Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Stefan Kustermann"'
Autor:
Madalena Cipriano, Katharina Schlünder, Christopher Probst, Kirstin Linke, Martin Weiss, Mona Julia Fischer, Lena Mesch, Kevin Achberger, Stefan Liebau, Marina Mesquida, Valeria Nicolini, Anneliese Schneider, Anna Maria Giusti, Stefan Kustermann, Peter Loskill
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
To address the key physiological characteristics related to choroidal drug reactions and its immunology, Cipriano et al. developed a human immunocompetent choroidal in vitro model that mimics the tissue vascularization, pigmentation and immune respon
Externí odkaz:
https://doaj.org/article/947bc0fd7c1d4021ac050c034f4c9b24
Autor:
Sebastiaan J. Trietsch, Elena Naumovska, Dorota Kurek, Meily C. Setyawati, Marianne K. Vormann, Karlijn J. Wilschut, Henriëtte L. Lanz, Arnaud Nicolas, Chee Ping Ng, Jos Joore, Stefan Kustermann, Adrian Roth, Thomas Hankemeier, Annie Moisan, Paul Vulto
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Efforts to determine the effects of drugs on epithelial barriers could benefit from better in vitro models. Here the authors develop a microfluidic device supporting the growth and function of extracellular matrix-supported intestinal tubules, and ev
Externí odkaz:
https://doaj.org/article/936a946cd151424cbb470b23c064cef4
Autor:
Christian Ruiz, Stefan Kustermann, Elina Pietilae, Tatjana Vlajnic, Betty Baschiera, Leila Arabi, Thomas Lorber, Martin Oeggerli, Spasenija Savic, Ellen Obermann, Thomas Singer, Sacha I Rothschild, Alfred Zippelius, Adrian B Roth, Lukas Bubendorf
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160807 (2016)
The use of patients' own cancer cells for in vitro selection of the most promising treatment is an attractive concept in personalized medicine. Human carcinoma cells from malignant pleural effusions (MPEs) are suited for this purpose since they have
Externí odkaz:
https://doaj.org/article/978afa43d8174d57b35ed16f87948089
Autor:
Valeria Chichagova, Maria Georgiou, Madeleine Carter, Birthe Dorgau, Gerrit Hilgen, Joseph Collin, Rachel Queen, Git Chung, Jila Ajeian, Marina Moya‐Molina, Stefan Kustermann, Francois Pognan, Philip Hewitt, Michael Schmitt, Evelyne Sernagor, Lyle Armstrong, Majlinda Lako
Publikováno v:
Journal of Cellular and Molecular Medicine. 27:435-445
Autor:
Tianyi Jiang, Stefan Kustermann, Xiaoqin Wu, Christine Zihlmann, Meifang Zhang, Yi Mao, Waikwong Wu, Jianxun Xie
Publikováno v:
Molecular & Cellular Toxicology. 19:333-342
Autor:
Martin Bopst, Theo Dinklo, Juergen Funk, Andrea Greiter-Wilke, Barbara Lenz, Stefan Kustermann, Tianyi Jiang, Jianxun Xie
Publikováno v:
Regulatory Toxicology and Pharmacology. 141:105407
Autor:
Manuela Jaklin, Nicole Clemann, Marcel Leist, Paul Barrow, Stefan Kustermann, Jitao David Zhang, Martin Ebeling
Publikováno v:
Reproductive Toxicology. 98:286-298
Human induced pluripotent stem cells (hiPSC) were used to develop an assay format that may deliver information on teratogenicity of drugs. A human pluripotent stem cell scorecard panel was used to monitor the expression of 96 marker genes that are in
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2475
Relevant human in vitro models of the retinal microvasculature can be used to study the role of disease mediators on retinal barrier dysfunction and assess the efficacy of early drug candidates. This chapter describes an organ-on-a-chip model of the
Autor:
Stefan Kustermann, Carla Johanna Plüss
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics. 36:56-64
Purpose: Cataract is a pathological opacification of the lens, which is still one of the leading causes of blindness in the world. Several etiologies are described, among them drug-induced cataract, for example, posterior subcapsular cataract (PSC) a
Autor:
Schluender K, M. Mesquida, Lena Mesch, Christopher Probst, Stefan Liebau, Fischer Mj, Magdalene Weiss, Anneliese Schneider, Peter Loskill, Stefan Kustermann, Nicolini, Madalena Cipriano, Kevin Achberger, Linke K, Giusti Am
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Communications Biology
Communications Biology
Disorders of the eye leading to visual impairment are a major issue that affects millions of people. On the other side ocular toxicities were described for e.g. molecularly targeted therapies in oncology and may hamper their development. Current ocul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e7716448751ef68ae47a37d360d1498
https://publica.fraunhofer.de/handle/publica/429531
https://publica.fraunhofer.de/handle/publica/429531