Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Stefan M Ivanov"'
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0224271 (2019)
Due to its high catalytic activity and readily available supply, ribonuclease A (RNase A) has become a pivotal enzyme in the history of protein science. Moreover, this great interest has carried over to computational chemistry and molecular dynamics,
Externí odkaz:
https://doaj.org/article/a5f81c433bc842ea8f2c019a7afda40c
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0185928 (2017)
An improved knowledge of protein-protein interactions is essential for better understanding of metabolic and signaling networks, and cellular function. Progress tends to be based on structure determination and predictions using known structures, alon
Externí odkaz:
https://doaj.org/article/3d614f4708f94dacbf8ad91b0eaf47c8
Autor:
Alexander D. MacKerell, Asma Rehman, Stefan M. Ivanov, Brian G. Pierce, Amanda S. Altieri, Wenbo Yu, S. Saif Hasan
Publikováno v:
Biophysical Journal. 120:210a-211a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea0a44d69cc2695bf97d0aa176e997e6
https://doi.org/10.1016/j.bpj.2020.11.1427
https://doi.org/10.1016/j.bpj.2020.11.1427
Publikováno v:
Ivanov, S M, Huber, R G, Alibay, I, Warwicker, J & Bond, P J 2019, ' Energetic Fingerprinting of Ligand Binding to Paralogous Proteins : The Case of the Apoptotic Pathway ', Journal of Chemical Information and Modeling . https://doi.org/10.1021/acs.jcim.8b00765
Networks of biological molecules are key to cellular function, governing processes ranging from signal cascade propagation to metabolic pathway regulation. Genetic duplication processes give rise to sets of regulatory proteins that have evolved from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2c0b1204247cfe198f43b6aa1ce5b0d
https://doi.org/10.1021/acs.jcim.8b00765
https://doi.org/10.1021/acs.jcim.8b00765
Publikováno v:
Ivanov, S M, Huber, R G, Warwicker, J & Bond, P J 2016, ' Energetics and Dynamics Across the Bcl-2-Regulated Apoptotic Pathway Reveal Distinct Evolutionary Determinants of Specificity and Affinity ', Structure (London, England : 1993), vol. 24, no. 11, pp. 2024-2033 . https://doi.org/10.1016/j.str.2016.09.006
Critical regulatory pathways are replete with instances of intra- and interfamily protein-protein interactions due to the pervasiveness of gene duplication throughout evolution. Discerning the specificity determinants within these systems has proven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f75e0dd7919d6835d50020a83012c6
https://pubmed.ncbi.nlm.nih.gov/27773689
https://pubmed.ncbi.nlm.nih.gov/27773689