Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Stefan T. Kaehler"'
Publikováno v:
Pharmaceutical Medicine. 29:323-329
In Europe, a new guideline on good pharmacovigilance practices–Module II: Pharmacovigilance system master file (PSMF)—was issued, and initially came into effect on 2 July 2012, with revision on 12 April 2013. The guideline describes the PSMF, whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c102f2b1c3be1d6da324e88633ce21b8
https://doi.org/10.1007/s40290-015-0116-4
https://doi.org/10.1007/s40290-015-0116-4
Autor:
Oswald Wagner, Lili Kazemi-Shirazi, Christiane Thallinger, Stefan T. Kaehler, Robert Sauermann, Claudia Marsik, Christian Joukhadar, Birgit Heinisch
Publikováno v:
Pharmacology. 81:181-186
Objective: The present study aimed at testing the effect of S- and R-ibuprofen on thromboxane B2 (TXB2), collagen-epinephrine closure time (CEPI-CT) and collagen-adenosine 5′-diphosphate closure time (CADP-CT) in lipopolysaccharide (LPS)-stimulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41e4f0cfc54fbb95b649d36caf0bb14e
https://doi.org/10.1159/000111759
https://doi.org/10.1159/000111759
Autor:
Christian Brenneis, K. Engelhardt, Erich Schmutzhard, Raimund Helbok, Peter Lackner, Ronny Beer, Bettina Pfausler, Stefan T. Kaehler, Apostolos Georgopoulos, Gregor Broessner
Publikováno v:
Antimicrobial Agents and Chemotherapy. 51:379-382
The pharmacokinetic profile of linezolid in cerebrospinal fluid (CSF) in five neurointensive care patients with staphylococcal ventriculitis was studied. The mean area under concentration-time curve (± standard deviation) was 63 ± 18.9 mg · h/lite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a79ae99079599f400ad9d0a43cc5e338
https://doi.org/10.1128/aac.00515-06
https://doi.org/10.1128/aac.00515-06
Autor:
Stefan T. Kaehler, Michelle Di Vito-Smith, Richard Pilot, Nicolette Bester, Theresa McGarry, Robert Bwire, Michael Riffkin
Publikováno v:
Advances in Therapy
Introduction Educational brochures are an important tool for communicating risk to health-care professionals. It is important to evaluate the impact of any risk minimization tool to understand the effectiveness of the strategy. The objective of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b025aac3f167a16c4666fb25e096236a
https://pubmed.ncbi.nlm.nih.gov/26801772
https://pubmed.ncbi.nlm.nih.gov/26801772
Autor:
Stefan T. Kaehler, Markus Mueller, Christian Joukhadar, Ilka Steiner, Robert Sauermann, Helmut Scheidl
Publikováno v:
Pharmacology. 77:46-52
The present study was carried out to test bioequivalence between two different oral desmopressin formulations. Sixty healthy volunteers were enrolled in the study and were randomly assigned to receive the test (T) and reference (R) drug in a two-peri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a5377ab939c56b9c135df084bd132b2
https://doi.org/10.1159/000092625
https://doi.org/10.1159/000092625
Autor:
Peter Bauer, Stefan T. Kaehler, Christian J. Kollenz, Hans-Georg Eichler, Markus Müller, Barbara S. Schenk, Christian Joukhadar
Publikováno v:
European Journal of Clinical Pharmacology. 59:631-636
The present study was carried out to test bioequivalence between two different desmopressin nasal spray preparations. Due to the high variability of plasma pharmacokinetics of intranasally administered peptides like desmopressin, appropriate study de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a235a3aefcd8d7b1e7e9c7a4b33430e8
https://doi.org/10.1007/s00228-003-0682-3
https://doi.org/10.1007/s00228-003-0682-3
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 364:105-109
Serotonergic mechanisms within the locus coeruleus (LC) are thought to be important in various functions including the stress response. In this study we investigated a possible role of nitric oxide (NO) as an intermediary messenger in the regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cc4319edcaf93a3540d39709c2cdea5
https://doi.org/10.1007/s002100100428
https://doi.org/10.1007/s002100100428
Autor:
Martin E. Keck, Athineos Philippu, Tobias Welt, Florian Holsboer, Mario Engelmann, Nicola Toschi, Nicolas Singewald, Stefan T. Kaehler, Rainer Landgraf, Carsten T. Wotjak, Gregor K. Elbel, Karl Ebner, Inge Sillaber
Publikováno v:
European Journal of Neuroscience. 12:3713-3720
Using intracerebral microdialysis in urethane-anaesthetized adult male Wistar rats, we monitored the effects of acute repetitive transcranial magnetic stimulation (rTMS; 20 trains of 20 Hz, 2.5 s) on the intrahypothalamic release of arginine vasopres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3baf208bbd6739d36280b6690930f2df
https://doi.org/10.1046/j.1460-9568.2000.00243.x
https://doi.org/10.1046/j.1460-9568.2000.00243.x
Publikováno v:
Brain Research. 859:249-254
The aim of the present study was to investigate the importance of the serotonergic transmission in the locus coeruleus (LC) to conditioned fear. Rats were conditioned to fear by exposing them to noise signal (N), light signal (L) and electric foot sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c2c9bd54bc8c71c9004b5ad51a0bad9
https://doi.org/10.1016/s0006-8993(00)01967-3
https://doi.org/10.1016/s0006-8993(00)01967-3
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 361:193-199
We investigated the importance of endogenous amino acids in the locus coeruleus in inescapable electric shock and conditioned fear. In naive rats and in rats exposed to noise (N), light (L) and electric shock (S) or to N + L only, the locus coeruleus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::055f387fc6964fe2e372ac9d24461b4d
https://doi.org/10.1007/s002109900172
https://doi.org/10.1007/s002109900172