Zobrazeno 1 - 10
of 594
pro vyhledávání: '"Stefan Laufer"'
Publikováno v:
Advanced Sensor Research, Vol 3, Iss 10, Pp n/a-n/a (2024)
Abstract The age of antibiotics, which began with the discovery of penicillin in 1929, marks an important period in medical history, as deadly bacterial infections seemed to be a thing of the past. However, the tide turned as more and more resistance
Externí odkaz:
https://doaj.org/article/2d3fbabddb4f4903ab7ca89fc5c95f78
Autor:
Carla Fernanda Furtado Gardani, Fernando Mendonça Diz, Luísa Brandalise Dondé, Liliana Rockenbach, Stefan Laufer, Fernanda Bueno Morrone
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Purines and pyrimidines are signaling molecules in the tumor microenvironment that affect cancer immunity. The purinergic signaling pathways have been shown to play an important role in the development and progression of cancer. CD39 and CD73 are ect
Externí odkaz:
https://doaj.org/article/a212efaf8ba745b8ad62c31a4f892f44
Publikováno v:
Advanced Science, Vol 11, Iss 21, Pp n/a-n/a (2024)
Abstract One of the most important public health concerns is the increase in antibiotic‐resistant pathogens and corresponding treatment of associated infections. Addressing this challenge requires more efficient use of antibiotics, achievable by th
Externí odkaz:
https://doaj.org/article/0176c542c043492e8254d9f2652274f2
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-18 (2022)
Abstract Background In vivo-mimicking conditions are critical in in vitro cell analysis to obtain clinically relevant results. The required conditions, comparable to those prevalent in nature, can be provided by microfluidic dynamic cell cultures. Mi
Externí odkaz:
https://doaj.org/article/18c79587ab08458aa0305dc96d60efed
Autor:
Oliver Riester, Pia Burkhardtsmaier, Yuna Gurung, Stefan Laufer, Hans-Peter Deigner, Magnus S. Schmidt
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract The widespread use of antibiotics in recent decades has been a major factor in the emergence of antibiotic resistances. Antibiotic-resistant pathogens pose increasing challenges to healthcare systems in both developing and developed countrie
Externí odkaz:
https://doaj.org/article/5f8213b359d7406e82d413c0e211e97c
Autor:
Manuel Keppler, Simon Straß, Sophia Geiger, Tina Fischer, Nadja Späth, Thilo Weinstein, Anna Schwamborn, Jamil Guezguez, Jan-Hinrich Guse, Stefan Laufer, Michael Burnet
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
TLR Agonists have promising activity in preclinical models of viral infection and cancer. However, clinical use is only in topical application. Systemic uses of TLR-ligands such as Resiquimod, have failed due to adverse effects that limited dose and
Externí odkaz:
https://doaj.org/article/8483e3fbceb94d0594311121d3713c86
Autor:
Anne-Katrin Rohlfing, Kyra Kolb, Manuel Sigle, Melanie Ziegler, Alexander Bild, Patrick Münzer, Jessica Sudmann, Valerie Dicenta, Tobias Harm, Mailin-Christin Manke, Sascha Geue, Marcel Kremser, Madhumita Chatterjee, Chunguang Liang, Hendrik von Eysmondt, Thomas Dandekar, David Heinzmann, Manina Günter, Saskia von Ungern-Sternberg, Manuela Büttcher, Tatsiana Castor, Stine Mencl, Friederike Langhauser, Katharina Sies, Diyaa Ashour, Mustafa Caglar Beker, Michael Lämmerhofer, Stella E. Autenrieth, Tilman E. Schäffer, Stefan Laufer, Paulina Szklanna, Patricia Maguire, Matthias Heikenwalder, Karin Anne Lydia Müller, Dirk M. Hermann, Ertugrul Kilic, Ralf Stumm, Gustavo Ramos, Christoph Kleinschnitz, Oliver Borst, Harald F. Langer, Dominik Rath, Meinrad Gawaz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
ACKR3 is a critical regulator of platelet-mediated thrombosis and organ injury following ischemia/reperfusion. Platelet ACKR3 surface expression is independently associated with all-cause mortality in patients with cardiovascular diseases.
Externí odkaz:
https://doaj.org/article/bff45f142b4844968bc8a69ceae8231a
Autor:
Fatma Al-Rubaiai, Zakiya Zahran Al-Shariqi, Khalsa S. Al-Shabibi, John Husband, Asmaa M. Al-Hattali, Marcia Goettert, Stefan Laufer, Younis Baqi, Syed Imran Hassan, Majekodunmi O. Fatope
Publikováno v:
Molecules, Vol 28, Iss 16, p 6077 (2023)
Maytenus dhofarensis Sebsebe (Celestraceae) is a naturally growing shrub in Oman. It is not a reputed medicinal plant in Oman, but it is regionally endemic and causes shivering attacks on goats that graze on it. The chemical investigation of the hexa
Externí odkaz:
https://doaj.org/article/a6184f3a3db9437cba04066cbd899d4f
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Magnetotactic bacteria are microscale complex natural systems that synthesize magnetic nanoparticles through biologically controlled mineralization. Nanoparticles produced by this process are biocompatible due to the presence of surrounding
Externí odkaz:
https://doaj.org/article/f284a4877a6b4cd890a4e4dce6e04f7a
Autor:
Nathália Grave, Thamiris Becker Scheffel, Fernanda Fernandes Cruz, Liliana Rockenbach, Márcia Inês Goettert, Stefan Laufer, Fernanda Bueno Morrone
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Gliomas are extremely debilitating malignant brain tumors with very limited response to therapies. The initiation and progression of gliomas can be attributed to several molecular abnormalities, such as mutations in important regulatory networks. In
Externí odkaz:
https://doaj.org/article/9f9d0fbf2ae44aa2aab2855abada4425