Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Stefan M Kanzok"'
Autor:
Rachel L Kooistra, Robin David, Ana C Ruiz, Sean W Powers, Kyle J Haselton, Kaitlyn Kiernan, Andrew M Blagborough, Ligin Solamen, Kenneth W Olsen, Catherine Putonti, Stefan M Kanzok
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0209699 (2018)
We recently identified three novel thioredoxin-like genes in the genome of the protozoan parasite Plasmodium that belong to the Phosducin-like family of proteins (PhLP). PhLPs are small cytosolic proteins hypothesized to function in G-protein signali
Externí odkaz:
https://doaj.org/article/21c6b8fb305b4f2f965d0ccb5256fea5
Autor:
Benjamin A Turturice, Michael A Lamm, James J Tasch, Angelika Zalewski, Rachel Kooistra, Eric H Schroeter, Sapna Sharma, Shin-Ichiro Kawazu, Stefan M Kanzok
Publikováno v:
PLoS Pathogens, Vol 9, Iss 1, p e1003136 (2013)
The Plasmodium ookinete develops over several hours in the bloodmeal of its mosquito vector where it is exposed to exogenous stresses, including cytotoxic reactive oxygen species (ROS). How the parasite adapts to these challenging conditions is not w
Externí odkaz:
https://doaj.org/article/88f55a54061740b0b9f45c4ac6e79eee
Autor:
Yash Gupta, Neha Sharma, Snigdha Singh, Jesus G. Romero, Vinoth Rajendran, Reagan M. Mogire, Mohammad Kashif, Jordan Beach, Walter Jeske, Poonam, Bernhards R. Ogutu, Stefan M. Kanzok, Hoseah M. Akala, Jennifer Legac, Philip J. Rosenthal, David J. Rademacher, Ravi Durvasula, Agam P. Singh, Brijesh Rathi, Prakasha Kempaiah
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1371 (2022)
Malaria elimination urgently needs novel antimalarial therapies that transcend resistance, toxicity, and high costs. Our multicentric international collaborative team focuses on developing multistage antimalarials that exhibit novel mechanisms of act
Externí odkaz:
https://doaj.org/article/51f533a3d8a647a8b2b71052ec3441fa
Autor:
Matthew C Weyenberg, Ravi Durvasula, Stefan M. Kanzok, Poonam, Catherine M. Pearce, Neha Sharma, Jesus G Romero, Raman Mathur, Steven Goicoechea, Brijesh Rathi, Prakasha Kempaiah, Yash Gupta, Hoseah M. Akala, Bharathi Daravath, Samuel K. Kwofie
Publikováno v:
Medicinal Research Reviews. 42:56-82
Calcium channels (CCs), a group of ubiquitously expressed membrane proteins, are involved in many pathophysiological processes of protozoan parasites. Our understanding of CCs in cell signaling, organelle function, cellular homeostasis, and cell cycl
Autor:
Brian B. Tarimo, Henry Chun Hin Law, Dingyin Tao, Rebecca Pastrana-Mena, Stefan M. Kanzok, Joram J. Buza, Rhoel R. Dinglasan
Publikováno v:
Proteomes, Vol 6, Iss 4, p 47 (2018)
Paraquat is a potent superoxide (O2−)-inducing agent that is capable of inducing an oxidative imbalance in the mosquito midgut. This oxidative imbalance can super-stress the malaria parasite, leading to arrested development in the mosquito midgut a
Externí odkaz:
https://doaj.org/article/78e2821877884ec6a0a17a468082073e
Autor:
Yash Gupta, Neha Sharma, Snigdha Singh, Jesus G. Romero, Vinoth Rajendran, Reagan M. Mogire, Raman Mathur, Mohammad Kashif, Jordan Beach, Walter Jeske, Poonam, Bernhards Ogutu, Stefan M. Kanzok, Hoseah M. Akala, Jennifer Legac, Philip J. Rosenthal, David J. Rademacher, Ravi Durvasula, Agam P. Singh, Brijesh Rathi, Prakasha Kempaiah
Publikováno v:
SSRN Electronic Journal.
Autor:
Stefan M. Kanzok, Brian B. Tarimo, Rhoel R. Dinglasan, Joram Buza, Dingyin Tao, Henry Chun Hin Law, Rebecca Pastrana-Mena, Bernadette Hritzo
Publikováno v:
BMC Research Notes, Vol 12, Iss 1, Pp 1-8 (2019)
BMC Research Notes
BMC Research Notes
Objective A fundamental understanding of redox homeostasis in Anopheles gambiae midgut cells under different oxidative conditions is missing. Such knowledge can aid in the development of new malaria transmission-blocking strategies aimed at disruptin
Autor:
Kyle J. Haselton, Sean W. Powers, Ana C. Ruiz, Catherine Putonti, Rachel L. Kooistra, Stefan M. Kanzok, Robin David, Ligin Solamen, Kaitlyn Kiernan, Kenneth W. Olsen, Andrew M. Blagborough
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0209699 (2018)
PLoS ONE
PLoS ONE
We recently identified three novel thioredoxin-like genes in the genome of the protozoan parasite Plasmodium that belong to the Phosducin-like family of proteins (PhLP). PhLPs are small cytosolic proteins hypothesized to function in G-protein signali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78294a78e050f2120d26649e8768b62b
http://hdl.handle.net/10044/1/76725
http://hdl.handle.net/10044/1/76725
Autor:
Joram J. Buza, Rebecca Pastrana-Mena, Dingyin Tao, Stefan M. Kanzok, Brian B. Tarimo, Rhoel R. Dinglasan, Henry Chun Hin Law
Publikováno v:
Proteomes, Vol 6, Iss 4, p 47 (2018)
Proteomes
Volume 6
Issue 4
Proteomes
Volume 6
Issue 4
Paraquat is a potent superoxide (O2&minus
)-inducing agent that is capable of inducing an oxidative imbalance in the mosquito midgut. This oxidative imbalance can super-stress the malaria parasite, leading to arrested development in the mosquito
)-inducing agent that is capable of inducing an oxidative imbalance in the mosquito midgut. This oxidative imbalance can super-stress the malaria parasite, leading to arrested development in the mosquito
Autor:
Stefan M. Kanzok, Katherine Fell, Kenneth W. Olsen, Kyle J. Haselton, Emily Schulte, Robin David, Matthew Dybas
Publikováno v:
Parasitology International. 64:282-289
Glutathione peroxidases (GPx) comprise an important group of redox active proteins with diverse functions, including antioxidant defense and signaling. Although the genome of the malaria parasite Plasmodium does not contain a genuine GPx gene a gluta