Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Stefan J. Hermans"'
Autor:
Luke A. Miles, Stefan J. Hermans, Gabriela A.N. Crespi, Jonathan H. Gooi, Larissa Doughty, Tracy L. Nero, Jasmina Markulić, Andreas Ebneth, Berthold Wroblowski, Daniel Oehlrich, Andrés A. Trabanco, Marie-Laure Rives, Ines Royaux, Nancy C. Hancock, Michael W. Parker
Publikováno v:
iScience, Vol 19, Iss , Pp 110-118 (2019)
Summary: Polymorphism in the microglial receptor CD33 gene has been linked to late-onset Alzheimer disease (AD), and reduced expression of the CD33 sialic acid-binding domain confers protection. Thus, CD33 inhibition might be an effective therapy aga
Externí odkaz:
https://doaj.org/article/22f8a82eaea94df5bb89f782ed04cc2d
Autor:
Siu Wai, Wong, Lucy, Vivash, Ramesh, Mudududdla, Nghi, Nguyen, Stefan J, Hermans, David M, Shackleford, Judith, Field, Lian, Xue, Andrea, Aprico, Nancy C, Hancock, Mohammad, Haskali, Michael A, Stashko, Stephen V, Frye, Xiaodong, Wang, Michele D, Binder, Uwe, Ackermann, Michael W, Parker, Trevor J, Kilpatrick, Jonathan B, Baell
Publikováno v:
European journal of medicinal chemistry. 226
MER tyrosine kinase (MERTK) upregulation is associated with M2 polarization of microglia, which plays a vital role in neuroregeneration following damage induced by neuroinflammatory diseases such as multiple sclerosis (MS). Therefore, a radiotracer s
Autor:
Hermans, Stefan J., Nero, Tracy L., Morton, Craig J., Gooi, Jonathan H., Crespi, Gabriela A. N., Hancock, Nancy C., Gao, Chen, Ishii, Kenta, Markulić, Jasmina, Parker, Michael W.
Publikováno v:
Biophysical Reviews; Feb2022, Vol. 14 Issue 1, p233-255, 23p
Publikováno v:
Health & Medicine Week; 10/25/2024, p3981-3981, 1p
Autor:
Baell, Jonathan B., Leaver, David J., Hermans, Stefan J., Kelly, Gemma L., Brennan, Margs S., Downer, Natalie L., Nguyen, Nghi, Wichmann, Johannes, McRae, Helen M., Yang, Yuqing, Cleary, Ben, Lagiakos, H. Rachel, Mieruszynski, Stephen, Pacini, Guido, Vanyai, Hannah K., Bergamasco, Maria I., May, Rose E., Davey, Bethany K., Morgan, Kimberly J., Sealey, Andrew J.
Publikováno v:
Nature; Aug2018, Vol. 560 Issue 7717, p253-257, 5p, 2 Diagrams, 12 Graphs
Autor:
Hermans, Stefan J., Ascher, David B., Hancock, Nancy C., Holien, Jessica K., Michell, Belinda J., Chai, Siew Yeen, Morton, Craig J., Parker, Michael W.
Publikováno v:
Protein Science: A Publication of the Protein Society; Feb2015, Vol. 24 Issue 2, p190-199, 10p
Autor:
I. Holmes, Melanie deSilva, Ian P. Street, M.C. Chung, David J. Curtis, Stupple Paul Anthony, Julian Grusovin, Danny Ganame, Richard C. Foitzik, Alison Thistlethwaite, Romina Lessene, Gill E. Lunniss, Stephen M. Jane, Brendon J. Monahan, Elizabeth Allan, Michelle Ang Camerino, Hong Yang, Ylva E. Bozikis, Karen L. White, Rachel Lagiakos, Alexandra E. Stupple, S.J. Hermans, Marica Nikac, Scott Raymond Walker, Wilhelmus J A Kersten, Thomas S. Peat, Ben Morrow, Emma Toulmin, Hendrik Falk, Stefan Eugen Sonderegger, Michael W. Parker, Susan A. Charman, Jo-Anne Pinson, Patricia A. Pilling
Publikováno v:
Cancer Research. 75:5371-5371
Increased expression or dysregulation of protein arginine methyltransferase 5 (PRMT5) activity is associated with poor prognosis in many cancers. Through increased methylation of epigenetic and non-epigenetic targets, the aberrant activity of PRMT5 h