Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Stefan Lindström"'
Autor:
Charlotta Lindquist, Stefan Lindström, Tse-I Lin, Magnus Nilsson, Tatiana Agback, Horst Wähling, Pierre Jean-Marie Bernard Raboisson, Mikael Pelcman, Wigerinck Piet Tom Bert Paul, Pia Cecilia Kahnberg, Kurt Benkestock, Herman de Kock, Michael Edlund, Anders Eneroth, Elizabeth Hamelink, Anna Karin Belfrage, Susana Ayesa, Ylva Terelius, Kristina Wikström, Åsa Rosenquist, Lotta Vrang, Kenneth Simmen, Bertil Samuelsson, Christina Rydergård
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:4004-4011
Novel NS3/4A protease inhibitors comprising quinazoline derivatives as P2 substituent were synthesized. High potency inhibitors displaying advantageous PK properties have been obtained through the optimization of quinazoline P2 substituents in three
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bd304710cfabba8d5ae2d3233ceb229
https://doi.org/10.1016/j.bmcl.2010.05.029
https://doi.org/10.1016/j.bmcl.2010.05.029
Autor:
Michael Edlund, Oliver Lenz, Pia Cecilia Kahnberg, Stefan Lindström, Frederic Delouvroy, Dominique Louis Nestor Ghislain Surleraux, Magnus Nilsson, Dmitry Antonov, Anders Eneroth, Wim Van De Vreken, Kristina Wikström, Tse-I Lin, Piet Wigerinck, Kenneth Simmen, Vladimir Ivanov, Marleen Van Dooren, Susana Ayesa, Hu Lili, Abdellah Tahri, Åsa Rosenquist, Lotta Vrang, Per-Ola Johansson, Vendeville Sandrine Marie Hele, Herman de Kock, Pierre Raboisson, Bertil Samuelsson, Björn Classon, Natalie Maria Francisca Kindermans, David McGowan
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:6189-6193
A novel series of P3-truncated macrocyclic HCV NS3/4A protease inhibitors containing a P2 proline-urea or carbamate scaffold was synthesized. Very potent inhibitors were obtained through the optimization of the macrocycle size, urea and proline subst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ca19d51213a5c97bb70d21813a4cd8
https://doi.org/10.1016/j.bmcl.2008.10.004
https://doi.org/10.1016/j.bmcl.2008.10.004
Autor:
Christina Rydergård, Hans Wallberg, Björn Classon, Åsa Rosenquist, Stefan Lindström, Elizabeth Hamelink, Per-Ola Johansson, Bertil Samuelsson, Ingemar Kvarnström, Fredrik Thorstensson, Susana Ayesa, Anders Hallberg, Fredrik Wångsell, Mikael Pelcman, Horst Wähling, Marcus Bäck, Katarina Jansson, Lotta Vrang
Publikováno v:
Bioorganic & Medicinal Chemistry. 15:7184-7202
Several highly potent novel HCV NS3 protease inhibitors have been developed from two inhibitor series containing either a P2 trisubstituted macrocyclic cyclopentane- or a P2 cyclopentene dicarboxylic acid moiety as surrogates for the widely used N-ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15921dd4d5e74960f57d655a5ff961ae
https://doi.org/10.1016/j.bmc.2007.07.027
https://doi.org/10.1016/j.bmc.2007.07.027
Autor:
Spiros Grivas, Stefan Lindström
Publikováno v:
Journal of Heterocyclic Chemistry. 32:467-471
The tetrakis(triphenylphosphine)palladium(O)-catalyzed coupling of benzeneboronic acid with 2-chloro, 6-bromo and 6-bromo-2-chloro derivatives of 1- and 3-methylimidazo[4,5-b]pyridines to novel 2-phenyl-, 6-phenyl- and 2,6-diphenylimidazo[4,5-b]pyrid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9725c8af8d8f8b47e43f9eee7826f193
https://doi.org/10.1002/jhet.5570320214
https://doi.org/10.1002/jhet.5570320214
Autor:
Mikael Eriksson, Teddy K. Thorsen, Anne K. Jensen, Philip Coppens, Spiros Grivas, Ole Buchardt, Stefan Lindström
Publikováno v:
Acta Chemica Scandinavica. 47:805-812
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa11d45936110276ba1cdfd9a799fd69
https://doi.org/10.3891/acta.chem.scand.47-0805
https://doi.org/10.3891/acta.chem.scand.47-0805
Autor:
Erik Ronne, Tadashi Tsuda, Pekka Pietikäinen, Ahmad Nasiri, Harri Setälä, Kjell Olsson, Marit Trætteberg, Lise Falborg, Stefan Lindström, Alexander Senning
Publikováno v:
Acta Chemica Scandinavica. 47:514-520
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d28fb9ba6161503e6ba5919193da2390
https://doi.org/10.3891/acta.chem.scand.47-0514
https://doi.org/10.3891/acta.chem.scand.47-0514
Autor:
Marit Trætteberg, Wei Tian, Pekka Pietikäinen, Erik Ronne, Ahmad Nasiri, Stefan Lindström, Tadashi Tsuda, Kjell Olsson, Harri Setälä, Spiros Grivas
Publikováno v:
Acta Chemica Scandinavica. 47:521-528
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::229daf3b12c1abd6927f399a64bb6642
https://doi.org/10.3891/acta.chem.scand.47-0521
https://doi.org/10.3891/acta.chem.scand.47-0521
Autor:
Kjell Olsson, Harri Setälä, Erik Ronne, Ahmad Nasiri, K.-M. Marstokk, Harald Møllendal, Marit Trætteberg, Pekka Pietikäinen, Tadashi Tsuda, Stefan Lindström
Publikováno v:
Acta Chemica Scandinavica. 47:444-448
The microwave spectra of title compound and one deuterated species (hydroxyl group) have been investigated in the 26.0-39.0 GHz spectral region at about 0°C. One conformer with a six-membered intramolecular hydrogen bond formed between the hydrogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbdf8ddc8697e06e339b68d61a6c50af
https://doi.org/10.3891/acta.chem.scand.47-0444
https://doi.org/10.3891/acta.chem.scand.47-0444
Publikováno v:
Organic Letters. 2:2291-2293
The anabasine analogues spiro[4-azaindan-1,2'-piperidine] (7) and spiro[6-azaindan-1,2'-piperidine] (8) have been prepared. A series of palladium-catalyzed reactions, where an intramolecular cyclization constituted a key reaction, were utilized for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91af76d1f673b5410d6618531410e6fc
https://doi.org/10.1021/ol006056f
https://doi.org/10.1021/ol006056f
Autor:
Stefan Lindström, Per Ahlberg, Ingrid Forsblom, Eva Johansson, Charlotta Lundberg, Jan Arnarp, Lars Björk, Ryszard Gawinecki
Publikováno v:
Acta chemica Scandinavica (Copenhagen, Denmark : 1989). 49(5)
2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine has been prepared in 26% yield from 3-amino-2-phenylpropenal and creatinine which were heated with N,O-bis(trimethylsilyl)acetamide at 120 degrees C for 2 h. Under certain other conditions, the main pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b7468c1d7053e243d2182503918ed3c
https://pubmed.ncbi.nlm.nih.gov/7766463
https://pubmed.ncbi.nlm.nih.gov/7766463