Zobrazeno 1 - 10
of 185
pro vyhledávání: '"Stefan Seregard"'
Autor:
Christina Herrspiegel, Flavia Plastino, Emma Lardner, Stefan Seregard, Pete A. Williams, Helder André, Gustav Stålhammar
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-15 (2023)
Abstract Purpose To develop a prognostic test based on a single blood sample obtained at the time of uveal melanoma diagnosis. Methods 83 patients diagnosed with posterior uveal melanoma between 1996 and 2000 were included. Peripheral serum samples w
Externí odkaz:
https://doaj.org/article/dfb5ef89f6d14bec8ec1dc4e25f047dc
Publikováno v:
BMC Ophthalmology, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Purpose To report the time trends in basic patient characteristics and the number of specimens received at a national referral center for ophthalmic pathology. Methods Data on patient sex, age at surgical resection and geographical location
Externí odkaz:
https://doaj.org/article/3b20f65dd98742b49f1536105867e385
Autor:
Viktor Gill, Christina Herrspiegel, Shiva Sabazade, Maria Fili, Louise Bergman, Bertil Damato, Stefan Seregard, Gustav Stålhammar
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundIn contrast to most other cancers, uveal melanoma (UM) is characterized by an absence of major improvements in patient survival during the last several decades. In this study, we examine changes in incidence rates, patient age and tumor siz
Externí odkaz:
https://doaj.org/article/88cc5e1c2e6742538fb1fd648b007421
Publikováno v:
Cancer Medicine, Vol 8, Iss 6, Pp 2784-2792 (2019)
Abstract Background Survival in metastasized cutaneous melanoma (CM) has been improved with the advent of inhibitors of immune checkpoints CTLA4 and PD‐1. In contrast, the response rate for inhibition of these checkpoints in uveal melanoma (UM) is
Externí odkaz:
https://doaj.org/article/336085c85e65481da93a067b95fbc702
Autor:
Viktor T. Gill, Shiva Sabazade, Christina Herrspiegel, Kathryn G. Ewens, Adrianna Opalko, Nicole Dan, Tinna Christersdottir, Alexander Berg Rendahl, Carol L. Shields, Stefan Seregard, Arupa Ganguly, Gustav Stålhammar
Publikováno v:
Acta Ophthalmologica. 101:34-48
To revisit the independent importance of ciliary body involvement (CBI), monosomy 3 (M3), tumour size, histological and clinical factors in uveal melanoma (UM) and to devise a new prognostic classification based on a combination of the American Joint
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b673e77a8d1ad2b52defe1891715dc8c
https://doi.org/10.1111/aos.15210
https://doi.org/10.1111/aos.15210
Autor:
Christina Herrspiegel, Flavia Plastino, Emma Lardner, Stefan Seregard, Helder André, Gustav Stålhammar
PurposeTo develop a prognostic test based on serum samples obtained at diagnosis of uveal melanoma (UM).DesignRetrospective cohort study.SubjectsEighty-three patients diagnosed with primary melanoma in the choroid or ciliary body at St. Erik Eye Hosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ac77928629c143032becef91cf94132
https://doi.org/10.21203/rs.3.rs-1608381/v1
https://doi.org/10.21203/rs.3.rs-1608381/v1
Autor:
Dawei Song, Sonia Cismas, Caitrin Crudden, Eric Trocme, Claire Worrall, Naida Suleymanova, Tingting Lin, Huiyuan Zheng, Stefan Seregard, Ada Girnita, Leonard Girnita
Publikováno v:
Oncogene. 42:858-858
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21ba23aedb33c0ec8baf233dd95c6413
https://doi.org/10.1038/s41388-023-02607-8
https://doi.org/10.1038/s41388-023-02607-8
Autor:
Tingting Lin, Leonard Girnita, Dawei Song, Eric Trocme, H. Zheng, Stefan Seregard, Naida Suleymanova, Caitrin Crudden, Ada Girnita, C. Worrall, Sonia Cismas
Publikováno v:
Oncogene. Nature Publishing Group
Oncogene, 41(4), 600-611. Nature Publishing Group
Song, D, Cismas, S, Crudden, C, Trocme, E, Worrall, C, Suleymanova, N, Lin, T, Zheng, H, Seregard, S, Girnita, A & Girnita, L 2022, ' IGF-1R is a molecular determinant for response to p53 reactivation therapy in conjunctival melanoma ', Oncogene, vol. 41, no. 4, pp. 600-611 . https://doi.org/10.1038/s41388-021-02111-x
Song, D, Cismas, S, Crudden, C, Trocme, E, Worrall, C, Suleymanova, N, Lin, T, Zheng, H, Seregard, S, Girnita, A & Girnita, L 2021, ' IGF-1R is a molecular determinant for response to p53 reactivation therapy in conjunctival melanoma ', Oncogene . https://doi.org/10.1038/s41388-021-02111-x
Oncogene, 41(4), 600-611. Nature Publishing Group
Song, D, Cismas, S, Crudden, C, Trocme, E, Worrall, C, Suleymanova, N, Lin, T, Zheng, H, Seregard, S, Girnita, A & Girnita, L 2022, ' IGF-1R is a molecular determinant for response to p53 reactivation therapy in conjunctival melanoma ', Oncogene, vol. 41, no. 4, pp. 600-611 . https://doi.org/10.1038/s41388-021-02111-x
Song, D, Cismas, S, Crudden, C, Trocme, E, Worrall, C, Suleymanova, N, Lin, T, Zheng, H, Seregard, S, Girnita, A & Girnita, L 2021, ' IGF-1R is a molecular determinant for response to p53 reactivation therapy in conjunctival melanoma ', Oncogene . https://doi.org/10.1038/s41388-021-02111-x
As the p53 tumor suppressor is rarely mutated in conjunctival melanoma (CM), we investigated its activation as a potential therapeutic strategy. Preventing p53/Mdm2 interaction by Nutlin-3, the prototypical Mdm2 antagonist, or via direct siRNA Mdm2 d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3803babfe5dd12b648655ab9c29a7ef9
https://research.vumc.nl/en/publications/402de235-aa61-47e7-b2ef-02e0d662b9ee
https://research.vumc.nl/en/publications/402de235-aa61-47e7-b2ef-02e0d662b9ee
Autor:
Leonard Girnita, Thonnie Rose O. See, Gustav Stålhammar, Eric Trocme, Katarina Bartuma, Maria Fili, Charlotta All-Eriksson, Helder André, Louise Bergman, Stefan Seregard
Publikováno v:
British Journal of Ophthalmology. 104:26-32
BackgroundEpiscleral brachytherapy is the most common eye-preserving treatment for medium-sized choroidal melanomas. γ-emitting iodine-125 (125I) and β-emitting ruthenium-106 (106Ru) are widely used. The latter is however generally reserved for thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82e6e1a13a433025d0bbfc634ccfcf63
https://doi.org/10.1136/bjophthalmol-2018-313419
https://doi.org/10.1136/bjophthalmol-2018-313419
Autor:
Tero Kivelä, Brenda L. Gallie, Matthew W. Wilson, Martine J. Jager, J.M. Caminal, Anibal Martin Folgar, Gregorius P M Luyten, Stefan Seregard, Gaurav Garg, Paul T. Finger, Cristina Gutiérrez, Vladimir Valskiy, Shigenobu Suzuki, Kimberly J. Chin, Mehmet Dogrusöz, Anush Amiryan, Barrett G. Haik, E. Rand Simpson, Maria Fili, Jaume Català-Mora, Ekaterina Semenova, S.V. Saakyan, David E. Pelayes, Arun D. Singh
Publikováno v:
British Journal of Ophthalmology, 106(4). BMJ PUBLISHING GROUP
ObjectiveTo analyse ocular and systemic findings of patients presenting with systemic metastasis.Methods and analysisIt is an international, multicentre, internet-enabled, registry-based retrospective data analysis. Patients were diagnosed between 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65131d1b74ee1409a99b8ecc860d8de0
https://bjo.bmj.com/content/bjophthalmol/early/2021/01/24/bjophthalmol-2020-317949.full.pdf
https://bjo.bmj.com/content/bjophthalmol/early/2021/01/24/bjophthalmol-2020-317949.full.pdf