Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Stefan J. Jol"'
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 3, p e1002415 (2012)
One of the most obvious phenotypes of a cell is its metabolic activity, which is defined by the fluxes in the metabolic network. Although experimental methods to determine intracellular fluxes are well established, only a limited number of fluxes can
Externí odkaz:
https://doaj.org/article/c127d1a7eb514345ad8c53b989ce0a39
Publikováno v:
Mathematical and Computer Modelling of Dynamical Systems. 17:243-260
Construction of dynamic models of large-scale metabolic networks is one of the central issues in the engineering of living cells. However, construction of such models is often hampered by a number of challenges, for example, data availability, compar
Publikováno v:
Biophysical Journal, 99(10), 3139-3144. CELL PRESS
Thermodynamic analysis of metabolic networks has recently generated increasing interest for its ability to add constraints on metabolic network operation, and to combine metabolic fluxes and metabolite measurements in a mechanistic manner. Concepts f
Autor:
Matthias Heinemann, Anne Kümmel, Stefan J. Jol, Ruedi Aebersold, Paola Picotti, Uwe Sauer, Sarah-Maria Fendt, Jennifer C. Ewald, Nicola Zamboni
Publikováno v:
FEMS Yeast Research. 10:322-332
Under aerobic, high glucose conditions, Saccharomyces cerevisiae exhibits glucose repression and thus a predominantly fermentative metabolism. Here, we show that two commonly used prototrophic representatives of the CEN.PK and S288C strain families r
Temporal system-level organization of the switch from glycolytic to gluconeogenic operation in yeast
Autor:
Stefan J. Jol, Nicola Zamboni, Jennifer C. Ewald, Paola Picotti, Anne Kümmel, Guillermo G Zampar, Ruedi Aebersold, Uwe Sauer, Matthias Heinemann, Bastian Niebel
Publikováno v:
Molecular Systems Biology, 9:651. Wiley-Blackwell
Molecular Systems Biology
MOLECULAR SYSTEMS BIOLOGY
Molecular Systems Biology, 9 (1)
Molecular systems biology
Molecular Systems Biology
MOLECULAR SYSTEMS BIOLOGY
Molecular Systems Biology, 9 (1)
Molecular systems biology
Metabolome, proteome and physiology measurements were combined with mathematical modeling to unravel the temporal regulation of the metabolic fluxes during the diauxic shift in Saccharomyces cerevisiae.
The diauxic shift involves three main even
The diauxic shift involves three main even
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9949bf57c54ec6dc69119af1cddab7dc