Zobrazeno 1 - 10 of 139 pro vyhledávání: '"Stefan Herzig"'
1
Akademický článek
Autism-associated mutations in the CaVβ2 calcium-channel subunit increase Ba2+-currents and lead to differential modulation by the RGK-protein Gem
Autor: Patrick Despang, Sarah Salamon, Alexandra F. Breitenkamp, Elza Kuzmenkina, Stefan Herzig, Jan Matthes
Publikováno v: Neurobiology of Disease, Vol 136, Iss , Pp 104721- (2020)
Voltage-gated calcium-channels (VGCCs) are heteromers consisting of several subunits. Mutations in the genes coding for VGCC subunits have been reported to be associated with autism spectrum disorder (ASD). In a previous study, we identified electrop
Externí odkaz: https://doaj.org/article/1bcec8b5d2ae424db772baae27b7ccc5
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2
Akademický článek
Regulations and practices of structured doctoral education in the life sciences in Germany.
Autor: Daniel Lachmann, Thilo Martius, Julia Eberle, Mareike Landmann, Lena von Kotzebue, Birgit Neuhaus, Stefan Herzig
Publikováno v: PLoS ONE, Vol 15, Iss 7, p e0233415 (2020)
Structured doctoral education is increasingly preferred compared to the individual model. Several science policy organisations give recommendations on how to structure doctoral education. However, there is little research on to what extent these reco
Externí odkaz: https://doaj.org/article/64824707e7d6442abac3d38196876f4c
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3
Akademický článek
The Flex-OeCoS—a Novel Optically Accessible Test Rig for the Investigation of Advanced Combustion Processes under Engine-Like Conditions
Autor: Bruno Schneider, Christian Schürch, Konstantinos Boulouchos, Stefan Herzig, Marc Hangartner, David Humair, Silas Wüthrich, Christoph Gossweiler, Kai Herrmann
Publikováno v: Energies, Vol 13, Iss 7, p 1794 (2020)
A new test rig has been designed, built and commissioned, and is now jointly pursued to facilitate experimental investigations into advanced combustion processes (i.e., dual fuel, multi-mode) under turbulent conditions at high, engine-like temperatur
Externí odkaz: https://doaj.org/article/b4771260cc664acdbef84a12961ccdb9
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4
Akademický článek
Rare mutations of CACNB2 found in autism spectrum disease-affected families alter calcium channel function.
Autor: Alexandra F S Breitenkamp, Jan Matthes, Robert Daniel Nass, Judith Sinzig, Gerd Lehmkuhl, Peter Nürnberg, Stefan Herzig
Publikováno v: PLoS ONE, Vol 9, Iss 4, p e95579 (2014)
Autism Spectrum Disorders (ASD) are complex neurodevelopmental diseases clinically defined by dysfunction of social interaction. Dysregulation of cellular calcium homeostasis might be involved in ASD pathogenesis, and genes coding for the L-type calc
Externí odkaz: https://doaj.org/article/7a9cdf630a644d26a6e1960649af9da0
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6
Akademický článek
Time for Change - Die Implementierung des Modellstudiengangs Humanmedizin in Köln
Autor: Christoph Stosch, Klaus A. Lehmann, Stefan Herzig
Publikováno v: Zeitschrift für Hochschulentwicklung (2011)
Im Wintersemester 2003/2004 hat die Medizinische Fakultät der Universität zu Köln den Modellstudiengang Humanmedizin begonnen. Mit dem kommenden Wintersemester 2008/2009 werden die ersten Studierenden im Praktischen Jahr eingesetzt werden. Für di
Externí odkaz: https://doaj.org/article/6c7fade93f62436bbf098bc6f48236ab
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7
Akademický článek
Gαi2- and Gαi3-specific regulation of voltage-dependent L-type calcium channels in cardiomyocytes.
Autor: Sara Dizayee, Sonja Kaestner, Fabian Kuck, Peter Hein, Christoph Klein, Roland P Piekorz, Janos Meszaros, Jan Matthes, Lutz Bjrnbaumer, Bernd Nürnberg, Stefan Herzig
Publikováno v: PLoS ONE, Vol 6, Iss 9, p e24979 (2011)
BACKGROUND: Two pertussis toxin sensitive G(i) proteins, G(i2) and G(i3), are expressed in cardiomyocytes and upregulated in heart failure. It has been proposed that the highly homologous G(i) isoforms are functionally distinct. To test for isoform-s
Externí odkaz: https://doaj.org/article/9497b655bd754b1cb2a143ba17363aa8
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8
Akademický článek
Increased expression of the auxiliary beta(2)-subunit of ventricular L-type Ca(2)+ channels leads to single-channel activity characteristic of heart failure.
Autor: Roger Hullin, Jan Matthes, Sibylle von Vietinghoff, Ilona Bodi, Marta Rubio, Karen D'Souza, Ismail Friedrich Khan, Dennis Rottländer, Uta C Hoppe, Paul Mohacsi, Eva Schmitteckert, Ralf Gilsbach, Moritz Bünemann, Lutz Hein, Arnold Schwartz, Stefan Herzig
Publikováno v: PLoS ONE, Vol 2, Iss 3, p e292 (2007)
Increased activity of single ventricular L-type Ca(2+)-channels (L-VDCC) is a hallmark in human heart failure. Recent findings suggest differential modulation by several auxiliary beta-subunits as a possible explanation.By molecular and functional an
Externí odkaz: https://doaj.org/article/818264fd5b09409aa45aa7ddc4caf736
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