Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Stefan Mereiter"'
Autor:
Christopher W Fell, Astrid Hagelkruys, Ana Cicvaric, Marion Horrer, Lucy Liu, Joshua Shing Shun Li, Johannes Stadlmann, Anton A Polyansky, Stefan Mereiter, Miguel Angel Tejada, Tomislav Kokotović, Venkat Swaroop Achuta, Angelica Scaramuzza, Kimberly A Twyman, Michelle M Morrow, Jane Juusola, Huifang Yan, Jingmin Wang, Margit Burmeister, Biswa Choudhury, Thomas Levin Andersen, Gerald Wirnsberger, Uffe Holmskov, Norbert Perrimon, Bojan Žagrović, Francisco J Monje, Jesper Bonnet Moeller, Josef M Penninger, Vanja Nagy
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 9, Pp n/a-n/a (2022)
Abstract Whole‐exome sequencing of two patients with idiopathic complex neurodevelopmental disorder (NDD) identified biallelic variants of unknown significance within FIBCD1, encoding an endocytic acetyl group‐binding transmembrane receptor with
Externí odkaz:
https://doaj.org/article/97ff532b47a541dcbc19af3c49df7a36
Autor:
Vanessa Monteil, Brett Eaton, Elena Postnikova, Michael Murphy, Benedict Braunsfeld, Ian Crozier, Franz Kricek, Janine Niederhöfer, Alice Schwarzböck, Helene Breid, Stephanie Devignot, Jonas Klingström, Charlotte Thålin, Max J Kellner, Wanda Christ, Sebastian Havervall, Stefan Mereiter, Sylvia Knapp, Anna Sanchez Jimenez, Agnes Bugajska‐Schretter, Alexander Dohnal, Christine Ruf, Romana Gugenberger, Astrid Hagelkruys, Nuria Montserrat, Ivona Kozieradzki, Omar Hasan Ali, Johannes Stadlmann, Michael R Holbrook, Connie Schmaljohn, Chris Oostenbrink, Robert H Shoemaker, Ali Mirazimi, Gerald Wirnsberger, Josef M Penninger
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 8, Pp n/a-n/a (2022)
Abstract The recent emergence of multiple SARS‐CoV‐2 variants has caused considerable concern due to both reduced vaccine efficacy and escape from neutralizing antibody therapeutics. It is, therefore, paramount to develop therapeutic strategies t
Externí odkaz:
https://doaj.org/article/8b99883b78934b478c6d1c13c62796ff
Autor:
João L. Pereira, Patrícia Cavaco, Ricardo C. da Silva, Ivette Pacheco-Leyva, Stefan Mereiter, Ricardo Pinto, Celso A. Reis, Nuno R. dos Santos
Publikováno v:
Translational Oncology, Vol 14, Iss 8, Pp 101125- (2021)
P-selectin glycoprotein ligand-1 (PSGL-1) is a membrane-bound glycoprotein expressed in lymphoid and myeloid cells. It is a ligand of P-, E- and L-selectin and is involved in T cell trafficking and homing to lymphoid tissues, among other functions. P
Externí odkaz:
https://doaj.org/article/559ea16ca1494372b7916069fc5a6b93
Autor:
Daniela Freitas, Diana Campos, Joana Gomes, Filipe Pinto, Joana A. Macedo, Rita Matos, Stefan Mereiter, Marta T. Pinto, António Polónia, Fátima Gartner, Ana Magalhães, Celso A. Reis
Publikováno v:
EBioMedicine, Vol 40, Iss , Pp 349-362 (2019)
Background: Changes in glycosylation are known to play critical roles during gastric carcinogenesis. Expression of truncated O-glycans, such as the Sialyl-Tn (STn) antigen, is a common feature shared by many cancers and is associated with cancer aggr
Externí odkaz:
https://doaj.org/article/164e60956d9443028d24a65dcfad0fe2
Autor:
Rita Matos, Kaori L. Fonseca, Stefan Mereiter, Ana Raquel Maceiras, Joana Gomes, Cristina Vilaplana, Fátima Gartner, Pedro N. S. Rodrigues, Celso A. Reis, Margarida Saraiva, Ana Magalhães
Publikováno v:
Microorganisms, Vol 9, Iss 1, p 99 (2021)
Glycans display increasingly recognized roles in pathological contexts, however, their impact in the host-pathogen interplay in many infectious diseases remains largely unknown. This is the case for tuberculosis (TB), one of the ten most fatal diseas
Externí odkaz:
https://doaj.org/article/6b47eb630e2d4adc878a51f2291856f6
Autor:
Beatriz Leão, Xiaogang Wen, Henrique O. Duarte, Irene Gullo, Gilza Gonçalves, Patrícia Pontes, Claudia Castelli, Francisca Diniz, Stefan Mereiter, Joana Gomes, Fátima Carneiro, Celso A. Reis
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3, p 1340 (2021)
Microsatellite instability (MSI) is a molecular phenotype due to a deficient DNA mismatch repair (dMMR). In colorectal cancer (CRC), dMMR/MSI is associated with several clinical and histopathological features, influences prognosis, and is a predictiv
Externí odkaz:
https://doaj.org/article/0ffab4d586e64647893eb8e781ae5efc
Autor:
Stefan Mereiter, Ana Magalhães, Barbara Adamczyk, Chunsheng Jin, Andreia Almeida, Lylia Drici, Maria Ibáñez-Vea, Martin R. Larsen, Daniel Kolarich, Niclas G. Karlsson, Celso A. Reis
Publikováno v:
Data in Brief, Vol 7, Iss , Pp 814-833 (2016)
Gastric carcinoma MKN45 cells stably transfected with the full-length ST3GAL4 gene were characterised by glycomic and sialoproteomic analysis. Complementary strategies were applied to assess the glycomic alterations induced by ST3GAL4 overexpression.
Externí odkaz:
https://doaj.org/article/8ed5740440894c80ae4e7c224feeafa4
Autor:
Meritxell Balmaña, Francisca Diniz, Tália Feijão, Cristina C. Barrias, Stefan Mereiter, Celso A. Reis
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 722 (2020)
In the scenario of personalized medicine, targeted therapies are currently the focus of cancer drug development. These drugs can block the growth and spread of tumor cells by interfering with key molecules involved in malignancy, such as receptor tyr
Externí odkaz:
https://doaj.org/article/acd3509ede834f248e5e1809f6c0cf48
Multicellular Human Gastric Cancer Spheroids Mimic the Glycosylation Phenotype of Gastric Carcinomas
Autor:
Meritxell Balmaña, Stefan Mereiter, Francisca Diniz, Tália Feijão, Cristina C. Barrias, Celso A. Reis
Publikováno v:
Molecules, Vol 23, Iss 11, p 2815 (2018)
Cellular glycosylation plays a pivotal role in several molecular mechanisms controlling cell–cell recognition, communication, and adhesion. Thus, aberrant glycosylation has a major impact on the acquisition of malignant features in the tumor progre
Externí odkaz:
https://doaj.org/article/6b588516691b49e9bf3817a652f59705
Autor:
Henrique O. Duarte, Meritxell Balmaña, Stefan Mereiter, Hugo Osório, Joana Gomes, Celso A. Reis
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 11, p 2262 (2017)
Aberrant expression and hyperactivation of the human epidermal growth factor receptor 2 (ErbB2) constitute crucial molecular events underpinning gastric neoplastic transformation. Despite ErbB2 extracellular domain being a well-known target for glyco
Externí odkaz:
https://doaj.org/article/158f0715b52d4071a77162832c13a9b7