Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Stefan Isaksson"'
Autor:
Lena Öhman, Anders Lasson, Anna Strömbeck, Stefan Isaksson, Marcus Hesselmar, Magnus Simrén, Hans Strid, Maria K. Magnusson
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Patients with ulcerative colitis (UC) have an altered gut microbiota composition, but the microbial relationship to disease activity needs to be further elucidated. Therefore, temporal dynamics of the fecal microbial community during remissi
Externí odkaz:
https://doaj.org/article/888e6863e5fa45338bf1f85f53a2768b
Autor:
Lujain Maasfeh, Anetta Härtlova, Stefan Isaksson, Johanna Sundin, Georgios Mavroudis, Otto Savolainen, Hans Strid, Lena Öhman, Maria K. Magnusson
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1415-1432 (2021)
Background & Aims: Intestinal macrophages adopt a hyporesponsive phenotype through education by local signals. Lack of proper macrophage maturation in patients with ulcerative colitis (UC) in remission may initiate gut inflammation. The aim, therefor
Externí odkaz:
https://doaj.org/article/cb556344adb14d9b9261e46d9bcea45c
Autor:
Maria K. Magnusson, Alexander Vidal, Lujain Maasfeh, Stefan Isaksson, Rajneesh Malhotra, Henric K. Olsson, Lena Öhman
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6, p 3084 (2021)
Patients with ulcerative colitis (UC) have reduced intestinal levels of short-chain fatty acids (SCFAs), including butyrate, which are important regulators of host–microbiota crosstalk. The aim was therefore to determine effects of butyrate on bloo
Externí odkaz:
https://doaj.org/article/8f83f348d88b4c33996982af7ae4736f
Publikováno v:
Cogent Medicine, Vol 5, Iss 1 (2018)
Objectives: Chromogranins (Cg) and secretogranins (Sg) are expressed by endocrine cells and may be important for the pathophysiology of ulcerative colitis (UC). We investigated dynamics of faecal granin expression in patients with UC during a period
Externí odkaz:
https://doaj.org/article/a799bb876a6947fd95f86d74ba83394c
Autor:
Otto Savolainen, Johanna Sundin, Stefan Isaksson, Hans Strid, Lena Öhman, Lujain Maasfeh, Maria K. Magnusson, Anetta Härtlova, Georgios Mavroudis
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1415-1432 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Intestinal macrophages adopt a hyporesponsive phenotype through education by local signals. Lack of proper macrophage maturation in patients with ulcerative colitis (UC) in remission may initiate gut inflammation. The aim, therefore
Autor:
Cristina Iribarren, Sofia Nordlander, Johanna Sundin, Stefan Isaksson, Otto Savolainen, Hans Törnblom, Maria K. Magnusson, Magnus Simrén, Lena Öhman
Publikováno v:
Neurogastroenterology & Motility. 34
Alteration of the host-microbiota cross talk at the intestinal barrier may participate in the pathophysiology of irritable bowel syndrome (IBS). Therefore, we aimed to determine effects of fecal luminal factors from IBS patients on the colonic epithe
Autor:
Hans Strid, Lena Öhman, Georgios Mavroudis, Stefan Isaksson, Maria K. Magnusson, Johanna Sundin, Magnus Simren
Publikováno v:
Journal of Crohn's and Colitis. 13:1450-1458
Background and Aims Alterations in the immunopathogenesis in ulcerative colitis [UC] during the disease course have been proposed. We therefore aimed to determine mucosal and systemic immune profiles in individual patients at the time of diagnosis [e
Autor:
Maria K. Magnusson, Stefan Isaksson, Magnus Simren, Lena Öhman, Hans Strid, Anders Lasson, Anna Strömbeck, Marcus Hesselmar
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Patients with ulcerative colitis (UC) have an altered gut microbiota composition, but the microbial relationship to disease activity needs to be further elucidated. Therefore, temporal dynamics of the fecal microbial community during remission and fl
Publikováno v:
Inflammatory Bowel Diseases. 23:956-966
BACKGROUND The clinical disease course of ulcerative colitis (UC) varies substantially between individuals and can currently not be reliably predicted. The gut microbiota and the host's immune defense are key players for gut homeostasis and may be li
Autor:
Stefan Isaksson, Magnus Simren, Aurore Tessier, Boris Le Nevé, Hans Törnblom, Sean M.P. Bennet, Annikka V. Polster, Lena Öhman, Sandrine Capronnier
Publikováno v:
American Journal of Gastroenterology. 111:1165-1176
Evidence suggests that patients with irritable bowel syndrome (IBS) have an altered cytokine profile, although it is unclear whether cytokines are linked with symptom severity. We aimed to determine whether global serum and mucosal cytokine profiles