Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Stefan J, Hermans"'
Autor:
Luke A. Miles, Stefan J. Hermans, Gabriela A.N. Crespi, Jonathan H. Gooi, Larissa Doughty, Tracy L. Nero, Jasmina Markulić, Andreas Ebneth, Berthold Wroblowski, Daniel Oehlrich, Andrés A. Trabanco, Marie-Laure Rives, Ines Royaux, Nancy C. Hancock, Michael W. Parker
Publikováno v:
iScience, Vol 19, Iss , Pp 110-118 (2019)
Summary: Polymorphism in the microglial receptor CD33 gene has been linked to late-onset Alzheimer disease (AD), and reduced expression of the CD33 sialic acid-binding domain confers protection. Thus, CD33 inhibition might be an effective therapy aga
Externí odkaz:
https://doaj.org/article/22f8a82eaea94df5bb89f782ed04cc2d
Autor:
Siu Wai, Wong, Lucy, Vivash, Ramesh, Mudududdla, Nghi, Nguyen, Stefan J, Hermans, David M, Shackleford, Judith, Field, Lian, Xue, Andrea, Aprico, Nancy C, Hancock, Mohammad, Haskali, Michael A, Stashko, Stephen V, Frye, Xiaodong, Wang, Michele D, Binder, Uwe, Ackermann, Michael W, Parker, Trevor J, Kilpatrick, Jonathan B, Baell
Publikováno v:
European journal of medicinal chemistry. 226
MER tyrosine kinase (MERTK) upregulation is associated with M2 polarization of microglia, which plays a vital role in neuroregeneration following damage induced by neuroinflammatory diseases such as multiple sclerosis (MS). Therefore, a radiotracer s