Frequency and impact on renal transplant outcomes of urinary tract infections due to extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella species

Autor: Jakob E. Brune, Michael Dickenmann, Daniel Sidler, Laura N. Walti, Déla Golshayan, Oriol Manuel, Fadi Haidar, Dionysios Neofytos, Aurelia Schnyder, Katia Boggian, Thomas F. Mueller, Thomas Schachtner, Nina Khanna, Stefan Schaub, Caroline Wehmeier, the Swiss Transplant Cohort Study, Patrizia Amico, John-David Aubert, Adrian Bachofner, Vanessa Banz, Sonja Beckmann, Guido Beldi, Christoph Berger, Ekaterine Berishvili, Annalisa Berzigotti, Pierre-Yves Bochud, Sanda Branca, Heiner Bucher, Anne Cairoli, Emmanuelle Catana, Yves Chalandon, Sabina De Geest, Sophie De Seigneux, Joëlle Lynn Dreifuss, Michel Duchosal, Thomas Fehr, Sylvie Ferrari-Lacraz, Jaromil Frossard, Christian Garzoni, Nicolas Goossens, Jörg Halter, Dominik Heim, Christoph Hess, Sven Hillinger, Hans Hirsch, Patricia Hirt, Linard Hoessly, Günther Hofbauer, Uyen Huynh-Do, Franz Immer, Michael Koller, Andreas Kremer, Christian Kuhn, Bettina Laesser, Frédéric Lamoth, Roger Lehmann, Alexander Leichtle, Hans-Peter Marti, Michele Martinelli, Valérie McLin, Katell Mellac, Aurélia Merçay, Karin Mettler, Nicolas Müller, Ulrike Müller-Arndt, Beat Müllhaupt, Mirjam Nägeli, Graziano Oldani, Manuel Pascual, Jakob Passweg, Rosemarie Pazeller, Klara Posfay-Barbe, David Reineke, Juliane Rick, Anne Rosselet, Simona Rossi, Rössler, Silvia Rothlin, Frank Ruschitzka, Alexandra Scherrer, Dominik Schneidawind, Macé Schuurmans, Simon Schwab, Thierry Sengstag, Federico Simonetta, Jürg Steiger, Guido Stirniman, Ueli Stürzinger, Christian Van Delden, Jean-Pierre Venetz, Jean Villard, Julien Vionnet, Madeleine Wick, Markus Wilhlem, Patrick Yerly

Publikováno v: Frontiers in Medicine, Vol 11 (2024)

BackgroundEnterobacterales are often responsible for urinary tract infection (UTI) in kidney transplant recipients. Among these, Escherichia coli or Klebsiella species producing extended-spectrum beta-lactamase (ESBL) are emerging. However, there are

Externí odkaz: https://doaj.org/article/8a2807b2ba0b4fa9a10786acd1fc2ce2

Clinical prediction model for prognosis in kidney transplant recipients (KIDMO): study protocol

Autor: Simon Schwab, Daniel Sidler, Fadi Haidar, Christian Kuhn, Stefan Schaub, Michael Koller, Katell Mellac, Ueli Stürzinger, Bruno Tischhauser, Isabelle Binet, Déla Golshayan, Thomas Müller, Andreas Elmer, Nicola Franscini, Nathalie Krügel, Thomas Fehr, Franz Immer, the Swisstransplant Kidney Working Group (STAN), the Swiss Transplant Cohort Study

Publikováno v: Diagnostic and Prognostic Research, Vol 7, Iss 1, Pp 1-9 (2023)

Abstract Background Many potential prognostic factors for predicting kidney transplantation outcomes have been identified. However, in Switzerland, no widely accepted prognostic model or risk score for transplantation outcomes is being routinely used

Externí odkaz: https://doaj.org/article/42f3e3141afc40f5996ec1dea1143359

Excellent Clinical Long-Term Outcomes of Kidney Transplantation From Small Pediatric Donors (Age ≤ 5 Years) Despite Early Hyperfiltration Injury

Autor: Felix Burkhalter, Yvonne Holzmann, Argyrios Georgalis, Caroline Wehmeier, Patricia Hirt-Minkowski, Gideon Hoenger, Helmut Hopfer, Lorenz Guerke, Juerg Steiger, Stefan Schaub, Patrizia Amico

Publikováno v: Canadian Journal of Kidney Health and Disease, Vol 10 (2023)

Background: The use of small pediatric donors (age ≤ 5 years and body weight < 20kg) for adult transplant recipients is still regarded controversially in terms of early complications, long-term outcomes, and development of hyperfiltration injury du

Externí odkaz: https://doaj.org/article/b29e347f6b994f94a3203f5915c79d28

Snowflake epitope matching correlates with child-specific antibodies during pregnancy and donor-specific antibodies after kidney transplantation

Autor: Matthias Niemann, Yara Strehler, Nils Lachmann, Fabian Halleck, Klemens Budde, Gideon Hönger, Stefan Schaub, Benedict M. Matern, Eric Spierings

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

Development of donor-specific human leukocyte antigen (HLA) antibodies (DSA) remains a major risk factor for graft loss following organ transplantation, where DSA are directed towards patches on the three-dimensional structure of the respective organ

Externí odkaz: https://doaj.org/article/bbd636c2afcf480f920489f8af6db569

Peptides Derived From Mismatched Paternal Human Leukocyte Antigen Predicted to Be Presented by HLA-DRB1, -DRB3/4/5, -DQ, and -DP Induce Child-Specific Antibodies in Pregnant Women

Autor: Matthias Niemann, Benedict M. Matern, Eric Spierings, Stefan Schaub, Gideon Hönger

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

Predicted Indirectly ReCognizable Human Leukocyte Antigen (HLA) Epitopes (PIRCHE) are known to be a significant risk factor for the development of donor HLA-specific antibodies after organ transplantation. Most previous studies on PIRCHE limited thei

Externí odkaz: https://doaj.org/article/07b37444db6548e083a9b6a64c939cb0