Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Stefan Masjosthusmann"'
Autor:
Battuja Dugershaw‐Kurzer, Jonas Bossart, Marija Buljan, Yvette Hannig, Sarah Zehnder, Govind Gupta, Vera M. Kissling, Patrycja Nowak‐Sliwinska, Judy R. vanBeijnum, Arjan W. Griffioen, Stefan Masjosthusmann, Etta Zühr, Ellen Fritsche, René Hornung, Thomas Rduch, Tina Buerki‐Thurnherr
Publikováno v:
Advanced Science, Vol 11, Iss 28, Pp n/a-n/a (2024)
Abstract Exposure to nanoparticles (NPs) in pregnancy is increasingly linked to adverse effects on embryo‐fetal development and health later in life. However, the developmental toxicity mechanisms of NPs are largely unknown, in particular potential
Externí odkaz:
https://doaj.org/article/2a31beb452ae480abf4e8493d6d513f5
Autor:
Laura Nimtz, Julia Hartmann, Julia Tigges, Stefan Masjosthusmann, Martin Schmuck, Eike Keßel, Stephan Theiss, Karl Köhrer, Patrick Petzsch, James Adjaye, Claudia Wigmann, Dagmar Wieczorek, Barbara Hildebrandt, Farina Bendt, Ulrike Hübenthal, Gabriele Brockerhoff, Ellen Fritsche
Publikováno v:
Stem Cell Research, Vol 45, Iss , Pp - (2020)
Neurotoxicity is mediated by a variety of modes-of-actions leading to disturbance of neuronal function. In order to screen larger numbers of compounds for their neurotoxic potential, in vitro functional neuronal networks (NN) might be helpful tools.
Externí odkaz:
https://doaj.org/article/6ce21a344da041f7ac23989029624edd
Autor:
Kristina Bartmann, Farina Bendt, Arif Dönmez, Daniel Haag, Eike Keßel, Stefan Masjosthusmann, Christopher Noel, Ji Wu, Peng Zhou, Ellen Fritsche
Proper brain development is based on the orchestration of key neurodevelopmental processes, including the formation and function of neural networks. If at least one key neurodevelopmental process is affected by a chemical, an adverse outcome is expec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f49dceb22460d83b6be4d23df085faba
https://doi.org/10.1101/2023.01.12.523741
https://doi.org/10.1101/2023.01.12.523741
Autor:
Jonathan Blum, Stefan Masjosthusmann, Kristina Bartmann, Farina Bendt, Xenia Dolde, Arif Dönmez, Nils Förster, Anna-Katharina Holzer, Ulrike Hübenthal, Hagen Eike Keßel, Sadiye Kilic, Jördis Klose, Melanie Pahl, Lynn-Christin Stürzl, Iris Mangas, Andrea Terron, Kevin M. Crofton, Martin Scholze, Axel Mosig, Marcel Leist, Ellen Fritsche
Developmental neurotoxicity (DNT) is a major safety concern for all chemicals of the human exposome. However, DNT data from animal studies are available for only a small percentage of manufactured compounds. Test methods with a higher throughput than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04065f0054d0235280408ccf7d7668ba
https://zenodo.org/record/7752644
https://zenodo.org/record/7752644
Autor:
Hagen Eike Keßel, Stefan Masjosthusmann, Kristina Bartmann, Jonathan Blum, Arif Dönmez, Nils Förster, Jördis Klose, Axel Mosig, Melanie Pahl, Marcel Leist, Martin Scholze, Ellen Fritsche
In the field of hazard assessment, Benchmark concentrations (BMC) and their associated uncertainty are of particular interest for regulatory decision making. The BMC estimation consists of various statistical decisions to be made, which depend largel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd6e108bfa48313822ffb51452e55d5b
https://doi.org/10.1101/2022.10.18.512648
https://doi.org/10.1101/2022.10.18.512648
Autor:
Adrian Covaci, Julia Tigges, Mamta Behl, Marcel Leist, Stefan Masjosthusmann, Hagen Eike Keßel, Lynn-Christin Stürzl, Ulrike Hübenthal, Andrea Rossi, Melanie Pahl, Jördis Klose, Nils Förster, Jonathan Blum, Katharina Koch, Sabine Schneider, Xenia Dolde, Ellen Fritsche, Farina Bendt, Anna-Katharina Holzer, Kristina Bartmann, Selina Woeste
Publikováno v:
Cell biology and toxicology
Due to their neurodevelopmental toxicity, flame retardants (FRs) like polybrominated diphenyl ethers are banned from the market and replaced by alternative FRs, like organophosphorus FRs, that have mostly unknown toxicological profiles. To study thei
Autor:
Stefan Masjosthusmann, Ellen Fritsche, Farina Bendt, Jenny Baumann, Clara Siebert, Ulrike Hübenthal
Publikováno v:
Chemosphere. 235:447-456
Arsenic exposure disturbs brain development in humans. Although developmental neurotoxicity (DNT) of arsenic has been studied in vivo and in vitro, its mode-of-action (MoA) is not completely understood. Here, we characterize the adverse neurodevelopm
Autor:
Nils Förster, Xiaohui Fan, Farina Bendt, Ellen Fritsche, Melanie Pahl, Joshua Butke, Hagen Eike Keßel, Axel Mosig, Ping-Chung Leung, Jördis Klose, Lu Li, Stefan Masjosthusmann
Publikováno v:
Cytometry. Part A : the journal of the International Society for Analytical CytologyREFERENCES. 101(5)
Neurosphere cultures consisting of primary human neural stem/progenitor cells (hNPC) are used for studying the effects of substances on early neurodevelopmental processes in vitro. Differentiating hNPCs migrate and differentiate into radial glia, neu
TBBPA targets converging key events of human oligodendrocyte development resulting in two novel AOPs
Autor:
Ellen Fritsche, Ulrike Hübenthal, Karl Köhrer, Patrick Petzsch, Farina Bendt, Katharina Schmuck, Katharina Koch, Stefan Masjosthusmann, Jördis Klose, Julia Tigges
Publikováno v:
ALTEX
Myelinating oligodendrocytes (OLs) establish saltatory nerve conduction during white matter development. Thus, interference with oligodendrogenesis leads to an adverse outcome on brain performance in the child due to aberrant myelination. An intertwi
Due to its high abundance and alarming toxic potential, arsenic is one of the most concerning environmental toxicants and still a global health concern. Consequences of chronic arsenic exposure for human health are diverse and range from skin lesions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24f694034c234ed24f2bb83294670c06
https://doi.org/10.1016/bs.ant.2020.12.002
https://doi.org/10.1016/bs.ant.2020.12.002