Zobrazeno 1 - 10
of 249
pro vyhledávání: '"Stefan T Arold"'
Publikováno v:
PLoS ONE, Vol 17, Iss 3, p e0260420 (2022)
Cell-free transcription and translation systems promise to accelerate and simplify the engineering of proteins, biological circuits and metabolic pathways. Their encapsulation on microfluidic platforms can generate millions of cell-free reactions in
Externí odkaz:
https://doaj.org/article/f1b5a2db14e94c50aa411f1fff38257e
Autor:
Xiaochuan Zhao, Umar F Shahul Hameed, Vladlena Kharchenko, Chenyi Liao, Franceline Huser, Jacob M Remington, Anand K Radhakrishnan, Mariusz Jaremko, Łukasz Jaremko, Stefan T Arold, Jianing Li
Publikováno v:
eLife, Vol 10 (2021)
The DNA-binding protein H-NS is a pleiotropic gene regulator in gram-negative bacteria. Through its capacity to sense temperature and other environmental factors, H-NS allows pathogens like Salmonella to adapt their gene expression to their presence
Externí odkaz:
https://doaj.org/article/3fd228bea29d480e96df7597f5c5d48b
Autor:
Lydia WT Cheung, Katarzyna W Walkiewicz, Tabot MD Besong, Huifang Guo, David H Hawke, Stefan T Arold, Gordon B Mills
Publikováno v:
eLife, Vol 4 (2015)
The canonical action of the p85α regulatory subunit of phosphatidylinositol 3-kinase (PI3K) is to associate with the p110α catalytic subunit to allow stimuli-dependent activation of the PI3K pathway. We elucidate a p110α-independent role of homodi
Externí odkaz:
https://doaj.org/article/85e15669fdcb4bb2a77815a19f88261f
Publikováno v:
Environment International, Vol 190, Iss , Pp 108886- (2024)
Phenolic benzotriazole UV stabilizers (BUV) are commonly used additives in synthetic polymeric products, which constantly leak into the environment. They are persistent and bioaccumulative, and have been detected not only in fish, birds, and sea mamm
Externí odkaz:
https://doaj.org/article/e05c451777de44e1b8309ed5c288061d
Autor:
Jun Wang, Georgy Chistov, Junrui Zhang, Brandon Huntington, Israa Salem, Anandsukeerthi Sandholu, Stefan T. Arold
Publikováno v:
Heliyon, Vol 10, Iss 14, Pp e34487- (2024)
Targeted protein degradation (TPD) allows cells to maintain a functional proteome and to rapidly adapt to changing conditions. Methods that repurpose TPD for the deactivation of specific proteins have demonstrated significant potential in therapeutic
Externí odkaz:
https://doaj.org/article/d4e4bb07a8a54110afad496c7310d683
Autor:
Keying Guo, Raik Grünberg, Yuxiang Ren, Tianrui Chang, Shofarul Wustoni, Ondrej Strnad, Anil Koklu, Escarlet Díaz‐Galicia, Jessica Parrado Agudelo, Victor Druet, Tania Cecilia Hidalgo Castillo, Maximilian Moser, David Ohayon, Adel Hama, Ashraf Dada, Iain McCulloch, Ivan Viola, Stefan T. Arold, Sahika Inal
Publikováno v:
Advanced Science, Vol 11, Iss 27, Pp n/a-n/a (2024)
Abstract Electronic immunosensors are indispensable tools for diagnostics, particularly in scenarios demanding immediate results. Conventionally, these sensors rely on the chemical immobilization of antibodies onto electrodes. However, globular prote
Externí odkaz:
https://doaj.org/article/35c5a27cf762472db409c2989cc5b573
Autor:
Uldaeliz Trujillo, Edwin Vázquez-Rosa, Delise Oyola-Robles, Loren J Stagg, David A Vassallo, Irving E Vega, Stefan T Arold, Abel Baerga-Ortiz
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57859 (2013)
The polyunsaturated fatty acid (PUFA) synthases from deep-sea bacteria invariably contain multiple acyl carrier protein (ACP) domains in tandem. This conserved tandem arrangement has been implicated in both amplification of fatty acid production (add
Externí odkaz:
https://doaj.org/article/171f96551fb74e62a7b7f08468536a0a
Autor:
Virginie Ropars, Gilles Despouy, Marc-Henri Stern, Serge Benichou, Christian Roumestand, Stefan T Arold
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6567 (2009)
The T cell leukaemia/lymphoma 1A (TCL1A) oncoprotein plays key roles in several B and T cell malignancies. Lacking enzymatic activity, TCL1A's transforming action was linked to its capacity to co-activate the protein kinase AKT via binding to its ple
Externí odkaz:
https://doaj.org/article/7d4b5717a52e4914b5b4b05fba8d09ec
Autor:
Hiba El Hajj, Maryse Lebrun, Stefan T Arold, Henri Vial, Gilles Labesse, Jean François Dubremetz
Publikováno v:
PLoS Pathogens, Vol 3, Iss 2, p e14 (2007)
Toxoplasma gondii is an obligate intracellular parasite for which the discharge of apical organelles named rhoptries is a key event in host cell invasion. Among rhoptry proteins, ROP2, which is the prototype of a large protein family, is translocated
Externí odkaz:
https://doaj.org/article/1a4ed836cb914525abf6a684683e8d55
Autor:
Gerardo Ramos-Mandujano, Raik Grünberg, Yingzi Zhang, Chongwei Bi, Francisco J. Guzmán-Vega, Muhammad Shuaib, Rodion V. Gorchakov, Jinna Xu, Muhammad Tehseen, Masateru Takahashi, Etsuko Takahashi, Ashraf Dada, Adeel Nazir Ahmad, Samir M. Hamdan, Arnab Pain, Stefan T. Arold, Mo Li
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract The COVID-19 pandemic, caused by SARS-CoV-2, has emphasized the necessity for scalable diagnostic workflows using locally produced reagents and basic laboratory equipment with minimal dependence on global supply chains. We introduce an open-
Externí odkaz:
https://doaj.org/article/ceb1638e9bc44168ac3d94e8e40c9773