Zobrazeno 1 - 10
of 7 364
pro vyhledávání: '"Stefan O"'
Autor:
Sara Karimi-Farsijani, Kartikay Sharma, Marijana Ugrina, Lukas Kuhn, Peter Benedikt Pfeiffer, Christian Haupt, Sebastian Wiese, Ute Hegenbart, Stefan O. Schönland, Nadine Schwierz, Matthias Schmidt, Marcus Fändrich
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract Systemic ALys amyloidosis is a debilitating protein misfolding disease that arises from the formation of amyloid fibrils from C-type lysozyme. We here present a 2.8 Å cryo-electron microscopy structure of an amyloid fibril, which was isolat
Externí odkaz:
https://doaj.org/article/f810210754504cdca3221e85b66b7ea6
Autor:
Alice Marguerite Conrad, Julia Zimmermann, David Mohr, Matthias F. Froelich, Alexander Hertel, Nils Rathmann, Christoph Boesing, Manfred Thiel, Stefan O. Schoenberg, Joerg Krebs, Thomas Luecke, Patricia R. M. Rocco, Matthias Otto
Publikováno v:
Intensive Care Medicine Experimental, Vol 12, Iss 1, Pp 1-10 (2024)
Abstract Background Quantification of pulmonary edema in patients with acute respiratory distress syndrome (ARDS) by chest computed tomography (CT) scan has not been validated in routine diagnostics due to its complexity and time-consuming nature. Th
Externí odkaz:
https://doaj.org/article/f645d7f055ca4edebc38aeb565cada46
Autor:
Monique C. Minnema, Kazem Nasserinejad, Ute Hegenbart, Paula F. Ypma, Ka Lung Wu, Marie Jose Kersten, Sandra Croockewit, Sonja Zweegman, Lidwine Tick, Annemiek Broijl, Harry Koene, Gerard M. J. Bos, Pieter Sonneveld, Stefan O. Schönland
Publikováno v:
eJHaem, Vol 5, Iss 4, Pp 815-819 (2024)
Abstract The HOVON 104 studied bortezomib‐dexamethasone induction therapy and autologous stem cell transplantation in 50 patients, of whom 35 received an autologous stem cell transplantation (ASCT). We demonstrate a 5‐year overall survival (OS) o
Externí odkaz:
https://doaj.org/article/601abdedab4a41ad8368ea73a9b0936d
Autor:
Jannik Kahmann, Dominik Nörenberg, Theano Papavassiliu, Salman Ul Hassan Dar, Sandy Engelhardt, Stefan O. Schoenberg, Matthias F. Froelich, Isabelle Ayx
Publikováno v:
Insights into Imaging, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Objectives This study aims to investigate how radiomics analysis can help understand the association between plaque texture, epicardial adipose tissue (EAT), and cardiovascular risk. Working with a Photon-counting CT, which exhibits enhanced
Externí odkaz:
https://doaj.org/article/45e8513a209646ccbfb36bf1eb31905d
Autor:
Jannik Kahmann, Dominik Nörenberg, Theano Papavassiliu, Stefan O. Schoenberg, Matthias F. Froelich, Isabelle Ayx
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
AimRecent research highlights the role of pericoronary adipose tissue (PCAT) in coronary artery disease (CAD) development. PCAT has been recognized as a metabolically active tissue involved in local inflammation and oxidative stress, potentially impa
Externí odkaz:
https://doaj.org/article/00fc5ec256f74bd88106af81eb91863e
Autor:
Brandon J. Essink, Craig Shapiro, Marie Grace Dawn Isidro, Paul Bradley, Antoinette Pragalos, Mark Bloch, Joel Santiaguel, Melchor Victor Frias, Spiros Miyakis, Margarida Alves de Mesquita, Stefano Berrè, Charlotte Servais, Natasha Waugh, Claudia Hoffmann, Emna Baba, Oliver Schönborn-Kellenberger, Olaf-Oliver Wolz, Sven D. Koch, Tapiwa Ganyani, Philippe Boutet, Philipp Mann, Stefan O. Mueller, Roshan Ramanathan, Martin Robert Gaudinski, Nicolas Vanhoutte
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)
This phase 1, open-label, dose-escalation, multi-center study (NCT05477186) assessed the safety and immunogenicity of a booster dose of an mRNA COVID-19 vaccine (CV0501) encoding the SARS-CoV-2 Omicron BA.1 spike protein. Participants aged ≥ 18 yea
Externí odkaz:
https://doaj.org/article/b801d4c67eeb429f80a7051c7f35eae6
Publikováno v:
Hematology, Vol 29, Iss 1 (2024)
Outcomes of haploidentical hematopoietic stem cell transplantation (haplo-SCT) have improved over time. Graft failure and graft-versus-host disease (GVHD), which were important complications in major human leukocyte antigen (HLA)-disparity stem cell
Externí odkaz:
https://doaj.org/article/bd8518eacbb34ab190fea7107096a383
Autor:
Benjamin J. Lee, Jenny Liu, Shawn P. Griffin, Jean Doh, Stefan O. Ciurea, Piyanuch Kongtim, Elizabeth A. Brem
Publikováno v:
Cancer Medicine, Vol 13, Iss 19, Pp n/a-n/a (2024)
ABSTRACT Introduction Blastoid variant‐mantle cell lymphoma (BV‐MCL) represents an aggressive subset of patients with no established standard of care treatment approach. Methods We performed a retrospective analysis of the clinical characteristic
Externí odkaz:
https://doaj.org/article/f32d25f161b540169020aab4f31e69f2
Autor:
Alexander Hertel, Mustafa Kuru, Fabian Tollens, Hishan Tharmaseelan, Dominik Nörenberg, Nils Rathmann, Stefan O. Schoenberg, Matthias F. Froelich
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundThe liver is a frequent location of metastatic disease in various malignant tumor entities. Computed tomography (CT) is the most frequently employed modality for initial diagnosis. However, liver metastases may only be delineated vaguely on
Externí odkaz:
https://doaj.org/article/4423e3cbbdf640be9db60d8b45c1ed8c
Eculizumab for Shiga‐toxin‐induced hemolytic uremic syndrome in adults with neurological involvement
Autor:
Benjamin J. Lee, Zhaohui Arter, Jean Doh, Shawn P. Griffin, Pongthep Vittayawacharin, Steven Atallah, Kevin R. Shieh, Minh‐Ha Tran, Sonata Jodele, Piyanuch Kongtim, Stefan O. Ciurea
Publikováno v:
eJHaem, Vol 5, Iss 3, Pp 548-553 (2024)
Abstract The role of eculizumab in treating Shiga‐toxin‐producing Escherichia coli (STEC) hemolytic uremic syndrome (HUS) patients with neurological involvement remains unclear. We describe two distinctly different STEC‐HUS patients with neurol
Externí odkaz:
https://doaj.org/article/4bc406e7e8064859bcf876b3e1a7e21d