Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Stefan Santen"'
Publikováno v:
British Journal of Surgery. 98:124-131
Background Radiotherapy is important in the management of pelvic malignancies, but radiation-induced intestinal damage is a dose-limiting factor. Microvascular injury and epithelial barrier dysfunction are considered to be rate-limiting aspects in ra
Publikováno v:
International Journal of Colorectal Disease. 23:527-534
Recruitment of leukocytes in the tissue microvasculature is considered to be a rate-limiting step in ischemia-reperfusion (I/R)-induced inflammation. The objective of this study was to examine the role of mast cells in CXC-chemokine- and I/R-provoked
Autor:
Yusheng Wang, Stefan Santen, Bengt Jeppsson, René Schramm, Henrik Thorlacius, Michael D. Menger
Publikováno v:
Inflammation Research. 56:452-458
Leukocyte recruitment is a key feature in ischemia-reperfusion (I/R) -provoked tissue injury. This study evaluated the role of P-selectin-glycoprotein ligand-1 (PSGL-1) in CXC chemokine- and ischemia-reperfusion- induced leukocyte rolling and adhesio
Autor:
Mattias Lepsenyi, Henrik Thorlacius, Artur Nemeth, Ingvar Syk, Jörgen Nielsen, Stefan Santen, Ervin Toth
Publikováno v:
BMC Research Notes; 4, no 274 (2011)
BMC Research Notes
BMC Research Notes, Vol 4, Iss 1, p 274 (2011)
BMC Research Notes
BMC Research Notes, Vol 4, Iss 1, p 274 (2011)
Background: Acute surgery in the management of malignant colonic obstruction is associated with high morbidity and mortality. The use of self-expanding metal stents (SEMS) is an alternative method of decompressing colonic obstruction. SEMS may allow
Publikováno v:
Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 61(4)
Heparin-binding protein (HBP) is a potent inducer of increased vascular permeability. The purpose of this study was to examine plasma levels of HBP in patients with shock.Fifty-three consecutive patients with septic and non-septic shock at a mixed-be
Autor:
Charlotte Thornberg, Andrada Mihaescu, Henrik Thorlacius, Stefan Santen, Bengt Jeppsson, Sören Mattsson
Publikováno v:
Surgery. 151(4)
Background Antiplatelet reagents have been reported to protect against intestinal damage associated with abdominal radiotherapy, but the mechanisms behind radiation-induced platelet-endothelium interactions are not known. We sought to define the adhe
Autor:
Stefan Santen, Bengt Jeppsson, Michael D. Menger, Matthias W. Laschke, Yusheng Wang, Henrik Thorlacius
Publikováno v:
International journal of colorectal disease. 25(9)
Leukocyte recruitment is a key feature in ischemia-reperfusion (I/R)-induced tissue injury. The aim of the present study was to investigate the effect of Rho-kinase inhibition on I/R-provoked leukocyte recruitment in the colon.C57BL/6 mice were subje
Publikováno v:
The British journal of surgery. 97(2)
BackgroundMicrovascular injury and epithelial barrier dysfunction are rate-limiting aspects in radiation enteropathy. This study examined the role of p38 mitogen-activated protein kinase (p38 MAPK) signalling in radiation-induced colitis in an experi
Autor:
Matthias W. Laschke, Yousheng Wang, Michael D. Menger, Henrik Thorlacius, Bengt Jeppsson, Andrada Mihaescu, Stefan Santen
Publikováno v:
Surgery. 145(3)
Background Our objective was to examine the role of p38 mitogen-activated protein kinase (MAPK) in ischemia-reperfusion (I/R)-induced recruitment or leukocytes in the colon. Methods C57/Bl6 mice were subjected to 30 minutes of ischemia by clamping th
Publikováno v:
Annals of surgery. 242(6)
Objective: To determine the role of p38 mitogen-activated protein kinase (MAPK) signaling in endotoxin-induced liver injury. Background: MAPKs have been reported to play a potential role in regulating inflammatory responses, but the role of p38 MAPK