Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Stefan M. Szalay"'
Autor:
Peter Chiba, Kamran Gharehbaghi, Gabi Ressmann, Stefan M. Szalay, Christian Lhotka, Konrad Pillwein, Thomas Szekeres, Katharina Schuchter
Publikováno v:
Biochemical Pharmacology. 46:1903-1907
The activity of IMP dehydrogenase (EC 1.2.1.14), the key enzyme of de novo guanylate biosynthesis, was shown to be increased in tumor cells. Tiazofurin (TR), a potent and specific inhibitor of this enzyme, proved to be effective in the treatment of r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ec217efb3e882be225e607e29efc4fa
https://doi.org/10.1016/0006-2952(93)90630-f
https://doi.org/10.1016/0006-2952(93)90630-f
Autor:
Stefan M. Szalay, Katharina Schuchter, Thomas Szekeres, Hiremagalur N. Jayaram, Gabi Ressmann, Andreas Knoflach, Konrad Pillwein, Kamran Gharehbaghi, Peter Chiba, Benedikt Cermak
Publikováno v:
International Journal of Cancer. 55:92-95
The IMP dehydrogenase inhibitor, tiazofurin (TR)-2-β-D-ribofuranosylthiazole-4-carboxamide, which exhibited oncolytic activity in patients with chronic myelogenous leukaemia (CML) in blast crisis was found to inhibit the growth of human neuroblastom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b24eb1924440fc528444ff6b6435164
https://doi.org/10.1002/ijc.2910550117
https://doi.org/10.1002/ijc.2910550117