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pro vyhledávání: '"Stefan Husted"'
294 Identification of MCAK Inhibitors that Induce Aneuploidy in Triple Negative Breast Cancer Models
Autor:
John Smith, Stefan Husted, Jay Pilrose, Disha Kuchangi, Stephanie C. Ems-McClung, Richard L. Carpenter, Claire E. Walczak
Publikováno v:
Journal of Clinical and Translational Science, Vol 7, Pp 88-88 (2023)
OBJECTIVES/GOALS: Microtubule poisons, like Taxol, are used to treat triple negative breast cancer (TNBC) and may induce lethal aneuploidy in cancer cells. Patients initially respond, but often develop drug resistance. New targeted drugs that cause a
Externí odkaz:
https://doaj.org/article/f7ae9f0c09394593a916ba7b9b8be76b
Autor:
Walczak, John C. Smith, Stefan Husted, Jay Pilrose, Stephanie C. Ems-McClung, Jane R. Stout, Richard L. Carpenter, Claire E.
Publikováno v:
Cancers; Volume 15; Issue 13; Pages: 3309
Standard of care for triple-negative breast cancer (TNBC) involves the use of microtubule poisons such as paclitaxel, which are proposed to work by inducing lethal levels of aneuploidy in tumor cells. While these drugs are initially effective in trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::2feeca250e033e8e9bef5455bd51af5f