Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Stefan Krienke"'
Autor:
Inga Viktoria Hensel, Szabolcs Éliás, Michelle Steinhauer, Bilgenaz Stoll, Salvatore Benfatto, Wolfgang Merkt, Stefan Krienke, Hanns-Martin Lorenz, Jürgen Haas, Brigitte Wildemann, Martin Resnik-Docampo
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 3, Pp 547-574 (2024)
Abstract Human intestinal epithelial cells are the interface between luminal content and basally residing immune cells. They form a tight monolayer that constantly secretes mucus creating a multilayered protective barrier. Alterations in this barrier
Externí odkaz:
https://doaj.org/article/b7aabe92d90649c6adf10c4fefcf4995
Autor:
Lars Tykocinski, Carolin Birr, Marc-Steffen Raab, Stefan Krienke, Petra Schiller, Christine Tucher, Hanns Martin Lorenz, Norbert Blank, Laura Claßen, Felix Wiedmann, Martin Schiller
Publikováno v:
European Journal of Immunology. 47:1535-1549
Cell activation and apoptosis lead to the formation of extracellular vesicles (EVs) such as exosomes or microvesicles (MVs). EVs have been shown to modulate immune responses; recently, MVs were described to carry microRNA (miRNA) and a role for MVs i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2278cdfc8f4811d96de93f2124970de2
https://doi.org/10.1002/eji.201646595
https://doi.org/10.1002/eji.201646595
Autor:
Stefan Krienke, H.-M. Lorenz, R de Albuquerque Carvalho, M. Souto-Carneiro, L-O Tykocinski, P Kvacskay, T. Tretter, Karel D. Klika, J-H Schnotz
Publikováno v:
Poster presentations.
Introduction There is growing evidence for a dysregulated glucose metabolism of synovial fibroblasts (SF) in rheumatoid arthritis (RA) being a prerequisite for their aggressive phenotype. As yet, little is known about the influence of immune cells on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29aafcdce943ab29d4631dcdac48910c
https://doi.org/10.1136/annrheumdis-2018-ewrr2018.86
https://doi.org/10.1136/annrheumdis-2018-ewrr2018.86
Autor:
Christiane A. Opitz, Soumya R. Mohapatra, H.-M. Lorenz, Isabell Adam, L-O Tykocinski, N-C Kaul, Stefan Krienke
Publikováno v:
Abstracts Accepted for Publication.
Background The pathogenesis of rheumatoid arthritis (RA) is linked to functional changes in synovial fibroblasts (SF) and local infiltration of T lymphocytes. Increased synovial inflammation is also associated with a hypoxic joint microenvironment. O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d80c7c62059d481986efde5dfb027b5
https://doi.org/10.1136/annrheumdis-2017-eular.5146
https://doi.org/10.1136/annrheumdis-2017-eular.5146
Autor:
Hanns-Martin Lorenz, Stefan Krienke, Isabell Adam, Nathalie-Christin Kaul, Christine Tucher, Lars Oliver Tykocinski, Soumya R. Mohapatra, Christiane A. Opitz
Publikováno v:
Pathogenic stroma.
Background The development of rheumatoid arthritis (RA) is linked to changes in synovial fibroblasts’ (SF) phenotype and local infiltration of immune cells. In addition, hypoxic conditions are detected within the inflamed joints of RA patients. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f90de48e776be93f9541ac8aba95f9d
https://doi.org/10.1136/annrheumdis-2016-211051.11
https://doi.org/10.1136/annrheumdis-2016-211051.11
Autor:
Lars-Oliver Tykocinski, Anna M. Lauffer, Antonia Bohnen, Nathalie-Christin Kaul, Stefan Krienke, Theresa Tretter, Isabell Adam, Soumya R. Mohapatra, Philippe Saikali, Max Löhning, Michel Neidhart, Steffen Gay, Iris Oezen, Michael Platten, Christiane A. Opitz, Hanns-Martin Lorenz
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 198(8)
The development of rheumatoid arthritis (RA) is linked to functional changes in synovial fibroblasts (SF) and local infiltration of T lymphocytes. Fibroblasts possess the capacity to suppress T cell responses, although the molecular mechanisms of thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa12f2f02820c1b2dab719a2808b6c93
https://pubmed.ncbi.nlm.nih.gov/28264972
https://pubmed.ncbi.nlm.nih.gov/28264972
Autor:
Stefan Krienke, Sonja Kierschke, Hanna Marie Meesmann, Martin Herrmann, Eva-Marie Fehr, Martin Schiller, Hanns-Martin Lorenz, Petra Heyder, Norbert Blank, Rostyslav Bilyy
Publikováno v:
Journal of Cell Science. 123:3347-3356
The silent clearance of apoptotic cells is essential for cellular homeostasis in multicellular organisms, and several mediators of apoptotic cell recognition have been identified. However, the distinct mechanisms involved are not fully deciphered yet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc58aa1ffae16647f7f24d88fcd63498
https://doi.org/10.1242/jcs.066696
https://doi.org/10.1242/jcs.066696
Publikováno v:
The Journal of Rheumatology. 37:2369-2376
Objective.To analyze clinical manifestations, serum ferritin, and serum cytokine levels in patients with adult-onset Still’s disease (AOSD) or bacterial sepsis and to evaluate their potential use for differential diagnosis.Methods.Twenty-two consec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45cab3c48964d182b17475d79d351283
https://doi.org/10.3899/jrheum.100247
https://doi.org/10.3899/jrheum.100247
Autor:
Hanns-Martin Lorenz, Martin Schiller, Freja Busse, Joachim R. Kalden, Birgit Schätz, Norbert Blank, Stefan Krienke, Anthony D. Ho
Publikováno v:
The Journal of Immunology. 179:3613-3621
The localization of the TCR and other signaling molecules in membrane rafts (MR) is essential for the activation of T lymphocytes. MR are stabilized by sphingolipids and cholesterol. Activation of T lymphocytes leads to the confluence of small MR and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03ec2a6bb27b214e40c1dcd21b0085d5
https://doi.org/10.4049/jimmunol.179.6.3613
https://doi.org/10.4049/jimmunol.179.6.3613
Autor:
Hanns-Martin Lorenz, Lars-Oliver Tykocinski, Petra Heyder, Norbert Blank, Stefan Krienke, Martin Schiller, Anna Niessen
Publikováno v:
Journal of cell science. 128(14)
The dysregulation in clearance of apoptotic material is considered a major pathogenetic factor for the emergence of autoimmune diseases. Apoptotic cell-derived membrane microparticles (AdMPs), released from the cell surface during apoptosis, have bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6a078d4fd50c8daab97bac419268f2f
https://pubmed.ncbi.nlm.nih.gov/26034070
https://pubmed.ncbi.nlm.nih.gov/26034070