Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Stefan R. Sweha"'
Autor:
Nneka E. Mbah, Amy L. Myers, Peter Sajjakulnukit, Chan Chung, Joyce K. Thompson, Hanna S. Hong, Heather Giza, Derek Dang, Zeribe C. Nwosu, Mengrou Shan, Stefan R. Sweha, Daniella D. Maydan, Brandon Chen, Li Zhang, Brian Magnuson, Zirui Zhu, Megan Radyk, Brooke Lavoie, Viveka Nand Yadav, Imhoi Koo, Andrew D. Patterson, Daniel R. Wahl, Luigi Franchi, Sameer Agnihotri, Carl J. Koschmann, Sriram Venneti, Costas A. Lyssiotis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract H3K27M diffuse midline gliomas (DMG), including diffuse intrinsic pontine gliomas (DIPG), exhibit cellular heterogeneity comprising less-differentiated oligodendrocyte precursors (OPC)-like stem cells and more differentiated astrocyte (AC)-l
Externí odkaz:
https://doaj.org/article/b60128e341cf4e8c9deb69669f6c0187
Autor:
Poonnada Jiraanont, Stefan R. Sweha, Reem R. AlOlaby, Marisol Silva, Hiu-Tung Tang, Blythe Durbin-Johnson, Andrea Schneider, Glenda M. Espinal, Paul J. Hagerman, Susan M. Rivera, David Hessl, Randi J. Hagerman, Nuanchan Chutabhakdikul, Flora Tassone
Publikováno v:
eNeurologicalSci, Vol 7, Iss C, Pp 49-56 (2017)
The prevalence of the fragile X premutation (55–200 CGG repeats) among the general population is relatively high, but there remains a lack of clear understanding of the links between molecular biomarkers and clinical outcomes. In this study we inve
Externí odkaz:
https://doaj.org/article/865a7e9b0d264cfb9a5483187697fad5
Autor:
Mateus Mota, Stefan R. Sweha, Matt Pun, Siva Kumar Natarajan, Yujie Ding, Chan Chung, Debra Hawes, Fusheng Yang, Alexander R. Judkins, Susanta Samajdar, Xuhong Cao, Lanbo Xiao, Abhijit Parolia, Arul M. Chinnaiyan, Sriram Venneti
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Diffuse midline gliomas (DMGs) including diffuse intrinsic pontine gliomas (DIPGs) bearing lysine-to-methionine mutations in histone H3 at lysine 27 (H3K27M) are lethal childhood brain cancers. These tumors harbor a global reduction in the transcript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48166f4bafdd480ae50c6dff209bbe18
https://doi.org/10.1073/pnas.2221175120
https://doi.org/10.1073/pnas.2221175120
Autor:
Nneka E. Mbah, Amy L. Myers, Chan Chung, Joyce K. Thompson, Hanna S. Hong, Peter Sajjakulnukit, Zeribe C. Nwosu, Mengrou Shan, Stefan R. Sweha, Daniella D. Maydan, Brandon Chen, Li Zhang, Brian Magnuson, Zirui Zui, Daniel R. Wahl, Luigi Franchi, Sameer Agnihotri, Carl J. Koschmann, Sriram Venneti, Costas A. Lyssiotis
H3K27M diffuse intrinsic pontine gliomas (DIPG) exhibit cellular heterogeneity comprising less-differentiated, stem-like glioma cells that resemble oligodendrocyte precursors (OPC) and more differentiated astrocyte (AC)-like cells. H3K27M DIPG stem-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e09f2bbf821cb523eaab86fc14098b1
https://doi.org/10.1101/2022.03.01.482555
https://doi.org/10.1101/2022.03.01.482555
Autor:
Dana Messinger, Micah K Harris, Jessica R Cummings, Chase Thomas, Tao Yang, Stefan R Sweha, Rinette Woo, Robert Siddaway, Martin Burkert, Stefanie Stallard, Tingting Qin, Brendan Mullan, Ruby Siada, Ramya Ravindran, Michael Niculcea, Abigail R Dowling, Joshua Bradin, Kevin F Ginn, Melissa A H Gener, Kathleen Dorris, Nicholas A Vitanza, Susanne V Schmidt, Jasper Spitzer, Jiang Li, Mariella G Filbin, Xuhong Cao, Maria G Castro, Pedro R Lowenstein, Rajen Mody, Arul Chinnaiyan, Pierre-Yves Desprez, Sean McAllister, Matthew D Dun, Cynthia Hawkins, Sebastian M Waszak, Sriram Venneti, Carl Koschmann, Viveka Nand Yadav
Publikováno v:
Neuro-oncology.
Background Diffuse midline gliomas (DMG) are highly invasive brain tumors with rare survival beyond two years past diagnosis and limited understanding of the mechanism behind tumor invasion. Previous reports demonstrate upregulation of the protein ID
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dabf6a54c13113f6039ef68b6ed1211a
https://pubmed.ncbi.nlm.nih.gov/35605606
https://pubmed.ncbi.nlm.nih.gov/35605606
Autor:
Hiu Tung Tang, Poonnada Jiraanont, Flora Tassone, David R Hessl, Glenda M. Espinal, Andrea Schneider, Stefan R. Sweha, Nuanchan Chutabhakdikul, Reem Rafik AlOlaby, Susan M. Rivera, Paul J. Hagerman, Marisol Silva, Blythe Durbin-Johnson, Randi J Hagerman
Publikováno v:
eNeurologicalSci, Vol 7, Iss C, Pp 49-56 (2017)
eNeurologicalSci
eNeurologicalSci
The prevalence of the fragile X premutation (55-200 CGG repeats) among the general population is relatively high, but there remains a lack of clear understanding of the links between molecular biomarkers and clinical outcomes. In this study we invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26e47cd01c6266608566eafab476c1c7
http://www.sciencedirect.com/science/article/pii/S2405650217300126
http://www.sciencedirect.com/science/article/pii/S2405650217300126
Autor:
Randi J Hagerman, Marisol Silva, Blythe Durbin-Johnson, Dalyir I. Pretto, Carolyn M. Yrigollen, Reem Rafik AlOlaby, Stefan R. Sweha, Flora Tassone
Publikováno v:
Brain & development, vol 39, iss 6
ObjectivesSeveral neurotransmitters involved in brain development are altered in fragile X syndrome (FXS), the most common monogenic cause of autism spectrum disorder (ASD). Serotonin plays a vital role in synaptogenesis and postnatal brain developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e86644b2a71c08fe49ca40e09b646d66
https://escholarship.org/uc/item/2fn4f906
https://escholarship.org/uc/item/2fn4f906
Autor:
Luis Manuel Murillo-Bonilla, Stefan R. Sweha, Lili Zhou, Carolyn M. Yrigollen, Roberta Polli, Alessandra Murgia, Elizabeth Berry-Kravis, Gabriel de Jesus Silva Arevalo, Isabel Fernandez-Carvajal, Flora Tassone, Blythe Durbin-Johnson, Patricia Cogram, Khaled M. A. Amiri, Sultana M.H. Faradz, Huda M. Shaheen
Publikováno v:
Intractable & rare diseases research, vol 3, iss 4
The CGG trinucleotide repeat within the FMR1 gene is associated with multiple clinical disorders, including fragile X-associated tremor/ataxia syndrome, fragile X-associated primary ovarian insufficiency, and fragile X syndrome. Differences in the di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::321f29c3f33bfc2f00ea0db79f07d3de
https://europepmc.org/articles/PMC4298645/
https://europepmc.org/articles/PMC4298645/