Efficacy of epicutaneous Diractin® (ketoprofen in Transfersome® gel) for the treatment of pain related to eccentric muscle contractions

Autor: Matthias Rother, Egbert J Seidel, Priscilla M Clarkson, Stefan Mazgareanu, et al.

Publikováno v: Drug Design, Development and Therapy, Vol 2009, Iss default, Pp 143-149 (2009)

Matthias Rother1,2, Egbert J Seidel3, Priscilla M Clarkson4, Stefan Mazgareanu1, Ulrich Vierl1, ilka Rother21IDEA AG, Muenchen, Germany; 2X-pert Med GmbH, Graefelfing, Germany; 3Department Physical and Rehabilitation Medicine, Sophien- and Hufeland-C

Externí odkaz: https://doaj.org/article/c815fb088e07482a97709c9b2eceecd0

Ularitide as treatment of refractory ascites in cirrhosis- a study protocol for a randomised trial

Autor: Rasmus Gantzel, Markus Meyer, Stefan Mazgareanu, Niels Kristian Aagaard, Peter Jepsen, Johannes Holzmeister, Hugh Watson, Henning Grønbæk

Publikováno v: Gantzel, R H, Meyer, M, Mazgareanu, S, Aagaard, N K, Jepsen, P, Holzmeister, J, Watson, H & Grønbæk, H 2021, ' Ularitide as treatment of refractory ascites in cirrhosis-a study protocol for a randomised trial ', Danish Medical Journal, vol. 68, no. 12, A07210610 . < https://ugeskriftet.dk/dmj/ularitide-treatment-refractory-ascites-cirrhosis-study-protocol-randomised-trial >
Gantzel, R H, Meyer, M, Mazgareanu, S, Aagaard, N K, Jepsen, P, Holzmeister, J, Watson, H & Grønbæk, H 2021, ' Ularitide as treatment of refractory ascites in cirrhosis – a study protocol for a randomised trial ', Danish Medical Journal, vol. 68, no. 12, A07210610 .
Aarhus University
Gantzel, R H, Meyer, M, Mazgareanu, S, Aagaard, N K, Jepsen, P, Holzmeister, J, Watson, H & Grønbæk, H 2021, ' Ularitide as treatment of refractory ascites in cirrhosis-a study protocol for a randomised trial ', Danish Medical Journal, vol. 68, no. 11 .

INTRODUCTION Ascites is a frequent complication to cirrhosis. When ascites becomes refractory to standard diuretic pharmacotherapy, patients are facing a median survival of less than one year and most likely a need for frequent hospitalisations due t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1e5bbc4a9be0ae91b48b9eccb032ad63
https://pure.au.dk/portal/da/publications/ularitide-as-treatment-of-refractory-ascites-in-cirrhosis-a-study-protocol-for-a-randomised-trial(400aeb1f-2cd0-4322-a481-987507a125eb).html

Preclinical characterisation of NSAIDs in ultradeformable carriers or conventional topical gels

Autor: Stefan Mazgareanu, Gregor Cevc, Matthias Rother

Publikováno v: International Journal of Pharmaceutics. 360:29-39

We compared in vivo transport and biodistribution of ketoprofen applied on the skin in ultradeformable carriers (Diractin) or a conventional topical gel (Gabrilen) with oral drug (Oruvail); for reference we used in vitro study data. The drug from Gab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a957818b87930f2c8e08641d824ce5b
https://doi.org/10.1016/j.ijpharm.2008.01.051

Efficacy and safety of epicutaneous ketoprofen in Transfersome (IDEA-033) versus oral celecoxib and placebo in osteoarthritis of the knee: multicentre randomised controlled trial

Autor: Stefan Mazgareanu, Bernhard J Lavins, Werner Kneer, Matthias Rother, Klaus Lehnhardt, Egbert J Seidel

Publikováno v: Annals of the Rheumatic Diseases. 66:1178-1183

Objective: To compare epicutaneous ketoprofen in Transfersome (ultra-deformable vesicles, IDEA-033) versus oral celecoxib and placebo for relief of signs and symptoms in knee osteoarthritis. Methods: This was a multicentre, randomised, double-blind,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e96b10aea8fd18f31006795afe7d9c60
https://doi.org/10.1136/ard.2006.065128

Murine Leukemia Virus-Induced Neurodegeneration of Rats: Enhancement of Neuropathogenicity Correlates with Enhanced Viral Tropism for Macrophages, Microglia, and Brain Vascular Cells

Autor: S. Schwender, Stefan Mazgareanu, Andreas Hein, Monika Demuth, Stefanie Czub, Markus Czub, Rüdiger Dörries, Martina Rappold

Publikováno v: Virology. 214(1):239-244

A highly neuropathogenic retrovirus, NT40, was generated by serially passaging an infectious molecular clone of Friend murine leukemia virus, FB29, through F344 Fisher rats. NT40 induced severe neurological signs such as reflex abnormalities and atax

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e9831e410c0abb45c78978787ae4f0e