Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Stefan Lehnert"'
Autor:
Laura Yissel Rengifo, Sanne Smits, Lieselot Buedts, Michel Delforge, Luc Dehaspe, Thomas Tousseyn, Nancy Boeckx, Stefan Lehnert, Lucienne Michaux, Joris Robert Vermeesch, Peter Vandenberghe, Barbara Dewaele
Publikováno v:
Cancer Treatment and Research Communications, Vol 28, Iss , Pp 100380- (2021)
Multiple myeloma (MM), is a heterogeneous disease in which chromosomal abnormalities are important for prognostic risk stratification. Cytogenetic profiling with FISH on plasma cells from bone marrow samples (BM-PCs) is the current gold standard, but
Externí odkaz:
https://doaj.org/article/85c27e840f814546b405842cb93ef777
Autor:
Roel Quintens, Sarvjeet Singh, Katleen Lemaire, Katrien De Bock, Mikaela Granvik, Anica Schraenen, Irene Olga Cornelia Maria Vroegrijk, Veronica Costa, Pieter Van Noten, Dennis Lambrechts, Stefan Lehnert, Leentje Van Lommel, Lieven Thorrez, Geoffroy De Faudeur, Johannes Anthonius Romijn, John Michael Shelton, Luca Scorrano, Henri Roger Lijnen, Peter Jacobus Voshol, Peter Carmeliet, Pradeep Puthenveetil Abraham Mammen, Frans Schuit
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56719 (2013)
Oxidative phosphorylation in mitochondria is responsible for 90% of ATP synthesis in most cells. This essential housekeeping function is mediated by nuclear and mitochondrial genes encoding subunits of complex I to V of the respiratory chain. Althoug
Externí odkaz:
https://doaj.org/article/6e48974138964287b15012c484cb8268
Autor:
Patrick Oeckl, Petra Steinacker, Stefan Lehnert, Sarah Jesse, Hans A Kretzschmar, Albert C Ludolph, Markus Otto, Boris Ferger
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32664 (2012)
BackgroundThe cyclic nucleotides cyclic adenosine-3',5'-monophosphate (cAMP) and cyclic guanosine-3',5'-monophosphate (cGMP) are important second messengers and are potential biomarkers for Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS
Externí odkaz:
https://doaj.org/article/3ca108ae1354458b855b29fa89919062
Autor:
Sarah Jesse, Stefan Lehnert, Olaf Jahn, Lucilla Parnetti, Hilkka Soininen, Sanna-Kaisa Herukka, Petra Steinacker, Saskia Tawfik, Hayrettin Tumani, Christine A F von Arnim, Manuela Neumann, Hans A Kretzschmar, Hasan Kulaksiz, Martin Lenter, Jens Wiltfang, Boris Ferger, Bastian Hengerer, Markus Otto
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48783 (2012)
The prevalence of Parkinson's disease (PD) increases with age. Up to 50% of PD show cognitive decline in terms of a mild cognitive impairment already in early stages that predict the development of dementia, which can occur in up to 80% of PD patient
Externí odkaz:
https://doaj.org/article/96e0f187c2d94eceb793dce61c31338f
Autor:
Sarah Jesse, Petra Steinacker, Stefan Lehnert, Martin Sdzuj, Lukas Cepek, Hayrettin Tumani, Olaf Jahn, Holger Schmidt, Markus Otto
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10079 (2010)
BACKGROUND: The discrimination of bacterial meningitis (BM) versus viral meningitis (VM) shapes up as a problem, when laboratory data are not equivocal, in particular, when Gram stain is negative. METHODOLOGY/PRINCIPAL FINDINGS: With the aim to deter
Externí odkaz:
https://doaj.org/article/1f2a21c6387942c3ac2e6e354c1b0381
Autor:
Stefan Lehnert, Peter Van Loo, Pushpike J Thilakarathne, Peter Marynen, Geert Verbeke, Frans C Schuit
Publikováno v:
PLoS ONE, Vol 4, Iss 2, p e4456 (2009)
This paper connects Alu repeats, the most abundant repetitive elements in the human genome and microRNAs, small RNAs that alter gene expression at the post-transcriptional level. Base-pair complementarity could be demonstrated between the seed sequen
Externí odkaz:
https://doaj.org/article/a33286440be04c1e99d4f0f7acf572cc
Autor:
Annouschka Laenen, Jasper Victoor, Lien Spans, Ignace Vergote, Els Van Nieuwenhuysen, Hilde Brems, Isabelle Vanden Bempt, Anne-Sophie Van Rompuy, Toon Van Gorp, Stefan Timmerman, Stefan Lehnert, Sara Vander Borght, Sileny Han
Publikováno v:
Gynecologic Oncology. 162:694-701
Objective Combined immunohistochemical and molecular classification using the Proactive Molecular Risk Classifier for Endometrial Cancer (ProMisE) independently predicts prognosis in endometrial carcinoma (EC). As next-generation sequencing (NGS) is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27bd869beb45097c0888f25a3a9542dc
https://doi.org/10.1016/j.ygyno.2021.06.030
https://doi.org/10.1016/j.ygyno.2021.06.030
Autor:
Michel Delforge, Peter Vandenberghe, Nancy Boeckx, Barbara Dewaele, Thomas Tousseyn, Jia Ding, G Ameye, Joris Vermeesch, Lucienne Michaux, Stefan Lehnert, Sanne Smits, Lieselot Buedts
Publikováno v:
Genes, Chromosomes and Cancer. 59:465-471
Cytogenetic abnormalities are powerful prognostic factors in multiple myeloma (MM) and are routinely analyzed by FISH on bone marrow (BM) plasma cells (PC). Although considered the gold standard, FISH experiments can be laborious and expensive. There
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5f6edae8482197e7c486a4f2d981604
https://doi.org/10.1002/gcc.22848
https://doi.org/10.1002/gcc.22848
Autor:
Sara Vander Borght, Isabelle Vanden Bempt, Ragna Vanslembrouck, Patrick Schöffski, Stefan Lehnert, Mathilde Gheysen
Publikováno v:
Oncology Research and Treatment. 43:470-473
Introduction: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract and the most frequent sarcomas in some geographic regions. In patients with metastatic GIST, the tyrosine kinase inhibitor imat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ff0780ea8fbf7e40186a566dec1376a
https://doi.org/10.1159/000508536
https://doi.org/10.1159/000508536
Autor:
Sofie Claerhout, Stefan Lehnert, Sara Vander Borght, Lien Spans, Christophe Dooms, Els Wauters, Johan Vansteenkiste, Birgit Weynand, Karen Deraedt, Claire Bourgain, Isabelle Vanden Bempt
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 166
Targeted RNA-based Next-Generation Sequencing (tRNA-seq) is increasingly being used in molecular diagnostics for gene fusion detection in non-small cell lung cancer (NSCLC). However, few data support its clinical application for the detection of sing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e962338cae30a409e986c13ccff5f835
https://pubmed.ncbi.nlm.nih.gov/35378489
https://pubmed.ncbi.nlm.nih.gov/35378489