Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Stefan Kurtenbach"'
Autor:
Markus Spurlock, Weijun An, Galina Reshetnikova, Rong Wen, Hua Wang, Michelle Braha, Gabriela Solis, Stefan Kurtenbach, Orlando J. Galindez, Juan Pablo de Rivero Vaccari, Tsung-Han Chou, Vittorio Porciatti, Valery I. Shestopalov
Publikováno v:
Cells, Vol 12, Iss 22, p 2626 (2023)
The dysfunction and selective loss of retinal ganglion cells (RGCs) is a known cause of vision loss in glaucoma and other neuropathies, where ocular hypertension (OHT) is the major risk factor. We investigated the impact of transient non-ischemic OHT
Externí odkaz:
https://doaj.org/article/b7c16fccb0604e06baa7cbb92d4a88e0
Autor:
Anna Han, Dzmitry Mukha, Vivian Chua, Timothy J. Purwin, Manoela Tiago, Bhavik Modasia, Usman Baqai, Jenna L. Aumiller, Nelisa Bechtel, Emily Hunter, Meggie Danielson, Mizue Terai, Philip B. Wedegaertner, Takami Sato, Solange Landreville, Michael A. Davies, Stefan Kurtenbach, J. William Harbour, Zachary T. Schug, Andrew E. Aplin
Publikováno v:
Cancers, Vol 15, Iss 13, p 3451 (2023)
Uveal melanoma (UM) displays a high frequency of metastasis; however, effective therapies for metastatic UM are limited. Identifying unique metabolic features of UM may provide a potential targeting strategy. A lipid metabolism protein expression sig
Externí odkaz:
https://doaj.org/article/bd1520908be04ad1b023ec228e9a8999
Autor:
Stefan Kurtenbach, Anthony M. Cruz, Daniel A. Rodriguez, Michael A. Durante, J. William Harbour
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-3 (2021)
Abstract Background Recent advances in single cell sequencing technologies allow for greater resolution in assessing tumor clonality using chromosome copy number variations (CNVs). While single cell DNA sequencing technologies are ideal to identify t
Externí odkaz:
https://doaj.org/article/df6ab85ee0b24705b154f076fdadfcc9
Autor:
Michael A. Durante, Daniel A. Rodriguez, Stefan Kurtenbach, Jeffim N. Kuznetsov, Margaret I. Sanchez, Christina L. Decatur, Helen Snyder, Lynn G. Feun, Alan S. Livingstone, J. William Harbour
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Uveal melanoma is highly metastatic and unresponsive to checkpoint immunotherapy. Here, the authors present single-cell transcriptomics of 59,915 cells in 8 primary and 3 metastatic samples, highlighting the diversity of the tumour microenvironment.
Externí odkaz:
https://doaj.org/article/44e8def81b794cf189b9ab19348ac21d
Autor:
Michelle G. Zhang, Jeffim N. Kuznetsoff, Dawn A. Owens, Ryan A. Gallo, Karthik Kalahasty, Anthony M. Cruz, Stefan Kurtenbach, Zelia M. Correa, Daniel Pelaez, J. William Harbour
Publikováno v:
Cancers, Vol 14, Iss 19, p 4966 (2022)
Retinoblastoma is the most common eye cancer in children and is fatal if left untreated. Over the past three decades, chemotherapy has become the mainstay of eye-sparing treatment. Nevertheless, chemoresistance continues to represent a major challeng
Externí odkaz:
https://doaj.org/article/29655fe527c64241ab7ab59fe245f8c9
Autor:
Christopher J. Kaler, James J. Dollar, Anthony M. Cruz, Jeffim N. Kuznetsoff, Margaret I. Sanchez, Christina L. Decatur, Jonathan D. Licht, Keiran S. M. Smalley, Zelia M. Correa, Stefan Kurtenbach, J. William Harbour
Publikováno v:
Cancers, Vol 14, Iss 15, p 3678 (2022)
Uveal melanoma (UM) is the most common primary cancer of the eye and is associated with a high rate of metastatic death. UM can be stratified into two main classes based on metastatic risk, with class 1 UM having a low metastatic risk and class 2 UM
Externí odkaz:
https://doaj.org/article/e65180ed85fb4a6d93d7f4923bfd84d0
Autor:
Matthew G. Field, Michael A. Durante, Hima Anbunathan, Louis Z. Cai, Christina L. Decatur, Anne M. Bowcock, Stefan Kurtenbach, J. William Harbour
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Uveal melanoma (UM), the most common primary eye cancer, is strongly linked to mutations in the tumor suppressor BAP1. Here, the authors analyze 151 primary UM samples to find that BAP1 and other canonical genomic aberrations arise in an early punctu
Externí odkaz:
https://doaj.org/article/08030f7ca35741a99b1860d184fb1194
Autor:
Stefan Kurtenbach, Andreas Gießl, Siv Strömberg, Jan Kremers, Jenny Atorf, Sebastian Rasche, Eva M. Neuhaus, Denis Hervé, Johann Helmut Brandstätter, Esther Asan, Hanns Hatt, Manfred W. Kilimann
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-19 (2017)
Abstract BEACH domain proteins are involved in membrane protein traffic and human diseases, but their molecular mechanisms are not understood. The BEACH protein LRBA has been implicated in immune response and cell proliferation, and human LRBA mutati
Externí odkaz:
https://doaj.org/article/3f19e8543c154b8eb7ffd756b3258257
Autor:
Paige Whyte-Fagundes, Stefan Kurtenbach, Christiane Zoidl, Valery I. Shestopalov, Peter L. Carlen, Georg Zoidl
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Pannexins (Panx) are integral membrane proteins, with Panx1 being the best-characterized member of the protein family. Panx1 is implicated in sensory processing, and knockout (KO) animal models have become the primary tool to investigate the role(s)
Externí odkaz:
https://doaj.org/article/60624e01bbb74fabb310df50cba68518
Autor:
Nora Prochnow, Amr Abdulazim, Stefan Kurtenbach, Verena Wildförster, Galina Dvoriantchikova, Julian Hanske, Elisabeth Petrasch-Parwez, Valery I. Shestopalov, Rolf Dermietzel, Denise Manahan-Vaughan, Georg Zoidl
Publikováno v:
PLoS ONE, Vol 8, Iss 1 (2013)
Externí odkaz:
https://doaj.org/article/5c9d6eca40dc4628a274b1a0b618a5aa