Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Stefan Titz"'
Publikováno v:
Neuropharmacology. 95:321-331
Hyperpolarizing synaptic inhibition through GABAA and glycine receptors depends on the presence of the neuronal cation-chloride-cotransporter protein, KCC2. Several transcriptional and post-transcriptional mechanisms have been shown to regulate KCC2
Autor:
Mirka Kokocinska, Jochen Kuhse, Stefan Titz, Claus Bruehl, Andreas Draguhn, Andrea Schlicksupp, Chrysovalandis Schwale, Stefanie Schumacher, Joachim Kirsch
Publikováno v:
Histochemistry and cell biology. 145(6)
Synaptic inhibition in the spinal cord is mediated mainly by strychnine-sensitive glycine (GlyRs) and by γ-aminobutyric acid type A receptors (GABAAR). During neuronal maturation, neonatal GlyRs containing α2 subunits are replaced by adult-type Gly
Publikováno v:
Lancet (London, England). 385
Background Epilepsy is characterised by disturbed neuronal activity in the brain rendering it more susceptible to seizures. An understanding of the molecular mechanisms by which the balance between excitability and inhibition in neuronal networks is
Publikováno v:
European Journal of Neuroscience. 23:454-464
The Cl(-)-extruding neuron-specific K(+)-Cl(-) cotransporter KCC2, which establishes hyperpolarizing inhibition, can transport NH(4) (+) instead of K(+). It is, however, not clear whether KCC2 provides the only pathway for neuronal NH(4) (+) uptake.
Hyperpolarizing Inhibition Develops without Trophic support by GABA in Cultured Rat Midbrain Neurons
Publikováno v:
The Journal of Physiology. 550:719-730
During a limited period of early neuronal development, GABA is depolarizing and elevates [Ca2+]i, which mediates the trophic action of GABA in neuronal maturation. We tested the attractive hypothesis that GABA itself promotes the developmental change
Publikováno v:
Neuroscience Letters
The weaver mutation causes cell loss in the center of the substantia nigra, pars compacta. We compared the depression of γ-aminobutyric acid (GABA) A synaptic currents by the GABA B agonist R-baclofen in pars compacta neurons of weaver mice which we
Autor:
Stefan Titz, Ulrich Misgeld
Publikováno v:
Synaptic Plasticity and Transsynaptic Signaling ISBN: 9780387240084
Mounting evidence suggests that regulation of the neuronal Cl− transport capacity contributes to the plasticity of Cl− dependent postsynaptic inhibition in the brain. Shifts of [Cl−]i in neurons allow synaptic tuning across a voltage domain tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90937860fa42276e3c629feff1078d0a
https://doi.org/10.1007/0-387-25443-9_7
https://doi.org/10.1007/0-387-25443-9_7
Publikováno v:
Journal of neurophysiology. 90(4)
Elevated levels of [Formula: see text] in the brain impair neuronal function. We studied the effects of [Formula: see text] on postsynaptic inhibition of cultured rat brain neurons using whole cell recording under nominally [Formula: see text] -free
Autor:
Bernhard U. Keller, Stefan Titz
Publikováno v:
Journal of neurophysiology. 78(1)
Titz, Stefan and Bernhard U. Keller. Rapidly deactivating AMPA receptors determine excitatory synaptic transmission to interneurons in the nucleus tractus solitarius from rat. J. Neurophysiol. 78: 82–91, 1997. Excitatory synaptic transmission was i
Publikováno v:
The European journal of neuroscience. 7(12)
The prion protein (PrP) plays a pivotal role in transmissible spongiform encephalopathies such as Creutzfeldt-Jakob disease in humans and scrapie and bovine spongiform encephalopathy in animals. Previous experiments have suggested that the normal cel