkaz:
https://doaj.org/article/8ee82af4958b47ecbef81f24542bd06c
Publikováno v:
IEEE Open Journal of Signal Processing, Vol 5, Pp 213-228 (2024)
This paper investigates quantile regression in the presence of non-convex and non-smooth sparse penalties, such as the minimax concave penalty (MCP) and smoothly clipped absolute deviation (SCAD). The non-smooth and non-convex nature of these problem
Externí odkaz:
https://doaj.org/article/e3c9eda5f5d54cb5bc03b2470d113e67
Autor:
Tim Wendlandt, Claudia Koch, Beate Britz, Anke Liedek, Nora Schmidt, Stefan Werner, Yuri Gleba, Farnoosh Vahidpour, Melanie Welden, Arshak Poghossian, Michael J. Schöning, Fabian J. Eber, Holger Jeske, Christina Wege
Publikováno v:
Viruses, Vol 15, Iss 9, p 1951 (2023)
Immunosorbent turnip vein clearing virus (TVCV) particles displaying the IgG-binding domains D and E of Staphylococcus aureus protein A (PA) on every coat protein (CP) subunit (TVCVPA) were purified from plants via optimized and new protocols. The la
Externí odkaz:
https://doaj.org/article/f9616d9c413a4c79a65d2c1559c2215f
Aggressive variants of prostate cancer: underlying mechanisms of neuroendocrine transdifferentiation
Autor:
Lina Merkens, Verena Sailer, Davor Lessel, Ella Janzen, Sarah Greimeier, Jutta Kirfel, Sven Perner, Klaus Pantel, Stefan Werner, Gunhild von Amsberg
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-20 (2022)
Abstract Prostate cancer is a hormone-driven disease and its tumor cell growth highly relies on increased androgen receptor (AR) signaling. Therefore, targeted therapy directed against androgen synthesis or AR activation is broadly used and continual
Externí odkaz:
https://doaj.org/article/af616c4e41df4e3faad5f2ada80aa9e5
Autor:
Sophie Knipper, Sabine Riethdorf, Stefan Werner, Derya Tilki, Markus Graefen, Klaus Pantel, Tobias Maurer
Publikováno v:
European Urology Open Science, Vol 34, Iss , Pp 55-58 (2021)
Promising oncological results have been reported for salvage lymph node dissection (SLND) with prostate-specific membrane antigen–radioguided surgery (PSMA-RGS) in patients with prostate cancer (PCa) recurrence. We performed a proof-of-principle st
Externí odkaz:
https://doaj.org/article/fb8392c0e4e24c03a885b6f6c00a1c64
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Livedoid vasculopathy is a rare, chronic-recurrent occlusive disorder in the microcirculation of dermal vessels. The clinical appearance is characterized by Livedo racemosa, painful ulceration, located in the distal parts of the lower extremities, fo
Externí odkaz:
https://doaj.org/article/c7c3c5cbcc844fd9b6ac2fcf8a93825c
Autor:
Ioannis Karampinis, Kai Nowak, Julian Koett, Christian Mess, Laura Wagner, Timo Gaiser, Frank Thomas Mayer, Lukas Goertz, Stefan Werner Schneider, Alexander Thomas Bauer
Publikováno v:
Haematologica, Vol 108, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/f7551241cf71478fb9d3f8d201dcc92d
Autor:
Marie-Therese Haider, Hiroaki Saito, Jennifer Zarrer, Kevin Uzhunnumpuram, Sankari Nagarajan, Vijayalakshmi Kari, Michael Horn-Glander, Stefan Werner, Eric Hesse, Hanna Taipaleenmäki
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-16 (2020)
Abstract Background Osteoclast activation is a hallmark of breast cancer-induced bone disease while little is known about the role of osteoblasts in this process. Recently, we identified the homeodomain protein TG-interacting factor-1 (Tgif1) as a cr
Externí odkaz:
https://doaj.org/article/28643997978b46f4b5443bc1c142b650
Publikováno v:
Cell Stress, Vol 3, Iss 6, Pp 165-180 (2019)
Epithelial cell adhesion molecule (EpCAM) is a transmembrane glycoprotein primarily known to mediate homotypic cell contacts in epithelia tissues. Because EpCAM expression is limited to normal and malignant epithelia, it has been used as diagnostic m
Externí odkaz:
https://doaj.org/article/3dcfec3b1b5b4fdeb850c1693852523c