Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Stefan Mitterreiter"'
Autor:
Runa Hamid, Huy-Riem Ha, Edith Winkler, Harald Steiner, Richard M. Page, Christian Haass, Jessika A. Hopson, Frits Kamp, Ulrike Zeitschel, Tobias Stahl, Jochen Herms, Stefan F. Lichtenthaler, Steffen Rossner, Thomas U Mayer, Stefan Mitterreiter, Deborah J. Nelson
Publikováno v:
The journal of neuroscience 30(26), 8974-8983 (2010). doi:10.1523/JNEUROSCI.1199-10.2010
Journal of Neuroscience
Journal of Neuroscience
The two proteases beta-secretase and gamma-secretase generate the amyloid beta peptide and are drug targets for Alzheimer's disease. Here we tested the possibility of targeting the cellular environment of beta-secretase cleavage instead of the beta-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::699b243b2d6bb6a45dcac10bbbffc444
Autor:
Stefan Mitterreiter, Martina Malnar, Damir Omerbašić, Marko Kosicek, Silva Hećimović, Stefan F. Lichtenthaler, Alison Goate
Publikováno v:
Biochimica et biophysica acta / Molecular basis of disease 1802(7-8), 682-691 (2010). doi:10.1016/j.bbadis.2010.05.006
Biochimica et Biophysica Acta-Molecular Basis of Disease
Biochimica et Biophysica Acta-Molecular Basis of Disease, Elsevier, 2010, 1802 (7-8), pp.682. ⟨10.1016/j.bbadis.2010.05.006⟩
Biochimica et biophysica acta : molecular basis of diseas
Biochimica et Biophysica Acta-Molecular Basis of Disease
Biochimica et Biophysica Acta-Molecular Basis of Disease, Elsevier, 2010, 1802 (7-8), pp.682. ⟨10.1016/j.bbadis.2010.05.006⟩
Biochimica et biophysica acta : molecular basis of diseas
The link between cholesterol and Alzheimer's disease has recently been revealed in Niemann-Pick type C disease. We found that NPC1(-/-) cells show decreased expression of APP at the cell surface and increased processing of APP through the beta-secret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b2f6727d7dfbb240364d39e68b5ca47
Publikováno v:
Alzheimer's & Dementia. 4
Autor:
Stefan F. Lichtenthaler, Marcia L. Moss, Jörg W. Bartsch, Simone Reipschläger, Dirk Wildeboer, Silvia Naus, Ziqiang Guan, Stefan Mitterreiter
Publikováno v:
Biological chemistry. 387(3)
ADAM proteases are type I transmembrane proteins with extracellular metalloprotease domains. As for most ADAM family members, ADAM8 (CD156a, MS2) is involved in ectodomain shedding of membrane proteins and is linked to inflammation and neurodegenerat