Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Stefan J. Frohberger"'
Autor:
Marc P. Hübner, Simon Townson, Suzanne Gokool, Senyo Tagboto, Mary J. Maclean, Guilherme G. Verocai, Adrian J. Wolstenholme, Stefan J. Frohberger, Achim Hoerauf, Sabine Specht, Ivan Scandale, Achim Harder, Martin Glenschek-Sieberth, Steffen R. Hahnel, Daniel Kulke
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 17, Iss , Pp 27-35 (2021)
Filariae are vector-borne nematodes responsible for an enormous burden of disease. Human lymphatic filariasis, caused by Wuchereria bancrofti, Brugia malayi, and Brugia timori, and onchocerciasis (caused by Onchocerca volvulus) are neglected parasiti
Externí odkaz:
https://doaj.org/article/252f3ff0161446448f30716b92ceb613
Autor:
Julia J. Reichwald, Frederic Risch, Anna-Lena Neumann, Stefan J. Frohberger, Johanna F. Scheunemann, Benjamin Lenz, Alexandra Ehrens, Wiebke Strutz, Beatrix Schumak, Achim Hoerauf, Marc P. Hübner
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Group 2 innate lymphoid cells (ILC2s) are inducers of type 2 immune responses, but their role during filarial infection remains unclear. In the present study, we used the Litomosoides sigmodontis rodent model of filariasis to analyze ILC2s during inf
Externí odkaz:
https://doaj.org/article/1acc41176560467e8afe08d122c37d69
Autor:
Johanna F. Scheunemann, Frederic Risch, Julia J. Reichwald, Benjamin Lenz, Anna-Lena Neumann, Stephan Garbe, Stefan J. Frohberger, Marianne Koschel, Jesuthas Ajendra, Maximilian Rothe, Eicke Latz, Christoph Coch, Gunther Hartmann, Beatrix Schumak, Achim Hoerauf, Marc P. Hübner
Publikováno v:
Vaccines, Vol 11, Iss 5, p 966 (2023)
More than two-hundred-million people are infected with filariae worldwide. However, there is no vaccine available that confers long-lasting protection against filarial infections. Previous studies indicated that vaccination with irradiated infective
Externí odkaz:
https://doaj.org/article/b87d9cd8fe334b3eaac4ac43de97300f
Autor:
Marc P. Hübner, Emma Gunderson, Ian Vogel, Christina A. Bulman, K.C. Lim, Marianne Koschel, Alexandra Ehrens, Stefan J. Frohberger, Martina Fendler, Nancy Tricoche, Denis Voronin, Andrew Steven, Victor Chi, Malina A. Bakowski, Ashley K. Woods, H. Michael Petrassi, Case W. McNamara, Brenda Beerntsen, Laura Chappell, William Sullivan, Mark J. Taylor, Joseph D. Turner, Achim Hoerauf, Sara Lustigman, Judy A. Sakanari
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 12, Iss , Pp 18-27 (2020)
The quinazolines CBR417 and CBR490 were previously shown to be potent anti-wolbachials that deplete Wolbachia endosymbionts of filarial nematodes and present promising pre-clinical candidates for human filarial diseases such as onchocerciasis. In the
Externí odkaz:
https://doaj.org/article/ae0698b9586a42138cd1a78a22ad6053
Autor:
Stefan J. Frohberger, Jesuthas Ajendra, Jayagopi Surendar, Wiebke Stamminger, Alexandra Ehrens, Benedikt C. Buerfent, Katrin Gentil, Achim Hoerauf, Marc P. Hübner
Publikováno v:
Parasites & Vectors, Vol 12, Iss 1, Pp 1-16 (2019)
Abstract Background Mice are susceptible to infections with the rodent filarial nematode Litomosoides sigmodontis and develop immune responses that resemble those of human filarial infections. Thus, the L. sigmodontis model is used to study filarial
Externí odkaz:
https://doaj.org/article/262c855398094f0aa02697e7a7bc880f
Autor:
Jayagopi Surendar, Indulekha Karunakaran, Stefan J. Frohberger, Marianne Koschel, Achim Hoerauf, Marc P. Hübner
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Even after successful weight reduction, obese adults tend to quickly regain the lost weight. This raises the question of whether weight loss improves the underlying chronic adipose tissue inflammation characteristic of obesity. In order to improve ou
Externí odkaz:
https://doaj.org/article/e1df77773c06416abad261c1d608e96e
Autor:
Jayagopi Surendar, Stefan J. Frohberger, Indulekha Karunakaran, Vanessa Schmitt, Wiebke Stamminger, Anna-Lena Neumann, Christoph Wilhelm, Achim Hoerauf, Marc P. Hübner
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Compared to the innate immune system, the contribution of the adaptive immune response during obesity and insulin resistance is still not completely understood. Here we demonstrate that high fat diet (HFD) increases the frequencies of activated CD4+
Externí odkaz:
https://doaj.org/article/d9c6848f1b31447e92a03aefaa7cd1f4
Autor:
Anna K. Krome, Tim Becker, Stefan Kehraus, Andrea Schiefer, Christian Steinebach, Tilman Aden, Stefan J. Frohberger, Álvaro López Mármol, Dnyaneshwar Kapote, Rolf Jansen, Lillibeth Chaverra-Muñoz, Marc P. Hübner, Kenneth Pfarr, Thomas Hesterkamp, Marc Stadler, Michael Gütschow, Gabriele M. König, Achim Hoerauf, Karl G. Wagner
Publikováno v:
Pharmaceutics, Vol 12, Iss 11, p 1105 (2020)
Novel-antibiotics are urgently needed to combat an increase in morbidity and mortality due to resistant bacteria. The preclinical candidate corallopyronin A (CorA) is a potent antibiotic against Gram-positive and some Gram-negative pathogens for whic
Externí odkaz:
https://doaj.org/article/e03acd88b74a4c9d8c536584505e42ed
Autor:
Sabine Specht, Achim Harder, Steffen Hahnel, Ivan Scandale, Marc P. Hübner, Suzanne Gokool, Senyo Tagboto, Daniel Kulke, Achim Hoerauf, Simon Townson, Guilherme G. Verocai, Mary J. Maclean, Stefan J. Frohberger, Adrian J. Wolstenholme, Martin Glenschek-Sieberth
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance
International Journal for Parasitology: Drugs and Drug Resistance, Vol 17, Iss, Pp 27-35 (2021)
International Journal for Parasitology: Drugs and Drug Resistance, Vol 17, Iss, Pp 27-35 (2021)
Filariae are vector-borne nematodes responsible for an enormous burden of disease. Human lymphatic filariasis, caused by Wuchereria bancrofti, Brugia malayi, and Brugia timori, and onchocerciasis (caused by Onchocerca volvulus) are neglected parasiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d9429a47ac78d2ccda2d88d8a977303
http://europepmc.org/articles/PMC8347670
http://europepmc.org/articles/PMC8347670
Autor:
Johanna F. Scheunemann, Frederic Risch, Julia J. Reichwald, Benjamin Lenz, Anna-Lena Neumann, Stephan Garbe, Stefan J. Frohberger, Marianne Koschel, Jesuthas Ajendra, Maximilian Rothe, Eicke Latz, Christoph Coch, Gunther Hartmann, Beatrix Schumak, Achim Hoerauf, Marc P. Hübner
Infections with helminths affect more than one billion people worldwide. Despite an urgent need there is no vaccine available that would confer long lasting protection against helminth infections. Previous studies indicated that a vaccination with ir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34a091f3e50ae8fcf36e42a8268c005f
https://doi.org/10.1101/2022.07.11.499516
https://doi.org/10.1101/2022.07.11.499516
