Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Stefan Tholen"'
Autor:
Sebastian Kistenmacher, Melanie Schwämmle, Gottfried Martin, Eva Ulrich, Stefan Tholen, Oliver Schilling, Andreas Gießl, Ursula Schlötzer-Schrehardt, Felicitas Bucher, Günther Schlunck, Irina Nazarenko, Thomas Reinhard, Naresh Polisetti
Publikováno v:
Cells, Vol 13, Iss 7, p 623 (2024)
Limbal epithelial progenitor cells (LEPC) rely on their niche environment for proper functionality and self-renewal. While extracellular vesicles (EV), specifically small EVs (sEV), have been proposed to support LEPC homeostasis, data on sEV derived
Externí odkaz:
https://doaj.org/article/cd3bcdc523f747d3bd412ebb516efc7d
Autor:
Subash C. Malik, Jia-Di Lin, Stephanie Ziegler-Waldkirch, Stefan Tholen, Sachin S. Deshpande, Marius Schwabenland, Oliver Schilling, Andreas Vlachos, Melanie Meyer-Luehmann, Christian Schachtrup
Publikováno v:
Cells, Vol 12, Iss 23, p 2757 (2023)
Nuclear pore complexes (NPCs) are highly dynamic macromolecular protein structures that facilitate molecular exchange across the nuclear envelope. Aberrant NPC functioning has been implicated in neurodegeneration. The translocated promoter region (Tp
Externí odkaz:
https://doaj.org/article/3e5461d4500d4580a304040de803716d
Early enforcement of cell identity by a functional component of the terminally differentiated state.
Autor:
Zahra Bahrami-Nejad, Zhi-Bo Zhang, Stefan Tholen, Sanjeev Sharma, Atefeh Rabiee, Michael L Zhao, Fredric B Kraemer, Mary N Teruel
Publikováno v:
PLoS Biology, Vol 20, Iss 12, p e3001900 (2022)
How progenitor cells can attain a distinct differentiated cell identity is a challenging problem given the fluctuating signaling environment in which cells exist and that critical transcription factors are often not unique to a differentiation proces
Externí odkaz:
https://doaj.org/article/5e8b430c32cf466e9f706c3fc859c631
Publikováno v:
STAR Protocols, Vol 3, Iss 3, Pp 101623- (2022)
Summary: The FoF1 ATP synthase (ATPase) is one of the most important protein complexes in energy metabolism. The isolation of functional ATPase complexes is fundamental to address questions about its assembly, regulation, and functions. This protocol
Externí odkaz:
https://doaj.org/article/4cfeddc82e3441a7bc4945b583f44ea5
Autor:
Khaled I. Alatibi, Stefan Tholen, Zeinab Wehbe, Judith Hagenbuchner, Daniela Karall, Michael J. Ausserlechner, Oliver Schilling, Sarah C. Grünert, Jerry Vockley, Sara Tucci
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10556 (2021)
Medium-chain fatty acids (mc-FAs) are currently applied in the treatment of long-chain fatty acid oxidation disorders (lc-FAOD) characterized by impaired β-oxidation. Here, we performed lipidomic and proteomic analysis in fibroblasts from patients w
Externí odkaz:
https://doaj.org/article/562b87a8ed954c32bbae0c74300f6766
Autor:
Jonas Stritzker, Maryam Barsch, Patricia Otto-Mora, Nisha Rana, Tanja Gainey-Schleicher, Darko Castven, Stefan Tholen, Andreas Blaumeiser, Melanie Börries, Oliver Schilling, JensU. Marquardt, Robert Thimme, Irina Nazarenko, Bertram Bengsch
Publikováno v:
39. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber.
Autor:
Zahra Bahrami-Nejad, Zhi-Bo Zhang, Stefan Tholen, Sanjeev Sharma, Atefeh Rabiee, Michael L. Zhao, Fredric B. Kraemer, Mary N. Teruel
How progenitor cells can attain a distinct differentiated cell identity is a challenging problem given the fluctuating signaling environment in which cells exist and that critical transcription factors are often not unique to a differentiation proces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f68bc03600d62f0785d1e4347c0590f
Autor:
Gaia Gentile, Teresa Poggio, Antonella Catalano, Minna Voutilainen, Marta Andrade-Martinez, Tobias Ma, Roman Sankowski, Lina Goncarenko, Stefan Tholen, Kyuho Han, David Morgens, Marco Prinz, Michael Luebbert, Peter Bronsert, Michael Bassik, Michael Cleary, Oliver Schilling, Merja Heinäniemi, Jesus Duque Afonso
Publikováno v:
Blood. 140:503-504
Autor:
Roberto Ferrarese, Annalisa Izzo, Geoffroy Andrieux, Simon Lagies, Johanna Paulina Bartmuss, Anie Priscilla Masilamani, Alix Wasilenko, Daniela Osti, Stefania Faletti, Rana Schulzki, Shuai Yuan, Eva Kling, Valentino Ribecco, Dieter Henrik Heiland, Stefan Tholen, Marco Prinz, Giuliana Pelicci, Bernd Kammerer, Melanie Boerries, Maria Stella Carro
Publikováno v:
Life science alliance. 6(1)
Enhanced fatty acid synthesis is a hallmark of tumors, including glioblastoma. SREBF1/2 regulate the expression of enzymes involved in fatty acid and cholesterol synthesis. Yet, little is known about the precise mechanism regulating SREBP gene expres
Autor:
Stefan Tholen, Roma Patel, Agnieszka Agas, Kyle M. Kovary, Atefeh Rabiee, Hayley T. Nicholls, Ewa Bielczyk-Maczyńska, Wenting Yang, Fredric B. Kraemer, Mary N. Teruel
Publikováno v:
Cell Rep
Disruption of circadian glucocorticoid oscillations in Cushing's disease and chronic stress results in obesity and adipocyte hypertrophy, which is believed to be a main source of the harmful effects of obesity. Here, we recapitulate stress due to jet