Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Stefan Sonnenberger"'
Autor:
Bodo Dobner, Thomas Schmitt, Beena Rai, Stefan Sonnenberger, Rakesh Gupta, Stefan Lange, Reinhard H.H. Neubert, Thomas Hauß
Publikováno v:
Chemistry and Physics of Lipids. 214:58-68
For this study mixtures based on the ceramides [NS] (NS = non-hydroxy-sphingosine) and [AP] (AP = α-hydroxy-phytosphingosine) in a 2:1 and 1:2 ratio, together with cholesterol and lignoceric acid, were investigated. These mixtures are modelling the
Autor:
Reinhard H.H. Neubert, Stefan Lange, Stefan Sonnenberger, Bodo Dobner, Thomas Schmitt, Thomas Hauß
Publikováno v:
Langmuir. 34:1742-1749
Neutron diffraction was used as a tool to investigate the lamellar as well as molecular nanostructure of ceramide-[NP]/ceramide-[AP]/cholesterol/lignoceric acid model systems with a nativelike 2:1 ratio and a 1:2 ratio to study the influence of the c
Autor:
Adina Eichner, Thomas Hauß, Bodo Dobner, Reinhard H.H. Neubert, Annett Schroeter, Stefan Sonnenberger
Publikováno v:
Chemistry and Physics of Lipids. 204:15-24
The very heterogeneous group of ceramides is known to be mandatory for proper barrier functions of the outermost layer of mammalian skin, referred to as stratum corneum (SC). The synthesis of a specifically deuterated ceramide [AP]-C18 variant is des
Publikováno v:
Chromatographia. 79:1615-1624
Ceramides (CERs) are integral parts of the intercellular lipid lamellae of the stratum corneum (SC), which is responsible for the barrier function of the skin. Many skin diseases such as atopic dermatitis and psoriasis are associated with depletion o
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 59:531-542
The synthesis of 12 deuterated ceramides with either a deuteration at the last carbon atom of the amide bound fatty acid or a perdeuterated fatty acid chain is described. The ceramides were prepared starting from sphingosine or phytosphingosine and
Autor:
Charles W. Gray, Stefan Sonnenberger, Kara Sevi-Maxwell, Elfi Sommer, Bodo Dobner, Reinhard H.H. Neubert, Johannes Wohlrab, K. Natalie Barger
Publikováno v:
Skin Pharmacology and Physiology. 29:130-134
Ceramides (CERs) are integral parts of the intercellular lipid lamellae of the stratum corneum (SC), which is responsible for the barrier function of the skin. Many skin diseases such as atopic dermatitis and psoriasis are associated with the depleti
Autor:
Bodo Dobner, Reinhard H.H. Neubert, Bruno Demé, Stefan Lange, Thomas Schmitt, Andreas Langner, Stefan Sonnenberger
Publikováno v:
Biochimica et biophysica acta. Biomembranes. 1861(1)
This study used neutron diffraction to investigate a ceramide-[NP] C24/[AP] C24 /[EOS]-br C30/cholesterol/lignoceric acid (0.6: 0.3: 0.1: 0.7: 1) based stratum corneum modelling system. By adding specifically deuterated ceramides-[NP]-D3, [AP]-D3, an
Autor:
Bruno Demé, Andrej Kováčik, Thomas Schmitt, Stefan Lange, Thomas Hauß, Sören Stahlberg, Bodo Dobner, Adina Eichner, Reinhard H.H. Neubert, Stefan Sonnenberger, Daniel Huster
Publikováno v:
Langmuir : the ACS journal of surfaces and colloids. 33(36)
The stratum corneum (SC) is the outermost layer of the skin and is composed of a multilayered assembly of mostly ceramids (Cer), free fatty acids, cholesterol (Chol), and cholesterol sulfate (Chol-S). Because of the tight packing of these lipids, the
Autor:
Thomas Schmitt, Adina Eichner, Andreas Langner, Stefan Lange, Reinhard H.H. Neubert, Thomas Hauß, Bodo Dobner, Stefan Sonnenberger
Publikováno v:
Journal of labelled compoundsradiopharmaceuticals. 60(7)
The synthesis of specific deuterated derivatives of the long chained ceramides [EOS] and [EOP] is described. The structural differences with respect to the natural compounds are founded in the substitution of the 2 double bonds containing linoleic ac
Autor:
Sören Stahlberg, Stefan Sonnenberger, Adina Eichner, Thomas Hauß, Daniel Huster, Annett Schroeter, Kateřina Vávrová, Barbora Školová, Alexander Vogel, Bodo Dobner, Reinhard H.H. Neubert
Publikováno v:
Soft matter. 13(10)
The stratum corneum is the outermost layer of the skin and protects the organism against external influences as well as water loss. It consists of corneocytes embedded in a mixture of ceramides, fatty acids, and cholesterol in a molar ratio of roughl