Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Stefan Miemczyk"'
Autor:
Tomalika R. Ullah, Matt D. Johansen, Katherine R. Balka, Rebecca L. Ambrose, Linden J. Gearing, James Roest, Julian P. Vivian, Sunil Sapkota, W. Samantha N. Jayasekara, Daniel S. Wenholz, Vina R. Aldilla, Jun Zeng, Stefan Miemczyk, Duc H. Nguyen, Nicole G. Hansbro, Rajan Venkatraman, Jung Hee Kang, Ee Shan Pang, Belinda J. Thomas, Arwaf S. Alharbi, Refaya Rezwan, Meredith O’Keeffe, William A. Donald, Julia I. Ellyard, Wilson Wong, Naresh Kumar, Benjamin T. Kile, Carola G. Vinuesa, Graham E. Kelly, Olivier F. Laczka, Philip M. Hansbro, Dominic De Nardo, Michael P. Gantier
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract TANK-binding kinase 1 (TBK1) is a key signalling component in the production of type-I interferons, which have essential antiviral activities, including against SARS-CoV-2. TBK1, and its homologue IκB kinase-ε (IKKε), can also induce pro-
Externí odkaz:
https://doaj.org/article/780fdb67fa074e35823aa88357231e9d
Autor:
Bertil Wegmann, Patricia Tatemoto, Stefan Miemczyk, Johnny Ludvigsson, Carlos Guerrero-Bosagna
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Heavy metals are known to be able to cross the placental and blood brain barriers to affect critical neurodevelopmental processes in the fetus. We measured metal levels (Al, Cd, Hg, Li, Pb and Zn) in the cord blood of newborns and in the ser
Externí odkaz:
https://doaj.org/article/f09f97a1371a41e1a6aa16bda8812dc7
Autor:
Tristram A. J. Ryan, Alexander Hooftman, Aisling M. Rehill, Matt D. Johansen, Eóin C. O’ Brien, Juliana E. Toller-Kawahisa, Mieszko M. Wilk, Emily A. Day, Hauke J. Weiss, Pourya Sarvari, Emilio G. Vozza, Fabian Schramm, Christian G. Peace, Alessia Zotta, Stefan Miemczyk, Christina Nalkurthi, Nicole G. Hansbro, Gavin McManus, Laura O’Doherty, Siobhan Gargan, Aideen Long, Jean Dunne, Clíona Ní Cheallaigh, Niall Conlon, Michael Carty, Padraic G. Fallon, Kingston H. G. Mills, Emma M. Creagh, James S. O’ Donnell, Paul J. Hertzog, Philip M. Hansbro, Rachel M. McLoughlin, Małgorzata Wygrecka, Roger J. S. Preston, Zbigniew Zasłona, Luke A. J. O’Neill
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Excessive inflammation-associated coagulation is a feature of infectious diseases, occurring in such conditions as bacterial sepsis and COVID-19. It can lead to disseminated intravascular coagulation, one of the leading causes of mortality w
Externí odkaz:
https://doaj.org/article/0df3d79819534a4786cd65226889c413
Autor:
Anneliese S. Ashhurst, Matt D. Johansen, Joshua W. C. Maxwell, Skye Stockdale, Caroline L. Ashley, Anupriya Aggarwal, Rezwan Siddiquee, Stefan Miemczyk, Duc H. Nguyen, Joel P. Mackay, Claudio Counoupas, Scott N. Byrne, Stuart Turville, Megan Steain, James A. Triccas, Philip M. Hansbro, Richard J. Payne, Warwick J. Britton
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Current vaccines against SARS-CoV-2 reduce mortality but are less effective in preventing infection. Here the authors show that intranasal vaccination with a subunit vaccine including an TLR2-stimulating adjuvant induces strong neutralising antibody
Externí odkaz:
https://doaj.org/article/f49a73582fab4d0ca1138c1978b8a154
Autor:
Tristram A. J. Ryan, Alexander Hooftman, Aisling M. Rehill, Matt D. Johansen, Eóin C. O’ Brien, Juliana E. Toller-Kawahisa, Mieszko M. Wilk, Emily A. Day, Hauke J. Weiss, Pourya Sarvari, Emilio G. Vozza, Fabian Schramm, Christian G. Peace, Alessia Zotta, Stefan Miemczyk, Christina Nalkurthi, Nicole G. Hansbro, Gavin McManus, Laura O’Doherty, Siobhan Gargan, Aideen Long, Jean Dunne, Clíona Ní Cheallaigh, Niall Conlon, Michael Carty, Padraic G. Fallon, Kingston H. G. Mills, Emma M. Creagh, James S. O’ Donnell, Paul J. Hertzog, Philip M. Hansbro, Rachel M. McLoughlin, Małgorzata Wygrecka, Roger J. S. Preston, Zbigniew Zasłona, Luke A. J. O’Neill
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/3b72cd72017f45ae91810eb4f3826d16
Autor:
Shiva Rezaei, Julia Uffenorde, Oliver Gimm, Mohammad Ali Hosseinpour Feizi, Stefan Miemczyk, Luiz Lehmann Coutinho, Per Jensen, Carlos Guerrero-Bosagna, Fábio Pértille
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101202- (2022)
Summary: The GBS-MeDIP protocol combines two previously described techniques, Genotype-by-Sequencing (GBS) and Methylated-DNA-Immunoprecipitation (MeDIP). Our method allows for parallel and cost-efficient interrogation of genetic and methylomic varia
Externí odkaz:
https://doaj.org/article/0146adc3cc214f718188b6160c5437bf
Autor:
Haru Nomura, Melanie Wu, Jiangning Song, Andrew Hung, Shirley Tran, Hang TA, Fahima Akther, Yuao Wu, Matt Johansen, Keng Chew, Vinod Kumar, Trent Woodruff, Richard Clark, Johannes Koehbach, Bruno Lomonte, Carlos Rosado, Merlin Thomas, Marion Boudes, Cyril Reboul, Lachlan Rash, Linda Gallo, Sumia Essid, Dominika Elmlund, Stefan Miemczyk, Nicole Hansbro, Bernadette Saunders, Warwick Britton, Peter Sly, Ayaho Yamamoto, Julián Fernández, Peter Moyle, Kirsty Short, Philip Hansbro, Sanjaya Kuruppu, Ian Smith, Niwanthi Rajapakse
Angiotensin-converting enzyme 2 (ACE2) is protective in cardiovascular disease, lung injury and diabetes yet paradoxically underlies our susceptibility to SARs-CoV2 infection and the fatal heart and lung disease it can induce. Furthermore, diabetic p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0e805bf93ac1e9f1ccd3dfb8d9a2030
https://doi.org/10.21203/rs.3.rs-2642181/v1
https://doi.org/10.21203/rs.3.rs-2642181/v1
Autor:
Matt D. Johansen, Rashad M. Mahbub, Sobia Idrees, Duc H. Nguyen, Stefan Miemczyk, Prabuddha Pathinayake, Kristy Nichol, Nicole G. Hansbro, Linden J. Gearing, Paul J. Hertzog, David Gallego-Ortega, Warwick J. Britton, Bernadette M. Saunders, Peter A. Wark, Alen Faiz, Philip M. Hansbro
Publikováno v:
American journal of respiratory and critical care medicine, 206(6):712-729
Rationale: Patients with chronic obstructive pulmonary disease (COPD) develop more severe coronavirus disease (COVID-19); however, it is unclear whether they are more susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a69985829978ce01300b0210155227ec
https://pubmed.ncbi.nlm.nih.gov/35612929
https://pubmed.ncbi.nlm.nih.gov/35612929
Autor:
Michael Gantier, Tomalika Ullah, Matt Johansen, Katherine Balka, Rebecca Ambrose, Linden Gearing, Daniel Wenholz, Jun Zeng, Stefan Miemczyk, Duc Nguyen, Rajan Venkatraman, Matthew Dennis, Arwaf Alharbi, Julia Ellyard, Wilson Wong, Benjamin Kile, Carola Vinuesa, Graham Kelly, Philip Hansbro, Olivier Laczka, Dominic De Nardo, Nicole Hansbro, Naresh Kumar
TANK-binding kinase 1 (TBK1) is a key signalling component that drives the production of type-I interferons (IFNs), which have essential antiviral activities including against SARS-CoV-2. TBK1 and its homolog IκB kinase-ε (IKKε) can also induce th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64cd1d3344192278314d30f109e2d3d9
https://doi.org/10.21203/rs.3.rs-1336801/v1
https://doi.org/10.21203/rs.3.rs-1336801/v1
Autor:
Erica L. Stewart, Claudio Counoupas, Matt D. Johansen, Duc H. Nguyen, Stefan Miemczyk, Nicole G. Hansbro, Kia C. Ferrell, Anneliese Ashhurst, Sibel Alca, Caroline Ashley, Megan Steain, Warwick J. Britton, Philip M. Hansbro, Nikolai Petrovsky, James A. Triccas
Publikováno v:
Mucosal immunology. 15(6)
Multiple SARS-CoV-2 vaccine candidates have been approved for use and have had a major impact on the COVID-19 pandemic. There remains, however, a significant need for vaccines that are safe, easily transportable and protective against infection, as w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b66d49f99a10d592d1fbc4d75a5b4b9
https://pubmed.ncbi.nlm.nih.gov/36411332
https://pubmed.ncbi.nlm.nih.gov/36411332