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pro vyhledávání: '"Stefan Löhrke"'
Dieser Sammelband befasst sich mit Herausforderungen des Qualitätsmanagements im Bereich von Studium und Hochschullehre. Sie reichen von der Leitbildentwicklung, der Steuerung entlang von Zielen, der Errichtung effektiver Strukturen bis hin zur Erri
Autor:
Nadine Braun, Katrin Janz, Stefan Löhrke, Eckhard Friauf, Jan J. Hirtz, Christian Hannes, Britta Müller, Désirée Griesemer
Publikováno v:
The Journal of Neuroscience. 32:14602-14616
Synaptic refinement via the elimination of inappropriate synapses and strengthening of appropriate ones is crucially important for the establishment of specific, topographic neural circuits. The mechanisms driving these processes are poorly understoo
Publikováno v:
Brain Research. 1295:21-36
Spontaneous activity occurs in the mammalian auditory system prior to hearing onset and is relevant for neuronal differentiation. Growing evidence indicates that miniature events, i.e., action potential-independent synaptic activity, also have some d
Autor:
Martin Oberhofer, Veeramuthu Balakrishnan, Meike Wenz, Marlies Knipper, Hans Gerd Nothwang, Stefan Löhrke, Eckhard Friauf
Publikováno v:
European Journal of Neuroscience. 28:2371-2380
Thyroid hormone (TH) deficiency during perinatal life causes a multitude of functional and morphological deficits in the brain. In rats and mice, TH dependency of neural maturation is particularly evident during the first 1-2 weeks of postnatal devel
Publikováno v:
European Journal of Neuroscience. 22:2708-2722
The inhibitory transmitters glycine and GABA undergo a developmental shift from depolarizing to hyperpolarizing action (D ⁄ H-shift). To analyse this shift in functionally related nuclei of the rat superior olivary complex (SOC), we employed voltag
Publikováno v:
Journal of Neurobiology. 59:272-288
A functional analysis of AMPA and kainate receptors (AMPARs and KARs) in the lateral superior olive (LSO), a major nucleus in the auditory brainstem, has not been performed so far, to our knowledge. Here we investigated the presence and characteristi
Publikováno v:
Neuroscience. 128:617-634
Superior olivary complex (SOC) neurons receive excitatory and inhibitory inputs from both ears. We determined the nature of such inputs to the main SOC nuclei with an optical imaging system. To do so, brainstem slices of postnatal (P) rats (P3–13)
Autor:
Veeramuthu Balakrishnan, Stefan Löhrke, Erdem Güresir, Michael P.I. Becker, Eckhard Friauf, Hans Gerd Nothwang
Publikováno v:
Scopus-Elsevier
Glycine and GABA, the dominant inhibitory neurotransmitters in the CNS, assume a depolarizing role in early development, leading to increased cytoplasmic Ca2+levels and action potentials. The effect is thought to be of some significance for maturatio
Autor:
Stefan Löhrke, Eckhard Friauf
Publikováno v:
Cell and Tissue Research. 308:19-33
The medial nucleus of the trapezoid body (MNTB) acts as a relay nucleus in the transmission of auditory information from the cochlear nucleus (CN) to the lateral superior olive. Glutamate receptors mediate the excitatory synaptic transmission in the
Publikováno v:
The Journal of Physiology. 520:121-137
1. The inhibitory neurotransmitter glycine can elicit depolarizing responses in immature neurones. We investigated the changes in glycine responses and their ionic mechanism in developing neurones of the rat lateral superior olive (LSO), an auditory