Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Stefan J. McCarver"'
Autor:
Nicholas I. Carruthers, Stefan J. McCarver, Chi Chip Le, Shireman Brock T, Russell T. Smith, Xiaheng Zhang, David W. C. MacMillan
Publikováno v:
Nature
Multicomponent reactions are relied on in both academic and industrial synthetic organic chemistry owing to their step- and atom-economy advantages over traditional synthetic sequences1. Recently, bicyclo[1.1.1]pentane (BCP) motifs have become valuab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc477e1b1996de0b83b589dc54963f83
http://europepmc.org/articles/PMC7148169
http://europepmc.org/articles/PMC7148169
Publikováno v:
Angewandte Chemie International Edition. 57:3488-3492
Herein we report a highly efficient method for nickel-catalyzed C–N bond formation between sulfonamides and aryl electrophiles. This technology provides generic access to a broad range of N-aryl and N-heteroaryl sulfonamide motifs, which are widely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b10689c76bbede635fd33d88ca402d
https://doi.org/10.1002/anie.201800699
https://doi.org/10.1002/anie.201800699
Autor:
Erik C. Hett, David W. C. MacMillan, James V. Oakley, Cory H. White, Tao Wang, Dann L. Parker, Tamara Reyes-Robles, Olugbeminiyi O. Fadeyi, Jacob B. Geri, Frances P. Rodriguez-Rivera, Stefan J. McCarver, Rob C. Oslund
Publikováno v:
Science (New York, N.Y.). 367(6482)
Pinpointing proteins To develop drugs that target a specific cell surface protein, it's helpful to know which other proteins reside in its vicinity. Geri et al. report a light-triggered labeling technique that improves the spatial resolution for this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcccc7c3d0f0493d2935a89122ef9777
https://pubmed.ncbi.nlm.nih.gov/32169879
https://pubmed.ncbi.nlm.nih.gov/32169879
Autor:
Jennifer X. Qiao, Michael M. Miller, Robert M. Borzilleri, Michael A. Poss, Joseph Carpenter, David W. C. MacMillan, Stefan J. McCarver, Martin D. Eastgate
Publikováno v:
Angewandte Chemie. 129:746-750
A method for the decarboxylative macrocyclization of peptides bearing N-terminal Michael acceptors has been developed. This synthetic method enables the efficient synthesis of cyclic peptides containing γ-amino acids and is tolerant of functionaliti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d453d17013bce5124fd6be04f2ce480
https://doi.org/10.1002/ange.201608207
https://doi.org/10.1002/ange.201608207
Publikováno v:
ChemInform. 46
A broad spectrum of carboxylic acids can be used in the reactions with iodides and bromides.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a8f124646c319a2b54efb8eaf36b681
https://doi.org/10.1002/chin.201527066
https://doi.org/10.1002/chin.201527066
Publikováno v:
Journal of the American Chemical Society
Decarboxylative cross-coupling of alkyl carboxylic acids with vinyl halides has been accomplished through the synergistic merger of photoredox and nickel catalysis. This new methodology has been successfully applied to a variety of α-oxy and α-amin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f235c94110d51f016537ebac3f245c9
https://pubmed.ncbi.nlm.nih.gov/25521443
https://pubmed.ncbi.nlm.nih.gov/25521443
An advanced intermediate in a projected synthesis of pactamycin has been prepared. Early installation of the C1-dimethylurea functionality allows for its participation in a diastereoselective, chelation-controlled addition of organometal nucleophiles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e09b984099844d79fbc0bfa3e5676f4a
Autor:
Geri, Jacob B., Oakley, James V., Reyes-Robles, Tamara, Wang, Tao, McCarver, Stefan J., White, Cory H., Rodriguez-Rivera, Frances P., Parker, Dann L., Hett, Erik C., Fadeyi, Olugbeminiyi O. olugbeminiyi.fadeyi@merck.com, Oslund, Rob C. rob.oslund@merck.com, MacMillan, David W. C. dmacmill@princeton.edu
Publikováno v:
Science. 3/6/2020, Vol. 367 Issue 6482, p1091-1097. 7p. 4 Diagrams.
Autor:
Kim, Taehoon1, McCarver, Stefan J.2, Lee, Chulbom1, MacMillan, David W. C.2 dmacmill@princeton.edu
Publikováno v:
Angewandte Chemie. 3/19/2018, Vol. 130 Issue 13, p3546-3550. 5p.
Autor:
McCarver, Stefan J.1, Qiao, Jennifer X.2, Carpenter, Joseph2, Borzilleri, Robert M.2, Poss, Michael A.2, Eastgate, Martin D.2, Miller, Michael M.2, MacMillan, David W. C.1 dmacmill@princeton.edu
Publikováno v:
Angewandte Chemie. 1/16/2017, Vol. 129 Issue 3, p746-750. 5p.